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Likelihood comparisons in bounded outcome score analysis must be internally consistent
Clinical trial endpoints are often bounded outcome scores (BOS), which are variables having restricted values within finite intervals. Common...
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Fabrication of Highly Sensitive and Selective Nitrite Colorimetric Sensor Based on the Enhanced Peroxidase Mimetic Activity of Using Acetic Acid Capped Zinc Oxide Nanosheets
Nitrite ions (NO 2 - ), as one of the leading type-A inorganic-anion, showing significant-effects in the aquatic environment and also to humans health....
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Gelatin/ CMC /HAP Nanocomposites Based on Double Micro-emulsion for Delivery of 5-FU: Synthesis and Chemical–Physical Characterization
In this study, G/CMC/HAP-based nanocomposite hydrogel is synthesized as a nanocarrier for the targeted delivery of 5-FU by double emulsion (W/O)...
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Silver Oxide Nanoparticles: A Promising Material with Melanin Modulatory Properties Validated in Drosophila
Silver oxide nanoparticles (Ag 2 O NPs) find enormous applications in electronics, industry, biomedical, pharmaceutical field, etc. In the present...
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Primary Human Cell-Derived Extracellular Matrix from Decellularized Fibroblast Microtissues with Tissue-Dependent Composition and Microstructure
PurposeHuman extracellular matrix (ECM) exhibits complex protein composition and architecture depending on tissue and disease state, which remains...
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Structural dynamics in chromatin unraveling by pioneer transcription factors
Pioneer transcription factors are proteins with a dual function. First, they regulate transcription by binding to nucleosome-free DNA regulatory...
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Microbial nanowires for sustainable electronics
Microbial protein nanowires are emerging as an alternative to abiotic nanowires for electronics applications. Microbial nanowires are sustainably...
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Polymeric Nanostructures Revolutionizing Cervical Cancer: Diagnostics, Therapeutics, and Theranostics
Cervical cancer is the fourth most common cancer among women. Despite recent advancements in diagnostics and therapeutics, this disease is still a...
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DNN-BP: a novel framework for cuffless blood pressure measurement from optimal PPG features using deep learning model
AbstractContinuous blood pressure (BP) provides essential information for monitoring one’s health condition. However, BP is currently monitored using...
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Cellular Traction Force Holds the Potential as a Drug Testing Readout for In Vitro Cancer Metastasis
IntroductionMetastasis is responsible for 90% of cancer-related deaths worldwide. However, the potential inhibitory effects of metastasis by various...
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Solid-state NMR assignment of α-synuclein polymorph prepared from helical intermediate
Synucleinopathies are neurodegenerative diseases characterized by the accumulation of α-synuclein protein aggregates in the neurons and glial cells....
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Applications of Advanced Nanomaterials in Biomedicine, Pharmaceuticals, Agriculture, and Food Industry
Nanotechnology has currently grown rapidly in various areas. Limiting particle size to the nanometer-scale changes the physical, optical, chemical,...
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Biofabrication of Cu/Cu2O-Nanoparticles and Exopolysaccharide of Azotobacter chroococcum XH2018 Based Nanobiofungicide and Its Characterization
The widespread occurrence of phytopathogenic fungi causes significant crop losses and poses a challenge for agricultural sustainability. Traditional...
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A dynamic flow fetal membrane organ-on-a-chip system for modeling the effects of amniotic fluid motion
Fetal membrane (amniochorion), the innermost lining of the intrauterine cavity, surround the fetus and enclose amniotic fluid. Unlike unidirectional...
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TYMS Knockdown Suppresses Cells Proliferation, Promotes Ferroptosis via Inhibits PI3K/Akt/mTOR Signaling Pathway Activation in Triple Negative Breast Cancer
Triple-negative breast cancer (TNBC) is characterized by a grim prognosis and numerous challenges. The objective of our study was to examine the role...
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Reduced actual vapor pressure exerts a significant influence on maize yield through vapor pressure deficit amid climate warming
Understanding the impact of climate warming on crop yield and its associated mechanisms is paramount for ensuring food security. Here, we conduct a...
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Clothing color effect as a target of the smallest scale climate change adaptation
The purpose of this study is to understand a physical mechanism to determine the surface temperature of clothes in calm and fine conditions of...
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Heat and Mass Transfer Analysis of MHD Squeezing Flow of Sodium Alginate-Based Casson Hybrid Nanofluid with Chemical Reaction and Thermal Resistive Effects
The unsteady magnetohydrodynamics (MHD) flow and radiative thermal transfer of viscous and Casson hybrid nanofluid through two surfaces in a...
