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Frequency of use and characterization of frailty assessments in observational studies on older women with breast cancer: a systematic review
BackgroundBreast cancer and frailty frequently co-occur in older women, and frailty status has been shown to predict negative health outcomes....
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Centenarians, semi and supercentenarians, COVID-19 and Spanish flu: a serological assessment to gain insight into the resilience of older centenarians to COVID-19
BackgroundAlthough it is well known that the older people have been the most susceptible to COVID-19, there are conflicting data on the...
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Understanding and alleviating informal caregiver burden through the development and validation of a caregiver strain index-based model in Taiwan
BackgroundQuantifying the informal caregiver burden is important for understanding the risk factors associated with caregiver overload and for...
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Detecting agitation and aggression in persons living with dementia: a systematic review of diagnostic accuracy
Objective40–60% of persons living with dementia (PLWD) experience agitation and/or aggression symptoms. There is a need to understand the best method...
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The role of social network diversity in self-perceptions of aging in later life
While the link between self-perceptions of aging (SPA) and healthy aging is well established, less is known about the association between social...
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Adoptive NK cell therapy: a potential revolutionary approach in longevity therapeutics
The aging process intricately involves immune system dynamics, with a crucial role in managing senescent cells (SNCs) and their senescence-associated...
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Perceived but not objective measures of neighborhood safety and food environments are associated with longitudinal changes in processing speed among urban older adults
BackgroundAlthough a growing body of literature documents the importance of neighborhood effects on late-life cognition, little is known about the...
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Polypharmacy and drug interactions in older patients with cancer receiving chemotherapy: associated factors
BackgroundPolypharmacy in older adults with cancer receiving chemotherapy leads to increased risks of drug interactions, translating in potential...
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Addressing loneliness and social isolation through the involvement of primary and secondary informal caregivers in nursing homes: a sco** review
ObjectivesTo clarify the mechanisms of interventions addressing loneliness and social isolation in older adults living in nursing homes through the...
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Association of potentially inappropriate medications with prognosis among older patients with non-small cell lung cancer
BackgroundPotentially inappropriate medications (PIMs) are common among older adults with cancer, but their association with overall survival (OS)...
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A simple machine learning model for the prediction of acute kidney injury following noncardiac surgery in geriatric patients: a prospective cohort study
BackgroundSurgery in geriatric patients often poses risk of major postoperative complications. Acute kidney injury (AKI) is a common complication...
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Providing and receiving support through a tailor-made mobile app: a qualitative study on experience of professionals and family caregivers to persons with dementia
BackgroundThe ageing population and the rise of persons with dementia (PWD) living at home have increased the need for support by family caregivers...
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Potential profiling of self-management skills in older co-morbid patients
BackgroundUnder the general trend of global aging, geriatric comorbidity is increasingly common, which may have some impact on the quality of life of...
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Measuring pain intensity in older patients: a comparison of five scales
Background and aimsPain is common in older individuals. In order to understand and treat pain in this group, reliable and valid measures are needed....
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Single cell transcriptome analysis identified a unique neutrophil type associated with Alzheimer’s disease
BackgroundNeutrophils play an essential role in Alzheimer’s disease (AD) pathology. However, the extent of their heterogeneity remains poorly...
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Development of machine learning models for patients in the high intrahepatic cholangiocarcinoma incidence age group
BackgroundIntrahepatic cholangiocarcinoma (ICC) has a poor prognosis and is understudied. Based on the clinical features of patients with ICC, we...
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Altered pupil light and darkness reflex and eye-blink responses in late-life depression
BackgroundLate-life depression (LLD) is a prevalent neuropsychiatric disorder in the older population. While LLD exhibits high mortality rates,...
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A Phenomenological Analysis of Emerging Adults’ Social Group Disruptions
Emerging adults experience the highest rates of loneliness and mental health issues of any age group. Given that frequent changes to their social...
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Development of a real-world simulated instrument for evaluating visuospatial working memory: a preliminary psychometric study on older adults
BackgroundA prevalent challenge in neuropsychological assessment, particularly when utilizing instruments designed for controlled laboratory...
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The impact of cognitive-motor interference on balance and gait in hearing-impaired older adults: a systematic review
BackgroundHearing impairments are a rising burden in our aging society. Hearing loss is associated with reduced cognitive performance as well as...
