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Estimating and displaying population attributable fractions using the R package: graphPAF
Here we introduce graphPAF, a comprehensive R package designed for estimation, inference and display of population attributable fractions (PAF) and...
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Stage IA papillary and chromophobe renal cell carcinoma: effectiveness of cryoablation and partial nephrectomy
ObjectivesTo evaluate the effectiveness of cryoablation compared to partial nephrectomy in patients with stage IA papillary and chromophobe renal...
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Autophagy alterations in obesity, type 2 diabetes, and metabolic dysfunction-associated steatotic liver disease: the evidence from human studies
Autophagy is an evolutionarily conserved process that plays a pivotal role in the maintenance of cellular homeostasis and its impairment has been...
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The effect of transcranial alternating current stimulation on cognitive flexibility and attention of children with intellectual disability: a case report
BackgroundIntellectual disability is a neurodevelopmental disorder characterized by significant impairments in intellectual functioning and adaptive...
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Sample size calculation for data reliability and diagnostic performance: a go-to review
Sample size, namely the number of subjects that should be included in a study to reach the desired endpoint and statistical power, is a fundamental...
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Single-cell transcriptomic profiling of human pancreatic islets reveals genes responsive to glucose exposure over 24 h
Aims/hypothesisDisruption of pancreatic islet function and glucose homeostasis can lead to the development of sustained hyperglycaemia, beta cell...
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Higher fibre and lower carbohydrate intake are associated with favourable CGM metrics in a cross-sectional cohort of 470 individuals with type 1 diabetes
Aims/hypothesisThe aim of this work was to investigate the association between macronutrient intakes and continuous glucose monitoring (CGM) metrics...
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Exploring the shift in newborn care practices among mothers and grandmothers in rural Odisha, India — a qualitative study
BackgroundThis study delves into newborn care and infant-feeding practices in rural Odisha, specifically focusing on the rural KBK + region of Odisha...
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Cost avoidance of pharmacist-led deprescribing using STOPPFrail for older adults in nursing homes
BackgroundThe Screening Tool of Older Persons Prescriptions in Frail adults with limited life expectancy (STOPPFrail) criteria aim to reduce...
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Trajectories of BMI before and after diagnosis of type 2 diabetes in a real-world population
Aims/hypothesisFew studies have examined the clinical characteristics associated with changes in weight before and after diagnosis of type 2...
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Comparison of the clinical efficacy and prognosis of the two techniques for treating partial articular-sided supraspinatus tendon tears under arthroscopy
BackgroundAt present, shoulder arthroscopy is usually used for treatment of rotator cuff injuries. There is still debate over the precise technique...
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Effect of body mass index on 30-day complication rate and implant survival rate after simultaneous bilateral unicompartmental knee arthroplasty: a multicentre retrospective study
ObjectiveThe practice of simultaneous bilateral unicompartmental knee arthroplasty (SBUKA) remains a topic of debate, particularly in patients with...
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Causal relationship between bone mineral density and intervertebral disc degeneration: a univariate and multivariable mendelian randomization study
BackgroundAlthough previous studies have suggested a possible association between bone mineral density (BMD) and intervertebral disc degeneration...
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Establishment of an ovarian cancer exhausted CD8+T cells-related genes model by integrated analysis of scRNA-seq and bulk RNA-seq
Ovarian cancer (OC) was the fifth leading cause of cancer death and the deadliest gynecological cancer in women. This was largely attributed to its...
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Predictors of daytime blood pressure, nighttime blood pressure, and nocturnal dip** in patients with chronic kidney disease
Increasing attention has recently been paid to discrepancies between office and ambulatory blood pressure (BP) control in patients with chronic...
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Empagliflozin Effects in Patients with ST-Elevation Myocardial Infarction Undergoing Primary PCI: The EMI-STEMI Randomized Clinical Trial
IntroductionEmpagliflozin, a sodium-glucose cotransporter 2 (SGLT2) inhibitor, improves cardiovascular outcomes in heart failure patients, but data...
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Pitfalls of diagnosing pituitary hypoplasia in the patients with short stature
PurposeHeight age (HA) and bone age (BA) delay is well known in the patients with short stature. Therefore assessing pituitary hypoplasia based on...
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