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Retrospective analysis of reference intervals for dried blood spot based ms/ms newborn screening programs in Chinese preterm neonates: a nationwide study
ObjectivesAlthough recent discoveries regarding the biomarkers of newborn screening (NBS) programs by tandem mass spectrometry (MS/MS) highlight the...
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Gene-centered metagenome analysis of Vulcano Island soil (Aeolian archipelago, Italy) reveals diverse microbial key players in methane, hydrogen and sulfur cycles
The Aeolian archipelago is known worldwide for its volcanic activity and hydrothermal emissions, of mainly carbon dioxide and hydrogen sulfide....
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T Helper Cells Producing Granulocyte-Macrophage Colony Stimulating Factor as a Risk Marker for Coronary Heart Disease
Coronary heart disease (CHD) is related to aberrant aggregation of immune cells in the plaques. This study focused on identification of abnormal T...
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Targeting SEZ6L2 in Colon Cancer: Efficacy of Bexarotene and Implications for Survival
BackgroundBexarotene, also recognized as Targretin, is categorized as a retinoid, a type of cancer drug. Nevertheless, the precise mechanisms of...
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Targeting cytotoxic lymphocyte antigen 4 (CTLA-4) in breast cancer
Breast cancer (BC) has a high mortality rate and is one of the most common malignancies in the world. Initially, BC was considered non-immunogenic,...
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Sex-related differences in left atrial substrate among patients with atrial fibrillation: evidence from high-density voltage map**
BackgroundThere is sufficient evidence that women with atrial fibrillation (AF) have a greater symptom burden than men with AF and are more likely to...
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Cohort study of prediction of venous thromboembolism in emergency department patients with extremity symptoms
Despite diagnostic algorithms, identification of venous thromboembolism (VTE) in emergency departments (ED) remains a challenge. We evaluated...
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Animal Models of Chronic Migraine: From the Bench to Therapy
Purpose of ReviewChronic migraine is a disabling progressive disorder without effective management approaches. Animal models have been developed and...
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The Study of the Effectiveness of Ethylmethylhydroxypyridine Succinate in Acute Alcohol Intoxication
The effectiveness of ethylmethylhydroxypyridine succinate (EMHPS) in acute alcohol intoxication was tested in a study on SPF male outbred ICR mice....
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Serotype distribution, antibiotic resistance, multilocus sequence ty**, and virulence factors of invasive and non-invasive Streptococcus pneumoniae in Northeast China from 2000 to 2021
Streptococcus pneumoniae infection is a major public health concern with high morbidity and mortality rates. This study aimed to evaluate the...
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Diabetic myonecrosis complicated by emphysematous pyomyositis and abscess caused by Escherichia coli: a case report
BackgroundNecrotizing myopathies and muscle necrosis can be caused by immune-mediated mechanisms, drugs, ischemia, and infections, and differential...
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Biologics or Janus Kinase Inhibitors in Rheumatoid Arthritis Patients Who are Insufficient Responders to Conventional Anti-Rheumatic Drugs
Rheumatoid arthritis (RA) is a chronic immune-mediated inflammatory disease which can induce progressive disability if not properly treated early....
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Diagnostic performance of CT/MRI LI-RADS v2018 in non-cirrhotic steatotic liver disease
ObjectiveTo assess the performance of computed tomography (CT)/magnetic resonance imaging (MRI) Liver Imaging Reporting and Data System (LI-RADS)...
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Bacteriophage therapy- a refurbished age-old potential strategy to treat antibiotic and multidrug resistant bacterial infections in future
The worldwide prevalence of antimicrobial resistance coupled with the unavailability of newer antibiotics, has brought the sharp focus back among the...
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More efficient adaptation of cardiovascular response to repeated restraint in spontaneously hypertensive rats: the role of autonomic nervous system
We hypothesized that sympathetic hyperactivity and parasympathetic insuficiency in spontaneously hypertensive rats (SHR) underlie their exaggerated...
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Response of Fusarium oxysporum soil isolate to amphotericin B and fluconazole at the proteomic level
Fusarium oxysporum is a cross-kingdom pathogen that infects humans, animals, and plants. The primary concern regarding this genus revolves around its...