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The impact of national savings on economic development: a focused study on the ten poorest countries in Sub-Saharan Africa
The purpose of this study is to examine the impact of national savings on economic development, as measured by the Human Development Index (HDI),...
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Evaluation of smear layer and Ca/P ratio in intra-radicular dentine irrigated with different irrigants adjunct with diode laser
BackgroundThis study aims to determine the smear layer removal from the root canals using different irrigant solutions with diode laser.
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Whole genome sequencing refines stratification and therapy of patients with clear cell renal cell carcinoma
Clear cell renal cell carcinoma (ccRCC) is the most common form of kidney cancer, but a comprehensive description of its genomic landscape is...
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Large-scale 2D heterostructures from hydrogen-bonded organic frameworks and graphene with distinct Dirac and flat bands
The current strategies for building 2D organic-inorganic heterojunctions involve mostly wet-chemistry processes or exfoliation and transfer, leading...
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Investigation of [11C]carfentanil for mu opioid receptor quantification in the rat brain
[ 11 C]Carfentanil ([ 11 C]CFN) is the only selective carbon-11 labeled radiotracer currently available for positron emission tomography (PET) imaging of...
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Differential expression of “Candidatus Liberibacter solanacearum” genes and prophage loci in different life stages of potato psyllid
Psyllid species, including the potato psyllid (PoP) Bactericera cockerelli (Sulc) (Triozidae) serve as host and vector of “ Candidatus Liberibacter...
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Analytical realization of complex thermal meta-devices
Fourier’s law dictates that heat flows from warm to cold. Nevertheless, devices can be tailored to cloak obstacles or even reverse the heat flow....
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Beta activity in human anterior cingulate cortex mediates reward biases
The rewards that we get from our choices and actions can have a major influence on our future behavior. Understanding how reward biasing of behavior...
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Adenine base editing-mediated exon skip** restores dystrophin in humanized Duchenne mouse model
Duchenne muscular dystrophy (DMD) affecting 1 in 3500–5000 live male newborns is the frequently fatal genetic disease resulted from various mutations...
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A combination treatment based on drug repurposing demonstrates mutation-agnostic efficacy in pre-clinical retinopathy models
Inherited retinopathies are devastating diseases that in most cases lack treatment options. Disease-modifying therapies that mitigate pathophysiology...
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High amphipathicity of α-helical peptides enhances unmethylated CpG DNA-induced activation of mouse macrophage-like RAW264.7 cells
The α-helical antimicrobial peptide Kn2-7 enhances the activation of mouse macrophage-like RAW264.7 induced by DNA containing unmethylated...
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Fibroblast growth factor 23 inhibition attenuates steroid-induced osteonecrosis of the femoral head through pyroptosis
Steroid-induced osteonecrosis of the femoral head (SONFH) is the predominant cause of non-traumatic osteonecrosis of the femoral head (ONFH)....
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The SIRT2-AMPK axis regulates autophagy induced by acute liver failure
This study explores the role of SIRT2 in regulating autophagy and its interaction with AMPK in the context of acute liver failure (ALF). This study...
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Evaluating psychological distress associated with life events under the traumatic experience threshold in patients with major depressive and bipolar disorder
Patients with bipolar disorder (BD) and major depressive disorder (MDD) experience psychological distress associated with daily events that do not...
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Modeling and self-supporting printing simulation of fuse filament fabrication
This study presented a comprehensive computational fluid dynamics-based model for fused filament fabrication (FFF) three-dimensional (3D) printing...
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Engineered reversible inhibition of SpyCatcher reactivity enables rapid generation of bispecific antibodies
The precise regulation of protein function is essential in biological systems and a key goal in chemical biology and protein engineering. Here, we...
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Single-cell total-RNA profiling unveils regulatory hubs of transcription factors
Recent development of RNA velocity uses master equations to establish the kinetics of the life cycle of RNAs from unspliced RNA to spliced RNA (i.e.,...
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Pre-IVM with C-type natriuretic peptide promotes mitochondrial biogenesis of bovine oocytes via activation of CREB
The aim of this study was to evaluate the effects of C-type natriuretic peptide (CNP) treatment prior to in vitro maturation (IVM) on mitochondria...
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Threat-induced prosocial behavior: enhanced exogenous attention to protect others from harm
As social animals, humans tend to voluntarily engage in pro-social behavior to prevent harm to others. However, to what extent prosocial behavior can...
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AI-NERD: Elucidation of relaxation dynamics beyond equilibrium through AI-informed X-ray photon correlation spectroscopy
Understanding and interpreting dynamics of functional materials in situ is a grand challenge in physics and materials science due to the difficulty...
