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Decoding depression: a comprehensive multi-cohort exploration of blood DNA methylation using machine learning and deep learning approaches
The causes of depression are complex, and the current diagnosis methods rely solely on psychiatric evaluations with no incorporation of laboratory...
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Initiation of Alcohol Consumption Among the Tribal Male Adolescents in Dooars Region of West Bengal: A Failure Event Analysis Approach
BackgroundAlcohol consumption is a significant social and health problem among tribal male adolescents. The Dooars region of West Bengal has the...
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Study on the preventive effect of dexmedetomidine on anesthetic associated sleep disturbance in young to middle-aged female patients undergoing hysteroscopy: a study protocol for a crossover randomized controlled trial
BackgroundPostoperative sleep disturbance has a potentially detrimental effect on postoperative recovery. Perioperative patients are affected by...
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Assessment of the Psychological Effects on Firefighters in the Aftermath of the Pazarcik and Elbistan Earthquakes in 2023
In February 2023, two catastrophic earthquakes in Turkey resulted in over 50,000 fatalities and over 300,000 injuries. This study investigated the...
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Experiences participating in federal nutrition assistance programs during the early months of the COVID-19 pandemic: an investigation in Vermont
BackgroundFederal nutrition assistance programs serve as safety nets for many American households, and participation has been linked to increased...
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Challenges in the diagnosis and treatment of pure non-gestational uterine choriocarcinoma in a child: a case report
BackgroundDiagnosing non-gestational uterine choriocarcinoma in children is challenging because of its rarity and nonspecific imaging findings....
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YAP/TAZ interacts with RBM39 to confer resistance against indisulam
The Hippo pathway and its downstream effectors, Yes-associated protein/transcriptional coactivator with PDZ-binding motif (YAP/TAZ), are essential...
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The association between waist-to-hip ratio (WHR) with diabetes in the PERSIAN Guilan cohort study population
BackgroundWaist circumference (WC), or waist-to-hip ratio (WHR), potentially offers a more accurate reflection of intra-abdominal fat accumulation...
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Current trends and future perspectives in hadron therapy: radiobiology
PurposeThe purpose of this article was to highlight current and future trends in radiobiology in an effort to move hadron therapy forward through the...
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Consumer wearable devices for evaluation of heart rate control using digoxin versus beta-blockers: the RATE-AF randomized trial
Consumer-grade wearable technology has the potential to support clinical research and patient management. Here, we report results from the RATE-AF...
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Public health interventions to prevent children drowning: an updated systematic review
AimInjuries are a leading cause of death and disability for children and young people worldwide and a significant public health challenge. This...
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Ammonia exposure-triggered redox imbalance with the occurrence of inflammatory response, cell apoptosis, and the circadian clock disturbance leads to lung injury in growing pigs
The toxic impact of relatively low ammonia exposure on animal lungs lacks attention. Therefore, we employed pigs as an animal model to explore the...
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Current trends and future directions in internalized weight stigma research: a sco** review and synthesis of the literature
BackgroundSince the first papers focused on internalized weight stigma were published in the mid 2000’s, the literature has grown into a robust field...
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Knowledge, attitudes, and practices of Japanese physicians relating to climate change impacts on health, delivery of climate-specific advice, and advocacy for climate change policies
AimThis study aimed to assess the knowledge, attitudes, and practices (KAP) of physicians in Japan toward climate change and health, their delivery...
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HIV1 drug resistance among patients experiencing first-line treatment failure in Ethiopia: protocol for a systematic review and meta-analysis
BackgroundThe emergence of HIV drug resistance presents a substantial challenge. Current antiretroviral treatments, along with current classes, face...
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Synthetic datasets for open software development in rare disease research
BackgroundGlobally, researchers are working on projects aiming to enhance the availability of data for rare disease research. While data sharing...
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Efficacy of chemotherapy plus immune checkpoint inhibitors in patients with non-small cell lung cancer who have rare oncogenic driver mutations: a retrospective analysis
BackgroundTargeted therapy is now the standard of care in driver–oncogene-positive non-small cell lung cancer (NSCLC). Its initial clinical effects...