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Article
Open AccessUniversal Murray’s law for optimised fluid transport in synthetic structures
Materials following Murray’s law are of significant interest due to their unique porous structure and optimal mass transfer ability. However, it is challenging to construct such biomimetic hierarchical channel...
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Article
Open AccessBenchmarking highly entangled states on a 60-atom analogue quantum simulator
Quantum systems have entered a competitive regime in which classical computers must make approximations to represent highly entangled quantum states1,2. However, in this beyond-classically-exact regime, fidelity ...
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Open AccessThe immune regulation and therapeutic potential of the SMAD gene family in breast cancer
Breast cancer is a serious threat to human health. The transforming growth factor-β signaling pathway is an important pathway involved in the occurrence and development of cancer. The SMAD family genes are res...
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Article
Changes of B cell subsets in different types of diabetes and its effect on the progression of latent autoimmune diabetes in adults
Developmental abnormalities in B cells is one of the key players in autoimmune diabetes, but little is known about its role in latent autoimmune diabetes in adults (LADA). This study aimed to investigate the d...
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Open AccessSmart touchless human–machine interaction based on crystalline porous cages
The rise of touchless technology, driven by the recent pandemic, has transformed human-machine interaction (HMI). Projections indicate a substantial growth in the touchless technology market, nearly tripling f...
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Article
Open AccessA surface strategy boosting the ethylene selectivity for CO2 reduction and in situ mechanistic insights
Electrochemical reduction of carbon dioxide into ethylene, as opposed to traditional industrial methods, represents a more environmentally friendly and promising technical approach. However, achieving high act...
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Article
Open AccessToripalimab plus capecitabine in the treatment of patients with residual nasopharyngeal carcinoma: a single-arm phase 2 trial
Patients with residual nasopharyngeal carcinoma after receiving definitive treatment have poor prognoses. Although immune checkpoint therapies have achieved breakthroughs for treating recurrent and metastatic ...
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Article
Open AccessLarge mechanical properties enhancement in ceramics through vacancy-mediated unit cell disturbance
Tailoring vacancies is a feasible way to improve the mechanical properties of ceramics. However, high concentrations of vacancies usually compromise the strength (or hardness). We show that a high elasticity a...
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Open AccessA retrospective study of postoperative targeted therapy in ALK-positive lung cancer
In this study, we aim to investigate the therapeutic effect and safety of ALK inhibitor in ALK-positive lung cancer patients. 59 patients with ALK-positive lung cancer from August 2013 to August 2022 were retr...
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Open AccessA semiconductor-electrocatalyst nano interface constructed for successive photoelectrochemical water oxidation
Photoelectrochemical water splitting has long been considered an ideal approach to producing green hydrogen by utilizing solar energy. However, the limited photocurrents and large overpotentials of the anodes ...
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Article
Open AccessThe relationship between physical activity and premenstrual syndrome in senior high school students: a prospective study
Reproductive-aged women experience somatic and affective symptoms of premenstrual syndrome (PMS) which affect their daily life and work, but there are limited tracking data on senior high school-age female stu...
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Open AccessUsing machine learning to estimate the incidence rate of intimate partner violence
It is difficult to accurately estimate the incidence rate of intimate partner violence (IPV) using traditional social survey methods because IPV victims are often reluctant to disclose their experiences, leadi...
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Open AccessAuthor Correction: Risk factors and geographic disparities in premature cardiovascular mortality in US counties: a machine learning approach
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Open AccessScalable and switchable CO2-responsive membranes with high wettability for separation of various oil/water systems
Smart membranes with responsive wettability show promise for controllably separating oil/water mixtures, including immiscible oil-water mixtures and surfactant-stabilized oil/water emulsions. However, the memb...
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Open AccessRisk factors and geographic disparities in premature cardiovascular mortality in US counties: a machine learning approach
Disparities in premature cardiovascular mortality (PCVM) have been associated with socioeconomic, behavioral, and environmental risk factors. Understanding the “phenotypes”, or combinations of characteristics ...
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Article
Open AccessDe novo analysis of bulk RNA-seq data at spatially resolved single-cell resolution
Uncovering the tissue molecular architecture at single-cell resolution could help better understand organisms’ biological and pathological processes. However, bulk RNA-seq can only measure gene expression in c...
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Article
Open AccessAnalysis of immune related gene expression profiles and immune cell components in patients with Barrett esophagus
Barrett's esophagus (BE) is a well-known precancerous condition of esophageal adenocarcinoma. However, the immune cells and immune related genes involved in BE development and progression are not fully underst...
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Open AccessA Chinese tale of three regions: a century of China in thousands of films
Over the past 70 years, because of their different historical and social contexts, the film industries of China’s three regions, namely mainland China, Taiwan, and the Hong Kong Special Administrative Region (...
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Article
Open AccessTransition-metal-free allylation of 2-azaallyls with allyl ethers through polar and radical mechanisms
Allylation of nucleophiles with highly reactive electrophiles like allyl halides can be conducted without metal catalysts. Less reactive electrophiles, such as allyl esters and carbonates, usually require a tr...
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Open AccessEnvironmental influences on sinking rates and distributions of transparent exopolymer particles after a typhoon surge at the Western Pacific
A multidisciplinary approach was used to investigate the causes of the distributions and sinking rates of transparent exopolymer particles (TEPs) during the period of September–October (2017) in the Western Pa...