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An Indigenous-informed sco** review study methodology: advancing the science of sco** reviews
BackgroundHistorically, Indigenous voices have been silent in health research, reflective of colonial academic institutions that privilege Western...
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Finite element simulation of treatment with locking plate for distal fibula fractures
An improved Finite Element Model(FEM) is applied to compare the biomechanical stability of plates with three different options in the treatment of...
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From traditional to transactional: exploration of khat use in Ethiopia through an interpretative phenomenological analysis
Khat, a naturally growing stimulant, has seen a significant increase in both consumption and cultivation in eastern Ethiopia. This reliance on khat...
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DBScope as a versatile computational toolbox for the visualization and analysis of sensing data from deep brain stimulation
Different neurostimulators for deep brain stimulation (DBS) come already with the ability to chronically sense local field potentials during...
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A dual-targeting approach with anti-IL10R CAR-T cells engineered to release anti-CD33 bispecific antibody in enhancing killing effect on acute myeloid leukemia cells
BackgroundImmunotherapies, including chimeric antigen receptor (CAR) T cells and bispecific antibodies (BsAbs), encounter several challenges in the...
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Circadian rhythm disruption upregulating Per1 in mandibular condylar chondrocytes mediating temporomandibular joint osteoarthritis via GSK3β/β-CATENIN pathway
BackgroundTemporomandibular joint osteoarthritis (TMJOA) has a high incidence rate, but its pathogenesis remains unclear. Circadian rhythm is an...
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Initiation of Alcohol Consumption Among the Tribal Male Adolescents in Dooars Region of West Bengal: A Failure Event Analysis Approach
BackgroundAlcohol consumption is a significant social and health problem among tribal male adolescents. The Dooars region of West Bengal has the...
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Study on the preventive effect of dexmedetomidine on anesthetic associated sleep disturbance in young to middle-aged female patients undergoing hysteroscopy: a study protocol for a crossover randomized controlled trial
BackgroundPostoperative sleep disturbance has a potentially detrimental effect on postoperative recovery. Perioperative patients are affected by...
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Fluorescence Studies on the Binding Affinity and Determination of Vitamin B12 in the Presence of Fibrinogen
The binding properties between vitamin B12 (vitB12, cyanocobalamin) and fibrinogen (Fib) were investigated by UV-vis absorption and...
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Current trends and future perspectives in hadron therapy: radiobiology
PurposeThe purpose of this article was to highlight current and future trends in radiobiology in an effort to move hadron therapy forward through the...
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Consumer wearable devices for evaluation of heart rate control using digoxin versus beta-blockers: the RATE-AF randomized trial
Consumer-grade wearable technology has the potential to support clinical research and patient management. Here, we report results from the RATE-AF...
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A nonoscillatory, millisecond-scale embedding of brain state provides insight into behavior
The most robust and reliable signatures of brain states are enriched in rhythms between 0.1 and 20 Hz. Here we address the possibility that the...
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Unlocking opioid neuropeptide dynamics with genetically encoded biosensors
Neuropeptides are ubiquitous in the nervous system. Research into neuropeptides has been limited by a lack of experimental tools that allow for the...
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The immunology of systemic lupus erythematosus
Understanding the pathogenesis and clinical manifestations of systemic lupus erythematosus (SLE) has been a great challenge. Reductionist approaches...
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Public health interventions to prevent children drowning: an updated systematic review
AimInjuries are a leading cause of death and disability for children and young people worldwide and a significant public health challenge. This...
