1,505 Result(s)
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Medicine/Public Health, general
** Chung
Article
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Article
The Enzymes of Lecithin Biosynthesis in Human Newborn Lungs. III. Phosphorylcholine Glyceride Transferase
Extract: Phosphorylcholine glyceride transferase (EC. 2.7.8.2), the enzyme responsible for the final step of lecithin biosynthesis via the cytidine diphosphorylcholine (CDP-choline) pathway, is active in human ne...
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AGE-DEPENDENT ELIMINATION OF HEXACHLOROPHENE (HCP) IN NEONATAL RODENTS: POSSIBLE ROLE OF ENTEROHEPATIC RECIRCULATION
We have described previously an increased sensitivity of immature rodents to HCP, a finding which may relate to the reported high incidence of suggestive neuropathological changes found in exposed low-birth-we...
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RENAL PHOSPHATE CLEARANCE IN FETAL LAMBS
The renal clearance of phosphate (P) was studied in 4 groups of fetal lambs. In group I, acute extracellular fluid (ECF) expansion was done in 4 fetuses by infusing Ringer's lactate without Ca++. In group II, ECF...
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593 POST-THYMIC T CELL LYMPHOMA: OCCURRENCE IN THREE SIBLINGS AND ASSOCIATION WITH GARDNER'S SYNDROME
Three siblings developed a similar type of lymphoblastic lymphoma. Like their father, they all had multiple cafe au lait spots, and one was found at autopsy to have intestinal polyps typical of Gardner's syndr...
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91 CROSS-SECTIONAL ECHOCARDIOGRAPHY OF ATRIAL SEPTUM IN D-TRANSPOSITION OF GREAT VESSELS
Seven infants with d-Transposition of Great Vessels(d-TGV) were evaluated by cross-sectional echocardiography(C Echo). The ages ranged 2 days to 7 months. Five patients(pts) were examined pre-and post-atrial s...
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Renal Phosphate Clearance in Fetal Lambs
Summary: The purpose of this study was to investigate the possible role of diminished phosphate clearance by the fetal kidney in production of relative fetal hyperphosphatemia. Stimuli known to affect renal ph...
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Congenital Abnormalities Induced by Heterologous Antisera Directed Against Rat Kidney Glycoproteins Isolated by Concanavalin A Affinity Chromatography
Summary: It has been well established that heterologous antisera against whole rat kidney homogenate when injected into pregnant rats during the embryonic organogenetic period may induce abnormal embryonic dev...
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390 HORMONAL-METAL ION INTERACTION IN TESTICULAR FEMINIZATION
Testicular feminization syndrome, an X-linked recessive disorder in humans, is caused by the insensitivity of target organs such as testes to the stimulation of androgens. Two animal models are available, the ...
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1432 TREATMENT OF NEONATAL CHRONIC LUNG DISEASE WITH FUROSEMIDE
Long term furosemide therapy has been recommended for neonatal chronic lung disease. 28 preterm infants (986±60 gm) with stable or worsening chronic lung disease due to bronchopulmonary dysplasia or chronic pu...
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FEVER IN INFANTS AND YOUNG CHILDREN WITH SICKLE CELL DISEASE (SCD)
Forty-four patients with SCD (39 SS and 5 SC disease), aged ≤ 5 yrs (mean 28 ± 17 mths) were hospitalized for 140 febrile episodes (temperature ≥ 38.4°C.) from Jan. 1978 to July 1983. All received continuous o...
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CLONING OF cDNA ENCODING BOVINE 21-HYDROXYLASE
Over 90% of cases of congenital adrenal hyperplasia are due to disordered 21-hydroxylation, which converts progesterone and 17-hydroxyprogestone (17-OHP) to DOC and 11-deoxycortisol. 21-hydroxylase is a single...
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PLASMA ANTITHROMBIN III LEVELS IN CHILDREN WITH HOMOZYGOUS SICKLE CELL DISEASE (SCD)
Plasma Antithrombin III activity (AT-IIIAc) and antigen (AT-IIIAgn) levels were determined in 75 children with SCD in the steady state aged 2 to 19 yrs (mean of 9.6 ± 5.6) and in matched controls. Thirty-three...
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CHRONIC RESERPINATION OF SUCKLING RATS DOES NOT INTERFERE WITH THE DEVELOPMENTAL ACCUMULATION OF PANCREATIC ENZYMES
We tested whether chronic reserpine treatment disturbed the exocrine pancreatic development of suckling rats. Rat pups (4 days old) were given reserpine (R) (50 μg/kg i.p.) or vehicle (C) daily until sacrifice...
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EFFECT OF PARENTERAL NUTRITION(TPN) ON POSTNATAL DEVELOPMENT OF THE SMALL INTESTINE
Although TPN is used frequently in young infants, little information is available regarding its effect on postnatal development of the gut. The effect of TPN on ontogeny of the small intestine was examined in ...
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EFFECTS OF SERUM FROM PATIENTS WITH KAWASAKI DISEASE ON CULTURED ARTERIAL ENDOTHELIAL AND SMOOTH MUSCLE CELLS
The possible presence of a toxic substance in the serum of patients with Kawasaki disease (KD) causing the pathogenesis of the disease was investigated by examining the effects of acute phase serum (Kawasaki s...
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Effect of Chronic Reserpine Treatment on the Pancreases of Neonatal Rats
ABSTRACT: Chronic reserpine treatment of adult rats results in the accumulation of pancreatic enzymes and reduction of their discharge. These changes are reminiscent of those in cystic fibrosis. Since the majo...
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437 MOLECULAR CLONING OF THE BOVINE 21 HYDROXYLASE GENE
About 1 in 5000 people has congenital adrenal hyperplasia due to disordered 21 hydroxylation. 21 hydroxylase is a single specific 49000 daltori microsomal cytochrome P450, (P450c21) which is less than 0.1% of ...
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839 USE OF OLIGONUCLEOTIDES WITH NON-HUMAN SEQUENCES FOR PROBING HUMAN DNA
Short, chemically synthesized mixed-sequence oligonucleotides have been used to identify cDNA and gene clones. Recently, pairs of 19 to 23 base unique-sequence oligos differing at a single base have been used ...
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234 ABERRANT ZINC BINDING IN TESTES OF TESTICULAR FEMINIZATION RATS
Testicular feminization (Tfm) is an inherited form of male pseudohermaphroditism. In the rat, this syndrome is manifested by an absence of androgen dependent differentiation, small cryptorchid testes and infer...
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1386 PLASMA PROSTAGLANDIN RESPONSE TO INDOMETHACIN THERAPY FOR PATENT DUCTUS ARTERIOSUS IN PREMATURE INFANTS
To elucidate the relationship between ductal patency (PDA), plasma prostaglandins (PG) and indanethacin (IN), 55 infants <1750 gms at birth were monitored prospectively for a hemodynamically significant PDA by...
