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Spores of Clostridioides difficile are toxin delivery vehicles
Clostridioides difficile causes a wide range of intestinal diseases through the action of two main cytotoxins, TcdA and TcdB. Ingested spores...
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Blood protein assessment of leading incident diseases and mortality in the UK Biobank
The circulating proteome offers insights into the biological pathways that underlie disease. Here, we test relationships between 1,468 Olink protein...
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Tracking cognitive trajectories in older survivors of COVID-19 up to 2.5 years post-infection
Emerging evidence suggests that neurological and other post-acute sequelae of COVID-19 can persist beyond or develop following SARS-CoV-2 infection....
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Nitric oxide brings innate immune resistance to M. tuberculosis infection among high-risk household contacts of pulmonary tuberculosis patients
Nitric oxide (NO) and iNOS are crucial host factors in innate immunity against intracellular pathogens. However, the role of NO in Mycobacterium...
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SETD8 inhibits apoptosis and ferroptosis of Ewing’s sarcoma through YBX1/RAC3 axis
Ewing’s sarcoma (ES) represents a rare yet exceedingly aggressive neoplasm that poses a significant health risk to the pediatric and adolescent...
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Temporal and spatial variation in the direct and indirect effects of climate on reproduction in alpine populations of Ranunculus acris L
Plant reproduction in alpine environments is affected by climate both directly through climate impacts on growth and phenology, and indirectly...
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Small Non-Coding sRNA53 Modulates the Quorum Sensing System to Enhance Drug Resistance in Escherichia coli Exposed to Heavy Ion and X-ray Irradiation
AbstractSmall non-coding RNAs (sRNAs, also called sncRNAs) known as gene expression regulatory factors are capable of modulating mRNA functions...
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Green synthesis of zinc oxide nanoparticles (ZnO-NPs) by Streptomyces baarnensis and its active metabolite (Ka): a promising combination against multidrug-resistant ESKAPE pathogens and cytotoxicity
Various eco-friendly techniques are being researched for synthesizing ZnO-NPs, known for their bioactivity. This study aimed at biosynthesizing...
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Dissolved organic matter released from beach wrack is source-specific and molecularly highly diverse
Beach wrack is an important supplier of nutrients and organic matter to sandy beach ecosystems and underlying subterranean estuaries (STEs),...
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Detection and molecular characterization of soft scale insect, Megapulvinaria maxima (Green) (Hemiptera: Coccidae) infesting Gymnema sylvestre (Retz.) R.Br. ex Sm. from India
Gymnema sylvestre (Retz.) R. Br. ex Sm is a vital medicinal plant effective in treatment of Diabetes mellitus. The soft scale, Megapulvinaria maxima (...
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ZBP1 condensate formation synergizes Z-NAs recognition and signal transduction
Z-DNA binding protein 1 (ZBP1) is a crucial player in the intracellular recognition of Z-form nucleic acids (Z-NAs) through its Zαβ domain,...
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Turbidity effects on prey consumption and survival of larval European smelt (Osmerus eperlanus)
The anadromous European smelt ( Osmerus eperlanus ) plays a key role in food webs of many riverine ecosystems in Europe. However, population sizes in...
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Genetic diversity studies of Baikal endemic sponges at the interspecies and population levels using high-resolution microsatellite markers
Lake Baikal, an ancient, massive lake in Siberia that holds 20% of the world’s fresh water reserves, is a unique center of speciation. Changes in the...
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Evaluating the probiotic effects of spraying lactiplantibacillus plantarum P-8 in neonatal piglets
BackgroundGut microbes play an important role in the growth and health of neonatal piglets. Probiotics can promote the healthy growth of neonatal...
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Habitat Suitability in High Andean Butterflies: The Role of Land Cover in the Occurrence and Conservation of Species
High Andean butterflies in northern South America are subject to landscape change processes. Our study used models to assess the habitat suitability...
