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Comparative genomic and transcriptomic analyses reveal distinct response strategies to hypoxia by Vibrio parahaemolyticus isolates of clinical and aquatic animal origins
PurposeVibrio parahaemolyticus is a leading seafood borne pathogen worldwide. The aim of this study was to decipher the response mechanism of V....
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Lactobacilli Have an Opposite Effect on the Resistance to Oxidative Damage of HPV-Infected Compared with Uninfected Vaginal Epithelial Cells
To study how indigenous or probiotic-introduced lactobacilli affect the sensitivity (estimated as the proportion of surviving, apoptotic, and...
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Transcriptomic and metabolomic analysis of prebiotics utilization by Bifidobacterium animalis
In this study, the utilization mechanism of oligosaccharides by Bifidobacterium was investigated through the transcriptome sequencing and...
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The role of bacterial metabolism in human gut colonization
Can we anticipate the emergence of the next pandemic antibiotic-resistant bacterial clone? Addressing such an ambitious question relies on our...
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Candida auris central line-associated blood stream infection in critically ill patients: the worst end of a bad scenario
BackgroundCandida auris ( C. auris ) is an emerging aggressive pathogen that causes severe infections in critically ill patients. Therefore, the...
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Rational construction of a high-quality and high-efficiency biosynthetic system and fermentation optimization for A82846B based on combinatorial strategies in Amycolatopsis orientalis
BackgroundOritavancin is a new generation of semi-synthetic glycopeptide antibiotics against Gram-positive bacteria, which served as the first and...
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Characteristics and kinetics of thermophilic actinomycetesʼ amylase production on agro-wastes and its application for ethanol fermentation
Thermophilic actinomycetes are commonly found in extreme environments and can thrive and adapt to extreme conditions. These organisms exhibit...
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Cognitive and Emotional Effect of a Multi-species Probiotic Containing Lactobacillus rhamnosus and Bifidobacterium lactis in Healthy Older Adults: A Double‐Blind Randomized Placebo‐Controlled Crossover Trial
As the population ages, cognitive decline becomes more common. Strategies targeting the gut-brain axis using probiotics are emerging to achieve...
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A novel Enterococcus faecalis bacteriophage Ef212: biological and genomic features
This study aimed to isolate and characterize biological and genomic features of a phage infecting Enterococcus faecalis . The phage was isolated from...
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From DNA to lytic proteins: transcription and translation of the bacteriophage T5 holin/endolysin operon
The analysis of transcriptional activity of the bacteriophage T5 hol/endo operon conducted in the paper revealed a strong constitutive promoter...
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The phosphate-solubilising fungi in sustainable agriculture: unleashing the potential of fungal biofertilisers for plant growth
Phosphate-solubilising fungi (PSF) are beneficial microorganisms that play a pivotal role in plant growth by increasing the availability of...
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A meta-analysis of semiconductor materials fabricated in microgravity
This meta-analysis of 160 semiconductor crystals that were grown in microgravity on orbital vehicles between 1973 and 2016 is based on publicly...
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Increased stable integration efficiency in CHO cells through enhanced nuclear localization of Bxb1 serine integrase
BackgroundMammalian display is an appealing technology for therapeutic antibody development. Despite the advantages of mammalian display, such as...
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Engineering strategies for enhanced 1′, 4′-trans-ABA diol production by Botrytis cinerea
BackgroundCurrently, industrial fermentation of Botrytis cinerea is a significant source of abscisic acid (ABA). The crucial role of ABA in plants...
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Chemical fingerprint analysis of fermented Morinda citrifolia L. (Noni) juice by UHPLC Q-TOF/MS combined with chemometric analysis
Morinda citrifolia L. (Noni) has been widely used in traditional medicine in tropical zones and has become increasingly popular globally owing to its...
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The effect of L-cysteine on starch and protein degradation during barley germination
ObjectivesIn order to investigate the impact of L-cysteine (L-Cys) on starch and protein degradation during barley germination. The amylase...
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Alleviation of heavy metals chromium, cadmium and lead and plant growth promotion in Vigna radiata L. plant using isolated Pseudomonas geniculata
Plants exposed to heavy metals (HMs) stress negatively affect their development and production capacity. Chromium (Cr), Cadmium (Cd), and Lead (Pb)...
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Recent advances in lycopene and germacrene a biosynthesis and their role as antineoplastic drugs
Sesquiterpenes and tetraterpenes are classes of plant-derived natural products with antineoplastic effects. While plant extraction of the...
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Synthesis of metformin-derived fluorescent quantum dots: uptake, cytotoxicity, and inhibition in human breast cancer cells through autophagy pathway
BackgroundBreast cancer remains a challenge for physicians. Metformin, an antidiabetic drug, show promising anticancer properties against cancers. An...
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Production and characterization of extracellular liamocins produced from fungal strains of Aureobasidium spp.
Liamocins, a group of high-density glycolipids, are only produced by certain strains of the yeast-like fungi in the genus Aureobasidium . Until now,...