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Article
Duration-dependent regulation of autophagy by isoflurane exposure in aged rats
Current evidence suggests a central role for autophagy in many inflammatory brain disorders, including Alzheimer’s disease (AD). Furthermore, it is also well accepted that some i nhalation anesthetics, such as...
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Article
Open AccessA Volumetric and Functional Connectivity MRI Study of Brain Arginine-Vasopressin Pathways in Autistic Children
Dysfunction of brain-derived arginine-vasopressin (AVP) systems may be involved in the etiology of autism spectrum disorder (ASD). Certain regions such as the hypothalamus, amygdala, and hippocampus are known ...
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Article
Open AccessRegulatory Effect of General Anesthetics on Activity of Potassium Channels
General anesthesia is an unconscious state induced by anesthetics for surgery. The molecular targets and cellular mechanisms of general anesthetics in the mammalian nervous system have been investigated during...
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Article
Association of Polygenic Risk Score with Age at Onset and Cerebrospinal Fluid Biomarkers of Alzheimer’s Disease in a Chinese Cohort
To evaluate whether the polygenic profile modifies the development of sporadic Alzheimer’s disease (sAD) and pathological biomarkers in cerebrospinal fluid (CSF), 462 sAD patients and 463 age-matched cognitive...