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Exploring freshwater stream bacterial communities as indicators of land use intensity
BackgroundStream ecosystems comprise complex interactions among biological communities and their physicochemical surroundings, contributing to their...
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Emerging role of glutathione peroxidase 4 in myeloid cell lineage development and acute myeloid leukemia
Phospholipid Hydroperoxide Gluthatione Peroxidase also called Glutathione Peroxidase 4 is one of the 25 described human selenoproteins. It plays an...
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Effects of altering the ratio of C16:0 and cis-9 C18:1 in rumen bypass fat on growth performance, lipid metabolism, intestinal barrier, cecal microbiota, and inflammation in fattening bulls
BackgroundC16:0 and cis -9 C18:1 may have different effects on animal growth and health due to unique metabolism in vivo. This study was investigated...
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Unveiling novel genetic variants in 370 challenging medically relevant genes using the long read sequencing data of 41 samples from 19 global populations
Background: A large number of challenging medically relevant genes (CMRGs) are situated in complex or highly repetitive regions of the human genome,...
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Broadcasters, receivers, functional groups of metabolites, and the link to heart failure by revealing metabolomic network connectivity
Background and ObjectiveBlood-based small molecule metabolites offer easy accessibility and hold significant potential for insights into health...
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TaqTth-hpRNA: a novel compact RNA-targeting tool for specific silencing of pathogenic mRNA
Pathogenic allele silencing is a promising treatment for genetic hereditary diseases. Here, we develop an RNA-cleaving tool, TaqTth-hpRNA, consisting...
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Transcriptomic responses of Mediterranean sponges upon encounter with symbiont microbial consortia
BackgroundSponges (phylum Porifera) constantly interact with microbes. They graze on microbes from the water column by filter-feeding and they harbor...
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Proteomic analysis of lung responses to SARS-CoV-2 infection in aged non-human primates: clinical and research relevance
With devastating health and socioeconomic impact worldwide, much work is left to understand the Coronavirus Disease 2019 (COVID-19), with emphasis in...
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Source and level of dietary iron influence semen quality by affecting inflammation, oxidative stress and iron utilization levels in boars
BackgroundBoars fed a mixed form of inorganic and organic iron in excess of the NRC recommended levels still develop anemia, which suggested that the...
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First trials exploring the potential of phytoseiid mites in managing lychee erinose mite, Aceria litchii (Keifer) (Acari: Eriophyidae), infestations on lychee plants
Phytoseiid mites have been frequently found in association with the lychee erinose mite, Aceria litchii , on lychee plants in Brazil, suggesting that...
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Heat stress affects mammary metabolism by influencing the plasma flow to the glands
BackgroundEnvironmental heat stress (HS) can have detrimental effects on milk production by compromising the mammary function. Mammary plasma flow...
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The Adaptive Role of Bark in the Diet of Budongo Chimpanzees (Pan troglodytes schweinfurthii)
The ingestion of bark has been observed across the animal kingdom and is well documented in free-ranging chimpanzees. Thus far, the best-supported...
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Genetic and genomic analysis of Belgian Blue’s susceptibility for psoroptic mange
BackgroundPsoroptic mange, caused by Psoroptes ovis mites, is affecting Belgian Blue cattle’s welfare and production potential. The Belgian Blue...
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Expanding the genetic and phenotypic spectrum of Baker–Gordon syndrome: a new de novo SYT1 variant
We report the case of a Spanish pediatric patient with developmental delay, hypotonia, feeding difficulties, visual problems, and hyperkinetic...
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Functional and evolutionary comparative analysis of the DIR gene family in Nicotiana tabacum L. and Solanum tuberosum L.
BackgroundThe dirigent ( DIR ) genes encode proteins that act as crucial regulators of plant lignin biosynthesis. In Solanaceae species, members of...
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Molecular and immunological studies on Theileria equi and its vector in Egypt
Equine piroplasmosis is not fully understood regarding pathogenicity, prophylaxis, host immune response expression, and specific vectors. Accurately...
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Unraveling the genomic secrets of Tritonibacter mobilis AK171: a plant growth-promoting bacterium isolated from Avicennia marina
The scarcity of freshwater resources resulting in a significant yield loss presents a pressing challenge in agriculture. To address this issue,...
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Population genetic structure of Culex tritaeniorhynchus in different types of climatic zones in China
BackgroundCulex tritaeniorhynchus is widely distributed in China, from Hainan Island in the south to Heilongjiang in the north, covering tropical,...
