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Article
Open AccessGenome-wide analysis of chicken snoRNAs provides unique implications for the evolution of vertebrate snoRNAs
Small nucleolar RNAs (snoRNAs) represent one of the largest groups of functionally diverse trans-acting non-protein-coding (npc) RNAs currently known in eukaryotic cells. Chicken snoRNAs have been very poorly ...
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Article
Open AccessSnoRNAs from the filamentous fungus Neurospora crassa: structural, functional and evolutionary insights
SnoRNAs represent an excellent model for studying the structural and functional evolution of small non-coding RNAs involved in the post-transcriptional modification machinery for rRNAs and snRNAs in eukaryotic...
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Article
Addition of HPMA affects seed germination, plant growth and properties of heavy saline-alkali soil in northeastern China: comparison with other agents and determination of the mechanism
China has a large area of inland saline-alkali land, equivalent to 40% of the total cultivated land in the country. The principal features of these lands are high salt content, high pH, and poor soil structure...
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Article
Isolation and Phylogenetic Analysis of H1N1 Swine Influenza Virus from Sick Pigs in Southern China
Two swine influenza (SI) H1N1 virus was isolated from a pig during a severe outbreak of respiratory disease in south China. The two H1N1 influenza viruses were classical SI virus. A/swine/Guangdong/L6/09 is cl...
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Article
Analysis of the elemental sulfur bio-oxidation by Acidithiobacillus ferrooxidans with sulfur K-edge XANES
Elemental sulfur bio-oxidation by the typical acidophilic sulfur-oxidizing microbe Acidithiobacillus ferrooxidans was investigated by using the technique of sulfur K-edge XANES spectroscopy. Our results showed th...
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Article
RNA-seq analysis of prostate cancer in the Chinese population identifies recurrent gene fusions, cancer-associated long noncoding RNAs and aberrant alternative splicings
There are remarkable disparities among patients of different races with prostate cancer; however, the mechanism underlying this difference remains unclear. Here, we present a comprehensive landscape of the tra...
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Article
Association of angiotensin-converting enzyme gene 2350 G/A polymorphism with diabetic retinopathy in Chinese Han population
The angiotensin-converting enzyme (ACE) gene is one of the most studied candidate genes related to diabetic retinopathy (DR). ACE 2350 G/A polymorphism (rs4343) is known among the polymorphisms of this gene to...
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Article
RNA-seq analysis of prostate cancer in the Chinese population identifies recurrent gene fusions, cancer-associated long noncoding RNAs and aberrant alternative splicings
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Article
Open AccessObligate mutualism within a host drives the extreme specialization of a fig wasp genome
Fig pollinating wasps form obligate symbioses with their fig hosts. This mutualism arose approximately 75 million years ago. Unlike many other intimate symbioses, which involve vertical transmission of symbion...
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Article
Open AccessNew function for Escherichia coli xanthosine phophorylase (xapA): genetic and biochemical evidences on its participation in NAD+ salvage from nicotinamide
In an effort to reconstitute the NAD+ synthetic pathway in Escherichia coli (E. coli), we produced a set of gene knockout mutants with deficiencies in previously well-defined NAD+ de novo and salvage pathways. Un...
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Article
Anthocyanin biosynthesis is differentially regulated by light in the skin and flesh of white-fleshed and teinturier grape berries
Light exclusion reduces the concentration and modifies the composition of grape anthocyanins, by altering the expression of genes involved in anthocyanin biosynthesis and transport, in a cultiv...
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Article
Open AccessComplete genome sequence and genomic characterization of Microcystis panniformis FACHB 1757 by third-generation sequencing
The cyanobacterial genus Microcystis is well known as the main group that forms harmful blooms in water. A strain of Microcystis, M. panniformis FACHB1757, was isolated from Meiliang Bay of Lake Taihu in August 2...
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Article
Open AccessDrought-responsive WRKY transcription factor genes TaWRKY1 and TaWRKY33 from wheat confer drought and/or heat resistance in Arabidopsis
Drought stress is one of the major causes of crop loss. WRKY transcription factors, as one of the largest transcription factor families, play important roles in regulation of many plant processes, including dr...
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Article
The complete chloroplast genome of a vulnerable species Champereia manillana (Opiliaceae)
Champereia manillana (Bl.) Merr. is a vulnerable plant from the family Opiliaceae. The complete chloroplast genome (plastome) of Opiliaceae family was sequenced for the first time. The pl...
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Article
The extracellular domain of Staphylococcus aureus LtaS binds insulin and induces insulin resistance during infection
Insulin resistance is a risk factor for obesity and diabetes and predisposes individuals to Staphylococcus aureus colonization; however, the contribution of S. aureus to insulin resistance remains unclear. Here, ...
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Article
Integrated genomic and transcriptomic insights into the two-component high-affinity nitrate transporters in allotetraploid rapeseed
The two-component high-affinity nitrate (NO3-) transport system (THATS) proteins (NRT2/NAR2) play key roles in the efficient nitrogen (N) uptake and transport under N limitations. We aimed at uncovering the core ...
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Article
Overexpression of gene encoding the key enzyme involved in proline-biosynthesis (PuP5CS) to improve salt tolerance in switchgrass (Panicum virgatum L.)
Genetic improvement through overexpressing PuP5CS in switchgrass is feasible for enhancing plant salt stress tolerance.
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Article
Inheritance patterns of anthocyanins in berry skin and flesh of the interspecific population derived from teinturier grape
Successful cross-breeding requires the investigation into the inheritance pattern of desirable traits. The present study recorded the segregation in coloration and analyzed anthocyanin concentration and compos...
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Article
Bioinformatic prediction of critical genes and pathways involved in longevity in Drosophila melanogaster
The pursuit of longevity has been the goal of humanity since ancient times. Genetic alterations have been demonstrated to affect lifespan. As increasing numbers of pro-longevity genes and anti-longevity genes ...
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Article
Open AccessThe hornwort genome and early land plant evolution
Hornworts, liverworts and mosses are three early diverging clades of land plants, and together comprise the bryophytes. Here, we report the draft genome sequence of the hornwort Anthoceros angustus. Phylogenomic ...