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Optimising a digitally delivered behavioural weight loss programme: study protocol for a factorial cluster randomised controlled trial
BackgroundDigitally delivered weight loss programmes can provide a convenient, potentially cheaper, and scalable treatment option for people who may...
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Factors influencing haulout behaviour of non-breeding weddell seals (Leptonychotes weddellii) at Cape Royds, Antarctica
The Weddell seal ( Leptonychotes weddellii ) is a fast-ice obligate species that plays an important role as both predator and prey within the...
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Scenario-based seismic hazard for horizontal and vertical ground motions in central Italy
We propose an innovative methodology for seismic emergency planning and earthquake risk mitigation in central Italy by integrating three prototypal...
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Progress and perspectives of metabolic biomarkers in human aortic dissection
BackgroundAortic dissection (AD) significantly threated human cardiovascular health, extensive clinical-scientific research programs have been...
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Synthesis of Carbon Dots via Microwave-Assisted Process: Specific Sensing of Fe(III) and Antibacterial Activity
Carbon dots synthesized from a renewable and sustainable source of biomass have greater attention in the nanomaterial research field. In the present...
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First Insight into the Phylogenetic Diversity of Bovicola caprae Infesting Goats of Different Agro-climatic Locations in India
Bovicola caprae is an important obligate ectoparasite of goats worldwide including India. The present study aimed at the molecular confirmation,...
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Glial cell transplant for brain diseases: the supportive saviours?
The incidence of brain diseases in humans is increasing as we experience a worldwide ageing of the population. Treatment for such diseases is still...
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Genetic association of lipid traits and lipid-related drug targets with normal tension glaucoma: a Mendelian randomization study for predictive preventive and personalized medicine
BackgroundGlaucoma is the leading cause of irreversible blindness worldwide. Normal tension glaucoma (NTG) is a distinct subtype characterized by...
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Home range overlaps of the brushtail possum (Trichosurus vulpecula): implications for disease transmission
Understanding how bovine tuberculosis (TB) is maintained in wildlife reservoirs is critical for the management of this disease impacting cattle in...
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Bedside electromyography for clinical assessment of sacral motor and reflex activity adapted for patients hospitalized with acute neurological conditions: a pilot study
Study designPilot cohort study.
ObjectiveTo develop and implement a sacral electromyographic (sEMG) technique at bedside to ascertain sparing of...
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The AKT inhibitor AZD5363 elicits synthetic lethality in ARID1A-deficient gastric cancer cells via induction of pyroptosis
BackgroundGastric cancer (GC) is a deadly disease with poor overall survival and limited therapeutic options. Genetic alterations such as mutations...
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Foraging for the future: traditional culinary uses of wild plants in the Western Himalayas–Kashmir Valley (India)
BackgroundIn the intricate tapestry of food security, wild food species stand as pillars, nourishing millions in low-income communities, and...
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Mesomelia-synostoses syndrome: contiguous deletion syndrome, SULF1 haploinsufficiency or enhancer adoption?
BackgroundMesomelia-Synostoses Syndrome (MSS)(OMIM 600,383) is a rare autosomal dominant disorder characterized by mesomelic limb shortening, acral...
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The clinical value of artificial intelligence in assisting junior radiologists in thyroid ultrasound: a multicenter prospective study from real clinical practice
BackgroundThis study is to propose a clinically applicable 2-echelon (2e) diagnostic criteria for the analysis of thyroid nodules such that low-risk...
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Effect of dipeptidyl peptidase-4 inhibitors on tumor necrosis factor alpha levels in patients with type 2 diabetes mellitus
AimsDipeptidyl peptidase-4 inhibitors (DPP-4i) served as oral antidiabetic agents for treatment of type 2 diabetes mellitus (T2DM). Although an...
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A novel simultaneous short-course nitrification, denitrification and fermentation process: bio-enhanced phenol degradation and denitrification in a single reactor
The feasibility of a simultaneous nitrification, denitrification and fermentation process (SNDF) under electric stirrer agitation conditions was...
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Fragile X Syndrome and FMR1 premutation: results from a survey on associated conditions and treatment priorities in Italy
Background and objectivesFragile X Syndrome (FXS) is the most common cause of inherited intellectual disability, caused by CGG-repeat expansions...
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Organic carbon-based amendments effectively reclaim post-tin mining site via modified soil organic carbon characteristics
PurposeThe complex process of post-mining land reclamation poses a great challenge in combatting land degradation and food insecurity. In this study,...
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KKL-35 inhibits growth of Staphylococcus aureus by systematically changing bacterial phenotypes
KKL-35 is a new oxadiazole compound with potent broad-spectrum antibacterial activity against a number of gram-positive and gram-negative bacteria....
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Reactive nitrogen species act as the enhancers of glutathione pool in embryonic axes of apple seeds subjected to accelerated ageing
Main conclusionReactive nitrogen species mitigate the deteriorative effect of accelerated seed ageing by affecting the glutathione concentration and...
