Search
Search Results
-
Altered RNA export by SF3B1 mutants confers sensitivity to nuclear export inhibition
SF3B1 mutations frequently occur in cancer yet lack targeted therapies. Clinical trials of XPO1 inhibitors, selinexor and eltanexor, in high-risk...
-
Doing a double take: when transthoracic echocardiography fails for mitral valve annuloplasty ring endocarditis with Streptococcus pyogenes: a case report
BackgroundThis case highlights several complications of a late and rare presentation of culture-negative Streptococcus pyogenes endocarditis of a...
-
Effectiveness of synthetic versus autologous bone grafts in foot and ankle surgery: a systematic review and meta-analysis
BackgroundAll orthopaedic procedures, comprising foot and ankle surgeries, seemed to show a positive trend, recently. Bone grafts are commonly...
-
Inhibitors of apolipoprotein C3, triglyceride levels, and risk of pancreatitis: a systematic review and meta-analysis
In recent years, novel apoC3 inhibitor therapies for the treatment of hypertriglyceridemia have been developed and assessed through phase II and III...
-
Emerging biologic augmentation strategies for meniscal repair: a systematic review
BackgroundMeniscal repair should be the gold standard. However, the meniscus is poorly vascularized and even an excellent meniscus repair may not...
-
Impact and effect of imaging referral guidelines on patients and radiology services: a systematic review
ObjectivesThe objective of this systematic review was to offer a comprehensive overview and explore the associated outcomes from imaging referral...
-
Relationship between the severity of functional mitral regurgitation at admission and one-year outcomes in patients hospitalized for acute heart failure with mildly reduced ejection fraction
BackgroundThe epidemiological distribution of functional mitral regurgitation (FMR) in heart failure (HF) and mildly reduced ejection fraction...
-
Comparative analysis of del Nido cardioplegia versus blood cardioplegia in isolate coronary artery bypass grafting
BackgroundThis study examined the efficacy of del Nido cardioplegia compared with traditional blood cardioplegia in adult cardiac surgery for...
-
Recognition of an extralobar pulmonary sequestration during lung resection
BackgroundExtralobar pulmonary sequestration is located outside the lung parenchyma and is covered by a separated pleural sac, which comprises...
-
Deep learning model based on endoscopic images predicting treatment response in locally advanced rectal cancer undergo neoadjuvant chemoradiotherapy: a multicenter study
PurposeNeoadjuvant chemoradiotherapy has been the standard practice for patients with locally advanced rectal cancer. However, the treatment response...
-
COVID-related constrictive pericarditis requiring pericardiectomy: a case report
BackgroundThe COVID-19 pandemic was primarily considered a respiratory malady in the early phases of the outbreak. However, as more patients suffer...
-
Diffusion-tensor magnetic resonance imaging as a non-invasive assessment of extracellular matrix remodeling in lumbar paravertebral muscles of rats with sarcopenia
BackgroundExtracellular matrix (ECM) remodeling in skeletal muscle is a significant factor in the development of sarcopenia. This study aims to...
-
The addition of mycoprotein to a mixed-meal impacts postprandial glucose kinetics without altering blood glucose concentrations: a randomised controlled trial
BackgroundMycoprotein is a high-fibre food previously shown to reduce postprandial glucose concentrations when ingested within a mixed-meal. We...
-
Stable Response and Sustained Improvement of Itch and Sleep Symptoms in Patients with Atopic Dermatitis Treated with Lebrikizumab over 52 Weeks
BackgroundLebrikizumab demonstrated significant improvement versus placebo for measures of skin clearance and patient-reported outcomes at weeks 16...
-
Association between body mass index and semen quality: a systematic review and meta-analysis
The continuous decline of human semen quality during the past decades has drawn much concern globally. Previous studies have suggested a link between...
-
An update to experimental and clinical aspects of tumor-associated macrophages in cancer development: hopes and pitfalls
Tumor-associated macrophages (TAMs) represent one of the most abundant tumor-infiltrating stromal cells, and their normal function in tumor...
-
Ultra-processed food consumption and risk of diabetes: results from a population-based prospective cohort
Aims/hypothesisUnderstanding the impact of the overall construct of ultra-processed foods on diabetes risk can inform dietary approaches to diabetes...
-
Implantable cardiac monitor and leadless pacemaker in the management of syncope due to intermittent high-degree atrioventricular block: a case report
BackgroundLead dislodgements, tricuspid valve failure, and wound infections are prominent issues addressed by leadless pacemakers (LPM). These...
-
Multiple lung abscesses and cold agglutinin syndrome following coronavirus disease 2019: a case report
BackgroundCold agglutination syndrome is a subtype of autoimmune hemolytic anemia. The condition is referred to as “cold” because the antibodies...
