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Glial cell transplant for brain diseases: the supportive saviours?
The incidence of brain diseases in humans is increasing as we experience a worldwide ageing of the population. Treatment for such diseases is still...
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Genetic association of lipid traits and lipid-related drug targets with normal tension glaucoma: a Mendelian randomization study for predictive preventive and personalized medicine
BackgroundGlaucoma is the leading cause of irreversible blindness worldwide. Normal tension glaucoma (NTG) is a distinct subtype characterized by...
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Explaining Socioeconomic Inequality in Psychological Well-being among Older People: A Comparison between Vietnam and Myanmar
Limited understanding exists regarding the social determinants of psychological well-being inequalities, particularly in develo** countries with...
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The Role of Prosocial Behaviour in the Deceleration of Conduct Problem Behaviour
While conduct problem behaviour initiated in early childhood often escalates in frequency and seriousness through adolescence, a notable deceleration...
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Changes in skeletal muscle function during chemotherapy and related factors in patients with acute leukemia
IntroductionSkeletal muscle function is an important prognostically relevant indicator in patients with acute leukemia (AL), but skeletal dysfunction...
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Elemental Diet as a Therapeutic Modality: A Comprehensive Review
Elemental diets have been employed for the management of various diseases for over 50 years, with several mechanisms mediating their beneficial...
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Ferroptosis – a potential feature underlying neratinib-induced colonic epithelial injury
PurposeNeratinib, a small-molecule tyrosine kinase inhibitor (TKI) that irreversibly binds to human epidermal growth factor receptors 1, 2 and 4...
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Assessing large language models’ accuracy in providing patient support for choroidal melanoma
PurposeThis study aimed to evaluate the accuracy of information that patients can obtain from large language models (LLMs) when seeking answers to...
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The AKT inhibitor AZD5363 elicits synthetic lethality in ARID1A-deficient gastric cancer cells via induction of pyroptosis
BackgroundGastric cancer (GC) is a deadly disease with poor overall survival and limited therapeutic options. Genetic alterations such as mutations...
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Brain volume and neurodevelopment at 13 years following sepsis in very preterm infants
BackgroundAssociations of neonatal infection with brain growth and later neurodevelopmental outcomes in very preterm (VP) infants are unclear. This...
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Low dose of dexamethasone combined with netupitant and palonosetron in preventing nausea and vomiting in breast cancer patients induced by anthracycline drugs
BackgroundTo study the effects of various courses of dexamethasone (DEX) combined with 5-HT3 receptor antagonists (RA) and NK-1 RA in suppressing...
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LncRNA ZFAS1 regulates ATIC transcription and promotes the proliferation and migration of hepatocellular carcinoma through the PI3K/AKT signaling pathway
PurposeLong noncoding RNAs (lncRNAs) exert a significant influence on various cancer-related processes through their intricate interactions with...
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The mediating role of systemic inflammation and moderating role of racialization in disparities in incident dementia
BackgroundExposure to systemic racism is linked to increased dementia burden. To assess systemic inflammation as a potential pathway linking exposure...
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Association of systemic and demographic risk factors with prevalence of retinopathy in US adults with prediabetes
Background/ObjectivesTo investigate the relative contribution of systemic risk factors to retinopathy in prediabetes using a nationally...
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ASO Visual Abstract: Open Versus Minimally Invasive Nephroureterectomy: Contemporary Analysis from a Wide National Population-Based Database
Contemporary trend analysis of a large national data set confirms the occurrence of a significant shift toward minimally invasive nephroureterectomy...
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Single Port Robotic Liver Resection: Metastasectomy for Recurrent Fibrolamellar Hepatocellular Carcinoma
BackgroundRobotic surgery has emerged as a promising approach for managing complex hepatic malignancies. This report presents a case of a single-port...
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Astrocytic Neuroligin-3 influences gene expression and social behavior, but is dispensable for synapse number
Neuroligin-3 ( Nlgn3 ) is an autism-associated cell-adhesion molecule that interacts with neurexins and is robustly expressed in both neurons and...
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The clinical value of artificial intelligence in assisting junior radiologists in thyroid ultrasound: a multicenter prospective study from real clinical practice
BackgroundThis study is to propose a clinically applicable 2-echelon (2e) diagnostic criteria for the analysis of thyroid nodules such that low-risk...
