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Nesting biology of Tetrapedia amplitarsis (Hymenoptera: Apidae: Tetrapediini)
Tetrapedia amplitarsis is an oil-collecting solitary bee that nests in pre-existing cavities and differs from the other species of the genus in...
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Replicase gene mediated RNA silencing mechanism confers resistance against groundnut bud necrosis virus in tomato (Lycopersicon esculentum Mill.)
Groundnut bud necrosis virus (GBNV), a member of the genus Orthotospovirus , is the most devastating pathogen causing bud blight of tomato and causes...
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Green synthesis of Agaricus avensis-mediated silver nanoparticles for improved catalytic efficiency of tyrosine hydroxylase towards potential biomedical implications
The present study deals with the bio-fabrication of AgA-AgNPs utilizing edible mushroom Agaricus arvensis as a reductant for improved stability and...
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YTH domain family protein 3 accelerates non-small cell lung cancer immune evasion through targeting CD8+ T lymphocytes
Immune evasion is one of the critical hallmarks of malignant tumors, especially non-small cell lung cancer (NSCLC). Emerging findings have...
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Lactate modulates zygotic genome activation through H3K18 lactylation rather than H3K27 acetylation
In spite of its essential role in culture media, the precise influence of lactate on early mouse embryonic development remains elusive. Previous...
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Expression genome-wide association study identifies key regulatory variants enriched with metabolic and immune functions in four porcine tissues
BackgroundIntegration of high throughput DNA genoty** and RNA-sequencing data enables the discovery of genomic regions that regulate gene...
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Taxonomic diversity and environmental tolerance of cultivable extremophilic bacteria from a high-altitude meltwater pond on Ojos del Salado (Chile)
Earth harbors unique environments where only microorganisms adapted to extreme conditions, known as extremophiles, can survive. This study focused on...
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Nuclear actin assembly is an integral part of decidualization in human endometrial stromal cells
Decidualization of the human endometrium is critical for establishing pregnancy and is entailed by differentiation of endometrial stromal cells...
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Exploring uncharted waters: insights into groundwater zooplankton of the Brazilian semiarid region
The subterranean environments of the Caatinga drylands (Brazilian biome) host a diverse array of aquatic systems and diversity, comprising both...
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CD74 is a functional MIF receptor on activated CD4+ T cells
Next to its classical role in MHC II-mediated antigen presentation, CD74 was identified as a high-affinity receptor for macrophage migration...
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OBSERVE: guidelines for the refinement of rodent cancer models
Existing guidelines on the preparation (Planning Research and Experimental Procedures on Animals: Recommendations for Excellence (PREPARE)) and...
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Dexmedetomidine and argon in combination against ferroptosis through tackling TXNIP-mediated oxidative stress in DCD porcine livers
Graft availability from donation after circulatory death (DCD) is significantly limited by ischaemia reperfusion (IR) injury. Effective strategies to...
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An end-to-end workflow to study newly synthesized mRNA following rapid protein depletion in Saccharomyces cerevisiae
BackgroundGene transcription by RNA polymerase II is a fundamental process in eukaryotic cells. The precise regulation of transcription is necessary...
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Prevalence and antimicrobial susceptibility patterns of bacteria colonizing the external ocular surfaces of patients undergoing ocular surgeries at Bugando Medical Center in Mwanza, Tanzania
ObjectiveUnderstanding microbiota colonizing ocular surfaces is key to expedite antibiotic prophylactic options for ocular surgeries, and therefore,...
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A RsrC-RsrA-RsrB transcriptional circuit positively regulates polysaccharide-degrading enzyme biosynthesis and development in Penicillium oxalicum
Filamentous fungi produce polysaccharide-degrading enzymes, which is controlled by poorly understood transcriptional circuits. Here we show that a...
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Activation of AMPD2 drives metabolic dysregulation and liver disease in mice with hereditary fructose intolerance
Hereditary fructose intolerance (HFI) is a painful and potentially lethal genetic disease caused by a mutation in aldolase B resulting in...
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Plant roots affect free-living diazotroph communities in temperate grassland soils despite decades of fertilization
Fixation of atmospheric N 2 by free-living diazotrophs accounts for an important proportion of nitrogen naturally introduced to temperate grasslands....
