Search
Search Results
-
Understand the Stabilization Engineering of Ascorbic Acid, Map** the Scheme for Stabilization, and Advancement.
AbstractVitamin C is extensively used in cosmetic formulation, howbeit stability is the supreme demerit that limits its use in beautifying products....
-
Luteolin Mitigates D-Galactose-Induced Brain Ageing in Rats: SIRT1-Mediated Neuroprotection
Luteolin is an essential natural polyphenol found in a variety of plants. Numerous studies have supported its protective role in neurodegenerative...
-
Tomatidine, a Steroidal Alkaloid, Synergizes with Cisplatin to Inhibit Cell Viability and Induce Cell Death Selectively on FLT3-ITD+ Acute Myeloid Leukemia Cells
BackgroundAcute Myeloid Leukemia (AML) is a hematological cancer that frequently presents with a range of side effects and drug resistance during...
-
The Impact of the VEGF/VEGFR2/PI3K/AKT Signaling Axis on the Proliferation and Migration Abilities of Human Dental Pulp Stem Cells
The potential therapeutic benefits of human dental pulp stem cells (HDPSCs) in dental regenerative medicine have been demonstrated. However, little...
-
-
Knockout Transporter Cell Lines to Assess Substrate Potential Towards Efflux Transporters
P-glycoprotein (P-gp), breast cancer resistance protein (BCRP) and multidrug resistance transporter 2 (MRP2) are efflux transporters involved in the...
-
A Comprehensive on Synthesis and Antimicrobial Evaluation of Substituted-Arylideneamino-5-(5-Chlorobenzofuran-2-yl)-1, 2, 4-Triazole-3-Thiol Derivatives/ Schiff Bases
Schiff bases are well known and popular classes of organic compounds containing imine (R 2 C = NH) group that are widely used as catalysts and...
-
Dysregulated Wnt/β-catenin signaling confers resistance to cuproptosis in cancer cells
Cuproptosis is characterized by the aggregation of lipoylated enzymes of the tricarboxylic acid cycle and subsequent loss of iron-sulfur cluster...
-
Elucidating CTLA-4’s role in tumor immunity: a comprehensive overview of targeted antibody therapies and clinical developments
Cytotoxic T-lymphocyte-associated antigen 4 (CTLA-4) emerges as a key single-chain transmembrane glycoprotein predominantly expressed in effector T...
-
Facile preparation of Ni-Hg-Fe amalgam for hydrogen evolution reaction in NaOH solution
An alloy of Ni-Hg-Fe was synthesized on a graphite electrode using direct current electrodeposition to facilitate the hydrogen evolution reaction...
-
Synthesis, Characterization, Phytochemistry, and Therapeutic Potential of Azadirachta indica Conjugated Silver Nanoparticles: A Comprehensive Study on Antidiabetic and Antioxidant Properties
Nanotechnology has become a major topic of study, particularly in the medical and health domains. Because nanomedicine has a higher recovery rate...
-
Identification of potential natural product derivatives as CK2 inhibitors based on GA-MLR QSAR modeling, synthesis and biological evaluation
Protein kinase CK2 is a validated target for cancer therapy. Many natural products have shown inhibitory activity against CK2 as potential...
-
Bexagliflozin: a comprehensive review of a recently approved SGLT2 inhibitor for the treatment of type 2 diabetes mellitus
Type 2 diabetes mellitus (T2DM) remains a major global health threat, claiming millions of lives annually. Despite recent advancements in managing...
-
Influence of Suppressor of Cytokine Signaling 1 (SOCS1) Gene Variations on Polycystic Ovary Syndrome
Polycystic ovarian syndrome (PCOS) is associated with low-grade systemic inflammation and an increase in inflammation markers, which are crucial in...
-
Investigating the Impact of Intracerebroventricular Streptozotocin on Female Rats with and without Ovaries: Implications for Alzheimer’s Disease
To contribute to research on female models of Alzheimer’s disease (AD), our aim was to study the effect of intracerebroventricular (ICV) injection of...
-
Synthesis of two Fluorescent Complexes and Their use as Multifunctional Nanomedicine Carriers for Rhabdomyosarcoma Treatment
This study focuses on the design and synthesis of two novel coordination polymers (CPs), named 1 and 2 , with excellent fluorescent properties. Their...
-
Accuracy of prediction from multi-environment trials for new locations using pedigree information and environmental covariates: the case of sorghum (Sorghum bicolor (L.) Moench) breeding
Key messagesWe investigate a method of extracting and fitting synthetic environmental covariates and pedigree information in multilocation trial data...
-
Unveiling the mechanism of essential oil action against skin pathogens: from ancient wisdom to modern science
Essential oils are among the most well-known phyto-compounds, and since ancient times, they have been utilized in medicine. Over 100 essential oils...
