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Proinflammatory Activation of Monocytes in Patients with Immunoinflammatory Rheumatic Diseases
AbstractThe pathogenesis of immunoinflammatory rheumatic diseases (IRDs) is based on chronic inflammation, one of the key mechanisms of which may be...
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The Prevalence and Factors Associated with Coronary Heart Disease in Patients with Gout
AbstractGout is associated with increased risk of cardiovascular disease (CVD) morbidity and mortality. Therefore, an association between coronary...
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Induction of the PERK-eIF2α-ATF4 Pathway in M1 Macrophages under Endoplasmic Reticulum Stress
AbstractTranslation inhibition can activate two cell death pathways. The first pathway is activated by translational aberrations, the second by...
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Maize hybrids response to limited nitrogen under current and future CO2 environments
Given the increased nitrogen fertilization, rise in fertilizer prices, and atmospheric CO 2 levels, it is crucial to understand how crops respond to...
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Production of a bacterial secretome highly efficient for the deconstruction of xylans
Bacteria within the Paenibacillus genus are known to secrete a diverse array of enzymes capable of breaking down plant cell wall polysaccharides. We...
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Biophysical characterization of the phase separation of TDP-43 devoid of the C-terminal domain
BackgroundFrontotemporal lobar degeneration with ubiquitin-positive inclusions (FTLD-TDP), amyotrophic lateral sclerosis (ALS) and limbic-predominant...
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Lnc PVT1 facilitates TGF-β1-induced human cardiac fibroblast activation in vitro and ISO-induced myocardial fibrosis in vivo through regulating MYC
Cardiac fibrosis is a commonly seen pathophysiological process in various cardiovascular disorders, such as coronary heart disorder, hypertension,...
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Epigenome editing: a novel perspective towards ensuring global food security
The fact that the human population is projected to cross the mark of staggering 8.3 billion by the year 2030 has raised the serious concerns to...
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Basic Fibroblast Growth Factor Accumulation in Culture Medium Masks the Direct Antitumor Effect of Anti-VEGF Agent Bevacizumab
AbstractThe direct antitumor effect of bevacizumab (BEV) has long been debated. Evidence of the direct antitumor activities of drugs are mainly...
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Biodiversity of Epibenthic Invertebrates in the Subtidal Mekong Estuaries, Southern Vietnam with Remarks on Decapod Assemblages
AbstractEpibenthic invertebrates in three estuaries of the Mekong River, namely Co Chien, Ba Lai, and Cua Dai, were sampled for ecological analysis...
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Phylogenetic Inference from 16S rRNA Gene Sequencing in Chromosome Races of the Genus Nannospalax Species (Rodentia: Spalacidae)
AbstractIn this study, we aimed to develop a species-level phylogeny for the Nannospalax genus, identify cryptic species that are difficult to...
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Rutin Ameliorates Toxoplasma gondii-Induced Brain Tissue Damage via Inhibiting P2X7R/NLRP3 Pro-Inflammatory and Enhancing PI3K/AKT/Nrf2/HO-1 Antioxidant Signaling Pathway
AbstractBain damage caused by Toxoplasma gondii ( T. gondii ) is associated with increased inflammatory response and oxidative stress. Rutin, a...
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Enhancing broiler chicken health and performance: the impact of phytobiotics on growth, gut microbiota, antioxidants, and immunity
The total ban on antibiotics as growth promoters in livestock nutrition, introduced in EU (European Union) countries on 1 January 2006, presented...
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Fine map** of interspecific secondary CSSL populations revealed key regulators for grain weight at qTGW3.1 locus from Oryza nivara
Grain weight (GW) is the most important stable trait that directly contributes to crop yield in case of cereals. A total of 105 backcross...
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The Effect of Oxidative Stress and Antioxidants Treatment on Gestational Diabetes Mellitus Outcome: A Sco** Review
Diagnosing a pregnant woman’s glucose intolerance is referred to as gestational diabetes mellitus (GDM). Diabetes has been linked to enhanced...
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The influence of sex-specific factors on biological transformations and health outcomes in aging processes
The aging process demonstrates notable differences between males and females, which are key factors in disease susceptibility and lifespan. The...
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GPR116 alleviates acetaminophen-induced liver injury in mice by inhibiting endoplasmic reticulum stress
BackgroundAcetaminophen (APAP) overdose is a significant contributor to drug-induced liver injury worldwide. G-protein–coupled receptor 116 (GPR116)...
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The eEF2 kinase coordinates the DNA damage response to cisplatin by supporting p53 activation
Eukaryotic elongation factor 2 (eEF2) kinase (eEF2K) is a stress-responsive hub that inhibits the translation elongation factor eEF2, and...
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Avian Diversity: A Comprehensive Bird Checklist of Graphic Era (Deemed to be University), Dehradun (Western Himalaya), India
AbstractThe present study aims to provide a comprehensive bird checklist of Graphic Era (Deemed to be University), Dehradun, India. The study was...
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Effects of Bacillus thuringiensis var. israelensis Strains and Toxins on the Pine Processionary Moth Thaumetopoea wilkinsoni (Lepidoptera: Notodontidae)
AbstractThe pine processionary moth Thaumetopoea wilkinsoni (Tams, 1926) (Lepidoptera: Notodontidae) is one of the most harmful species that causes...