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The interplay of inflammation and remyelination: rethinking MS treatment with a focus on oligodendrocyte progenitor cells
BackgroundMultiple sclerosis (MS) therapeutic goals have traditionally been dichotomized into two distinct avenues: immune-modulatory-centric...
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Estrogen receptor beta signaling enhances extinction memory recall for heroin-conditioned cues in a sex- and region-specific manner
Return to use, or relapse, is a major challenge in the treatment of opioid use disorder (OUD). Relapse can be precipitated by several factors,...
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Early biomarkers in the presymptomatic phase of cognitive impairment: changes in the endocannabinoidome and serotonergic pathways in Alzheimer's-prone mice after mTBI
BackgroundDespite extensive studies on the neurobiological correlates of traumatic brain injury (TBI), little is known about its molecular...
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Automated classification of brain MRI reports using fine-tuned large language models
PurposeThis study aimed to investigate the efficacy of fine-tuned large language models (LLM) in classifying brain MRI reports into pretreatment,...
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Sensory processing patterns among children with autism spectrum disorder (ASD) and attention deficit hyperactivity disorder (ADHD) using short sensory profile and evoked potentials: a case–control study
BackgroundBoth autism spectrum disorder (ASD) and attention-deficit hyperactivity disorder (ADHD) are early neurodevelopmental disorders that present...
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Does using artificial intelligence assistance accelerate skill decay and hinder skill development without performers’ awareness?
Artificial intelligence in the workplace is becoming increasingly common. These tools are sometimes used to aid users in performing their task, for...
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The Evolution of Symbolic Thought: At the Intersection of Schizophrenia Psychopathology, Ethnoarchaeology, and Neuroscience
The human capacity for symbolic representation arises, evolutionarily and developmentally, from the exploitation of a widespread sensorimotor...
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Trauma, adversity, and biological aging: behavioral mechanisms relevant to treatment and theory
Although stress and adversity are largely universal experiences, people exposed to greater hardship are at increased risk for negative health...
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Associations between the choroid plexus and tau in Alzheimer’s disease using an active learning segmentation pipeline
BackgroundThe cerebrospinal fluid (CSF), primarily generated by the choroid plexus (ChP), is the major carrier of the glymphatic system. The...
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Unleashing the Neurotherapeutic Potential: The Crucial Role of miR-206-3p in Facilitating Hsp90aa1-Mediated Central Nervous System Injuries During Heat Stroke
This study aims to explore the molecular mechanisms of miR-206-3p in regulating Hsp90aa1 and its involvement in the central nervous system (CNS)...
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The Association Between the Impact of COVID-19 and Internalizing Problems Among Children and Adolescents with ADHD: The Moderating Role of Parental Anxiety
Previous research has identified an increase in internalizing problems during the COVID-19 pandemic in children and adolescents with...
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Development and validation of a novel screening tool for deep vein thrombosis in patients with spinal cord injury: A five-year cross-sectional study
Study designCross-sectional study.
ObjectivesDeep vein thrombosis (DVT) presents a significant risk of complication in patients with spinal cord...
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Disruption of neural periodicity predicts clinical response after deep brain stimulation for obsessive-compulsive disorder
Recent advances in surgical neuromodulation have enabled chronic and continuous intracranial monitoring during everyday life. We used this...
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High resolution imaging of human development: shedding light on contrast agents
BackgroundVisualizing (micro)vascular structures remains challenging for researchers and clinicians due to limitations in traditional radiological...
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Promoting Adolescent Safer Gambling Through Self-Referent Counterfactual Thinking and Knowledge of Probabilistic Outcome
Research have continued to advocate for various safer gambling strategies (SGs) to curb initiation and sustenance of problem gambling through the...
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The positive reinforcing effects of cocaine and opposite-sex social contact: roles of biological sex and estrus
RationalePreclinical studies report that drug use and social contact mutually influence the reinforcing effects of one another. Most of these studies...
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Dual-task improvement of older adults after treadmill walking combined with blood flow restriction of low occlusion pressure: the effect on the heart–brain axis
ObjectiveThis study explored the impact of one session of low-pressure leg blood flow restriction (BFR) during treadmill walking on dual-task...
