163 Result(s)
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Article
Role of Exercise on Inflammation Cytokines of Neuropathic Pain in Animal Models
Neuropathic pain (NP) resulting from a lesion or disease of the somatosensory system can lead to loss of function and reduced life quality. Neuroinflammation plays a vital role in the development and maintenan...
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Article
Ultrasound-driven self-decomposition porphyrins as metal-free CO precursors for gas and sonodynamic synergistic therapy
Carbon monoxide (CO) is an endogenous therapeutic gas with an anti-tumor effect. The precise delivery and controlled release of CO in tumor tissues play crucial roles in anti-cancer treatment. However, efficient
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Article
Open AccessSRY-Box transcription factor 9 triggers YAP nuclear entry via direct interaction in tumors
The translocation of YAP from the cytoplasm to the nucleus is critical for its activation and plays a key role in tumor progression. However, the precise molecular mechanisms governing the nuclear import of YA...
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Article
Open AccessEpiberberine: a potential rumen microbial urease inhibitor to reduce ammonia release screened by targeting UreG
Rumen microbial urease inhibitors have been proposed for regulating nitrogen emission and improving nitrogen utilization efficiency in ruminant livestock industry. However, studies on plant-derived natural inh...
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Article
Open AccessEvidence for chronic headaches induced by pathological changes of myodural bridge complex
Clinical studies have shown that there may be a certain relationship between pathological changes of the myodural bridge complex (MDBC) and chronic headaches of unknown cause. But there is still a lack of expe...
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Article
Efficient LiDAR/inertial-based localization with prior map for autonomous robots
A rapid and accurate localization scheme is significant for the application of autonomous robots in a prior map. However, this task remains challenging in the real-time requirement due to the complex scan matc...
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Article
Ultra-precision milling and grinding for large-sagittal MgF2 aspheric optical elements
Ultra-precision machining for large-sagittal aspheric optical elements has become one of the research hotspots in the world’s processing and manufacturing field in recent years. This paper mainly studies the p...
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Article
Open AccessmiR-541 is associated with the prognosis of liver cirrhosis and directly targets JAG2 to inhibit the activation of hepatic stellate cells
The activation of hepatic stellate cells (HSCs) has been emphasized as a leading event of the pathogenesis of liver cirrhosis, while the exact mechanism of its activation is largely unknown. Furthermore, the n...
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Article
Acid corrosion micro-macro mechanism of enzyme-induced carbonate precipitation (EICP) treated sandy soils
Carbon dioxide (CO2) geological sequestration is an effective way to control CO2 emissions, and the geological safety in CO2 injection project is the most concern problem. Enzyme-induced carbonate precipitation (...
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Article
Open AccessMagnetic resonance imaging-based classification of the myodural bridge complex and its influencing factors
Cerebrospinal fluid (CSF) circulation is considered the third circulation of the human body. Recently, some scholars have proposed the myodural bridge (MDB) as a novel power source for CSF flow. Moreover, the ...
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Article
Dietary L-carnitine supplementation changes lipid metabolism and glucose utilization of Rhynchocypris lagowskii fed diets with different lipid sources
The widely available crop oil is an effective alternative to the increasingly scarce marine fish oil. However, simple alternative strategies have led to declining growth and the edible value of farmed fish. It...
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Chapter and Conference Paper
Design of MOOC Response System Based on Intelligent Algorithms
With the rapid development of the internet era and online education, large-scale open online course MOOC has successfully achieved a high-end knowledge interconnection and exchange mode. By adopting diversifie...
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Article
Open AccessTranscriptome-wide map of N6-methyladenosine (m6A) profiling in coronary artery disease (CAD) with clopidogrel resistance
Clopidogrel resistance profoundly increases the risk of major cardiovascular events in coronary artery disease (CAD) patients. Here, we comprehensively analyse global m6A modification alterations in clopidogre...
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Article
Open AccessADP-dependent glucokinase controls metabolic fitness in prostate cancer progression
Cell metabolism plays a pivotal role in tumor progression, and targeting cancer metabolism might effectively kill cancer cells. We aimed to investigate the role of hexokinases in prostate cancer (PCa) and iden...
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Article
Open AccessHighly efficient flexible structured metasurface by roll-to-roll printing for diurnal radiative cooling
An ideal radiative cooler requires accurate spectral control capability to achieve efficient thermal emission in the atmospheric transparency window (8–13 μm), low solar absorption, good stability, scalability...
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Article
Open AccessConstruction of a prediction model for rebleeding in patients with acute upper gastrointestinal bleeding
The incidence of rebleeding in patients with upper gastrointestinal bleeding (UGIB) remains despite advances in intervention approaches. Therefore, early prediction of the risk of rebleeding could help to grea...
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Article
Medial stability and lateral flexibility of the collateral ligaments during mid-range flexion in medial-pivot total knee arthroplasty patients demonstrates favorable postoperative outcomes
The objectives of the present study were to investigate the length change in different bundles of the superficial medial collateral ligament (sMCL) and lateral collateral ligament (LCL) during lunge, and to ev...
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Article
Open AccessCorrelations between moral courage, moral sensitivity, and ethical decision-making by nurse interns: a cross-sectional study
Clinical decision-making involves ethical issues that become more and more complex. Nurse interns must be more skilled in making rational and timely decisions when facing ethical dilemmas. The contributing fac...
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Article
Open AccessGlomerular deposition of fibrinogen predicts good prognosis of IgA nephropathy: a single-center cohort study
It has been proven that fibrinogen deposition exists in IgA nephropathy (IgAN), but its clinical significance has not been identified. We aim to investigate the clinical implication of fibrinogen deposition in...
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Article
Pathological Response and Tumor Immune Microenvironment Remodeling Upon Neoadjuvant ALK-TKI Treatment in ALK-Rearranged Non-Small Cell Lung Cancer
Anaplastic lymphoma kinase-tyrosine kinase inhibitors (ALK-TKI; ALKi) have shown potent antitumor activity in metastatic non-small-cell lung cancer (NSCLC) with ALK rearrangement (ALK+); however, their efficac...
