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SUMOylation of nuclear receptor Nor1/NR4A3 coordinates microtubule cytoskeletal dynamics and stability in neuronal cells
BackgroundNor1/NR4A3 is a member of the NR4A subfamily of nuclear receptors that play essential roles in regulating gene expression related to...
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What to Measure in Aneurysmal Subarachnoid Haemorrhage Research—An International Delphi Survey
Aneurysmal subarachnoid haemorrhage (aSAH) is a devastating condition with high mortality and morbidity. The outcome measures used in aSAH clinical...
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Platelet-Rich Plasma Promotes the Expansion of Human Myoblasts and Favors the In Vitro Generation of Human Muscle Reserve Cells in a Deeper State of Quiescence
Stem cell therapy holds significant potential for skeletal muscle repair, with in vitro-generated human muscle reserve cells (MuRCs) emerging as a...
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Physiological and cellular mechanisms of ischemic preconditioning microRNAs-mediated in underlying of ischemia/reperfusion injury in different organs
Ischemia–reperfusion (I/R) injury, as a pathological phenomenon, takes place when blood supply to an organ is disrupted and then aggravated during...
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The Angiogenic Repertoire of Stem Cell Extracellular Vesicles: Demystifying the Molecular Underpinnings for Wound Healing Applications
Stem cells-derived extracellular vesicles (SC-EVs) have emerged as promising therapeutic agents for wound repair, recapitulating the biological...
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Key genes and molecular mechanisms related to Paclitaxel Resistance
Paclitaxel is commonly used to treat breast, ovarian, lung, esophageal, gastric, pancreatic cancer, and neck cancer cells. Cancer recurrence is...
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Aberrant telomeric structures and serum markers of telomere dysfunction in healthy aging: a preliminary study
Telomeres undergo a progressive shortening process as individuals age, and it has been proposed that severely shortened and dysfunctional telomeres...
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Unveiling the Role of Angiosperm Pollen Morphology in Attachment to the Moth (Lepidoptera) Proboscides
AbstractThe current study aims to understand the role of various morphological features of pollen grains in attachment with moth proboscides. To test...
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Sexual Size Dimorphism in Buthus tunetanus (Scorpiones: Buthidae) from Tunisia
AbstractScorpions are known to exhibit sexual size dimorphism, but data is still lacking from a large number of species throughout the world. Such...
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Identification of Tissue Expression Characteristics of Pig ALKBH5 and Its Association with Pathogenic Microbial Infection
AbstractN 6 -methyladenosine (m 6 A) as a reversible RNA modification has become a new direction and hotspot of RNA epigenetics research in the field of...
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Preclinical and clinical advances to overcome hypoxia in glioblastoma multiforme
Glioblastoma multiforme (GBM) is the most common adult primary brain tumor. The standard clinical treatment of GBM includes a maximal surgical...
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Growth Characteristics of 10 Deep-Sea Demersal Scorpaenoid Fish Species from the Arabian Sea: Insights for Database Update and Fisheries Management
AbstractThe present study provides length-weight relationships (LWRs) and condition factors (Kn) estimates for ten deep-sea scorpaeniform fishes...
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DNA Barcoding of Tree Frogs: Testing the Existence of Two Mitochondrial Lineages of Hyla savignyi
AbstractDNA barcoding is a popular approach that can aid in identifying species and has led to the discovery of many new amphibian species. In this...
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Dietary salt promotes cognitive impairment through repression of SIRT3/PINK1-mediated mitophagy and fission
Dietary salt is increasingly recognized as an independent risk factor for cognitive impairment. However, the exact mechanisms are not yet fully...
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Relationship between the severity of functional mitral regurgitation at admission and one-year outcomes in patients hospitalized for acute heart failure with mildly reduced ejection fraction
BackgroundThe epidemiological distribution of functional mitral regurgitation (FMR) in heart failure (HF) and mildly reduced ejection fraction...
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Age-related dysregulation of CXCL9/10 in monocytes is linked to impaired innate immune responses in a mouse model of Staphylococcus aureus osteomyelitis
BackgroundAge-associated impairments in innate immunity are believed to be a causative factor responsible for severe pathogenesis of Staphylococcus...
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Exploring secondary structures within the nuclear ribosomal DNA internal transcribed spacers (nr DNA ITS) for enhanced phylogenetic insights in Medicago sativa (alfalfa)
ITS sections, which are situated inside the ribosomal DNA operon, are recognized for their high levels of diversity and slow rate of evolution, which...
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Data-driven exploratory method investigation on the effect of dyslexia education at brain connectivity in Turkish children: a preliminary study
Dyslexia is a specific learning disability that is neurobiological in origin and is characterized by reading and/or spelling problems affecting the...
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Modelling Role of Protective and Nonprotective HLA Allele Inducing Different HIV Infection Outcomes
Human immunodeficiency virus (HIV) infects CD4+ cells and causes progressive immune function failure, and CD8+ cells lyse infected CD4+ cell via...
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DNA Methylation-derived biological age and long-term mortality risk in subjects with type 2 diabetes
BackgroundIndividuals with type 2 diabetes (T2D) face an increased mortality risk, not fully captured by canonical risk factors. Biological age...
