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LAFeBS, alive, kicking, and growing: the story continues…
This Commentary describes a call for contributions to an upcoming Special Issue (SI) of Biophysical Reviews on the Latin American Federation of...
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Intratumoral Delivery of Genetically Engineered Anti-IL-6 Trans-signaling Therapeutics
Interleukin-6 (IL-6) is a highly pro-inflammatory cytokine involved in the etiopathology of several inflammatory diseases and cancer. As so, the...
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Terrestrial laser scanning and low magnetic field digitization yield similar architectural coarse root traits for 32-year-old Pinus ponderosa trees
BackgroundUnderstanding how trees develop their root systems is crucial for the comprehension of how wildland and urban forest ecosystems plastically...
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Flexible multitask computation in recurrent networks utilizes shared dynamical motifs
Flexible computation is a hallmark of intelligent behavior. However, little is known about how neural networks contextually reconfigure for different...
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A vagal–brainstem interoceptive circuit for cough-like defensive behaviors in mice
Coughing is a respiratory behavior that plays a crucial role in protecting the respiratory system. Here we show that the nucleus of the solitary...
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Microglia are dispensable for experience-dependent refinement of mouse visual circuitry
To test the hypothesized crucial role of microglia in the developmental refinement of neural circuitry, we depleted microglia from mice of both sexes...
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Deep migration learning-based recognition of diseases and insect pests in Yunnan tea under complex environments
BackgroundThe occurrence, development, and outbreak of tea diseases and pests pose a significant challenge to the quality and yield of tea,...
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Proteome-scale tagging and functional screening in mammalian cells by ORFtag
The systematic determination of protein function is a key goal of modern biology, but remains challenging with current approaches. Here we present...
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Microsecond time-resolved X-ray scattering by utilizing MHz repetition rate at second-generation XFELs
Detecting microsecond structural perturbations in biomolecules has wide relevance in biology, chemistry and medicine. Here we show how MHz repetition...
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Sexually dimorphic oxytocin circuits drive intragroup social conflict and aggression in wild house mice
In nature, both males and females engage in competitive aggressive interactions to resolve social conflicts, yet the behavioral principles guiding...
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EAF2 Downregulation Recruits Tumor-associated Macrophages in Prostate Cancer through Upregulation of MIF
BackgroundThe role of tumor inflammatory microenvironment in the advancement of cancer, particularly prostate cancer, is widely acknowledged....
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Molecular Characterization of Lineage-IV Peste Des Petits Ruminants Virus and the Development of In-House Indirect Enzyme-Linked Immunosorbent Assay (IELISA) for its Rapid Detection”
Peste des petits ruminants (PPRV), a highly contagious viral disease, causes significant economic losses concerning sheep and goats. Recently, PPR...
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