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The use of intraluminal PRESERFLO stenting in avoiding early postoperative hypotony
PurposePostoperative hypotony following PRESERFLO MicroShunt (PMS) implantation is a frequent cause of complications such as choroidal detachment and...
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SP1 promotes high glucose-induced lens epithelial cell viability, migration and epithelial-mesenchymal transition via regulating FGF7 and PI3K/AKT pathway
BackgroundDiabetic cataract (DC) is a common complication of diabetes and its etiology and progression are multi-factorial. In this study, the roles...
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OCTA: Essential or Gimmick?
This commentary article delves into the transformative role of optical coherence tomography angiography (OCTA) in diagnosing and managing a wide...
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The effect of four loading intravitreal aflibercept injections on macular fluid in treatment-naïve neovascular age-related macular degeneration
PurposeTo evaluate the effect of four versus three loading aflibercept injections on macular fluid resolution and visual acuity (VA) in exudative...
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A streamlined method to generate endothelial cells from human pluripotent stem cells via transient doxycycline-inducible ETV2 activation
The development of reliable methods for producing functional endothelial cells (ECs) is crucial for progress in vascular biology and regenerative...
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Assessment of objective visual function following idebenone administration in patients with leber hereditary optic neuropathy
PurposeTo objectively assess visual function in Leber’s Hereditary Optic Neuropathy (LHON) patients; this study evaluated pre- and post-idebenone...
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Comparison of the repeatability and reproducibility of corneal thickness map** using optical coherence tomography according to tear film break-up time
BackgroundTo compare the repeatability and reproducibility of corneal and corneal epithelial thickness map** using anterior segment optical...
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Povidone-iodine in vitro antiseptic efficacy as a function of exposure duration, concentration, preparation, and length of storage
PurposeAlthough 5% povidone-iodine (PVP-I) is frequently used as an ocular antiseptic agent, there is a lack of consensus regarding the effects of...
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Choroidal and retinal vascular changes in HLA-B27-associated anterior uveitis
PurposeTo quantitatively analyze choroidal and retinal vascular changes in HLA-B27-associated anterior uveitis.
Study DesignA retrospective study.
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Approaches to Restoring Lacrimal Gland Function: From stem Cells to Tissue Engineering
Purpose of ReviewWe review the latest developments in restoration of lacrimal gland function in dry eye disease and promising methods to generate...
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IOL calculation using six formulas in children undergoing lens extraction and primary IOL implantation with and without posterior optic capture
PurposeTo evaluate formulas for intraocular lens (IOL) calculation in children undergoing lens extraction and IOL implantation.
Methods ... -
Somatic RIT1 delins in arteriovenous malformations hyperactivate RAS-MAPK signaling amenable to MEK inhibition
Arteriovenous malformations (AVM) are benign vascular anomalies prone to pain, bleeding, and progressive growth. AVM are mainly caused by mosaic...
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Advances in the diagnosis and treatment of acute acquired comitant esotropia
Acute acquired comitant esotropia (AACE) is mainly characterized by sudden onset, accompanied by diplopia, without extraocular muscles paralysis or...
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Long-term effectiveness and safety of XEN45 in open-angle glaucoma patients
BackgroundTo investigate the long-term effectiveness and safety of XEN45 implant, either alone or in combination with phacoemulsification, in eyes...
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Vitamin D alleviation of oxidative stress in human retinal pigment epithelial cells
BackgroundOxidative stress-induced retinal pigment epithelium (RPE) cell damage is a major factor in age-related macular degeneration (AMD). Vitamin D
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Factors affecting prognosis and need for anti-vascular endothelial growth factor injections in wet age-related macular degeneration
PurposeTo understand factors affecting visual prognosis and the number of intravitreal antivascular endothelial growth factor (anti-VEGF) injections...
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Site-specific genetic and functional signatures of aortic endothelial cells at aneurysm predilection sites in healthy and AngII ApoE−/− mice
Aortic aneurysm is characterized by a pathological dilation at specific predilection sites of the vessel and potentially results in life-threatening...