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Genomic representativeness and chimerism in large collections of SAGs and MAGs of marine prokaryoplankton
BackgroundSingle amplified genomes (SAGs) and metagenome-assembled genomes (MAGs) are the predominant sources of information about the coding...
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Impact on Glycemia Risk Index and other metrics in type 1 adult patients switching to Advanced Hybrid Closed-Loop systems: a one-year real-life experience
BackgroundAdvanced Hybrid Closed-Loop system (AHCL) has profoundly changed type 1 diabetes therapy. This study primarily aimed to assess the impact...
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Gene therapy by virus-like self-spooling toroidal DNA condensates for revascularization of hindlimb ischemia
Peripheral arterial diseases (PAD) have been reported to be the leading cause for limb amputations, and the current therapeutic strategies including...
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Biofortification of Triticum species: a step** stone to combat malnutrition
BackgroundBiofortification represents a promising and sustainable strategy for mitigating global nutrient deficiencies. However, its successful...
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Synergistic effects of melatonin and 24-epibrassinolide on chickpea water deficit tolerance
BackgroundWater deficiency stress reduces yield in grain legumes, primarily due to a decrease in the pods number. Melatonin (ML) and...
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ESF1 and MIPEP proteins promote estrogen receptor-positive breast cancer proliferation and are associated with patient prognosis
BackgroundEstrogen receptor-positive (ER+) breast cancer accounts for two-thirds of all breast cancers, and its early and late recurrences still...
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Potato Yield Classification Using Weather Variables: a Discriminant Analysis Approach
The study aims to develop a multivariate statistical model to classify potato yield based on weather variables. The potato yields of India from years...
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Unraveling the differential mechanisms of revascularization promoted by MSCs & ECFCs from adipose tissue or umbilical cord in a murine model of critical limb-threatening ischemia
BackgroundCritical limb-threatening ischemia (CLTI) constitutes the most severe manifestation of peripheral artery disease, usually induced by...
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Examining the determinants of food waste behavior in China at the consumer level
Food loss and waste are global problems for food security, as one-third of all food produced globally does not reach the consumer’s table. These...
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Post-implantation analysis of genomic variations in the progeny from develo** fetus to birth
The analysis of genomic variations in offspring after implantation has been infrequently studied. In this study, we aim to investigate the extent of de...
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Exploring the challenges of RNAi-based strategies for crop protection
RNA silencing (or RNA interference, RNAi) initiated by double-stranded RNAs is a conserved mechanism for regulating gene expression in eukaryotes....
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Transcriptome analysis of the degradation process of organic nitrogen by two heterotrophic nitrifying and aerobic denitrifying bacteria
The heterotrophic nitrification aerobic denitrification bacteria (HNDS) can perform nitrification and denitrification at the same time. Two HNDS...
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BACH2 regulates diversification of regulatory and proinflammatory chromatin states in TH17 cells
Interleukin-17 (IL-17)-producing helper T (T H 17) cells are heterogenous and consist of nonpathogenic T H 17 (npT H 17) cells that contribute to tissue...
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Intracellular domain of epithelial cell adhesion molecule induces Wnt receptor transcription to promote colorectal cancer progression
BackgroundEpithelial cell adhesion molecule (EpCAM) has been widely studied as a tumor antigen due to its expression in varieties of solid tumors....
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Vitamin C inactivates c-Jun N-terminal kinase to stabilize heart and neural crest derivatives expressed 1 (Hand1) in regulating placentation and maintenance of pregnancy
Vitamin C (VC) serves as a pivotal nutrient for anti-oxidation process, metabolic responses, and stem cell differentiation. However, its precise...
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Comparison of drying methods for biochemical composition, energy aspects, and color properties of alfalfa hay
Alfalfa is a crucial feed source for livestock, necessitating proper drying to achieve optimal moisture levels before consumption. This study aims to...