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Next-generation neuropeptide Y receptor small-molecule agonists inhibit mosquito-biting behavior
BackgroundFemale Aedes aegypti mosquitoes can spread disease-causing pathogens when they bite humans to obtain blood nutrients required for egg...
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Diagnostic accuracy of an automated microscope solution (miLab™) in detecting malaria parasites in symptomatic patients at point-of-care in Sudan: a case–control study
BackgroundMicroscopic detection of malaria parasites is labour-intensive, time-consuming, and expertise-demanding. Moreover, the slide interpretation...
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Efficacy and safety of single-dose artesunate plus sulfalene/pyrimethamine combined with praziquantel for the treatment of children with Schistosoma mansoni or Schistosoma haematobium in western Kenya: a randomised, open-label controlled trial
BackgroundReliance on praziquantel for the treatment and control of schistosomiasis is likely to facilitate the emergence of drug resistance....
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Myocarditis associated with COVID-19 vaccination
Following the start of the COVID-19 vaccination campaign, the adverse events of myocarditis and pericarditis were linked mainly to mRNA COVID-19...
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Association between indoor residual spraying and the malaria burden in Zambia and factors associated with IRS refusals: a case-control study in Vubwi District
BackgroundIndoor residual spraying (IRS) has been implemented to prevent malaria in Zambia for several decades, but its effectiveness has not been...
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A geospatial analysis of local intermediate snail host distributions provides insight into schistosomiasis risk within under-sampled areas of southern Lake Malawi
BackgroundAlong the southern shoreline of Lake Malawi, the incidence of schistosomiasis is increasing with snails of the genera Bulinus and Biomphalaria...
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Evaluation of Parasight All-in-One system for the automated enumeration of helminth ova in canine and feline feces
BackgroundDigital imaging combined with deep-learning-based computational image analysis is a growing area in medical diagnostics, including...
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Centenarians, semi and supercentenarians, COVID-19 and Spanish flu: a serological assessment to gain insight into the resilience of older centenarians to COVID-19
BackgroundAlthough it is well known that the older people have been the most susceptible to COVID-19, there are conflicting data on the...
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Large-scale performance assessment of the BG-Counter 2 used with two different mosquito traps
BackgroundMosquitoes are important vectors of pathogens. They are usually collected with CO 2 -baited traps and subsequently identified by morphology....
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Total antioxidant status levels in malaria: a systematic review and meta-analysis
BackgroundMalaria, a severe health threat, significantly affects total antioxidant status (TAS) levels, leading to considerable oxidative stress....
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Investigation of antimicrobial susceptibility patterns, risk factors and their impact on mortality in cancer patients at a tertiary care cancer hospital- A prospective study
BackgroundCancer patients are vulnerable to infections due to immunosuppression caused by cancer itself and its treatment. The emergence of...
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Ecology and geography of Cache Valley virus assessed using ecological niche modeling
BackgroundCache Valley virus (CVV) is an understudied Orthobunyavirus with a high spillover transmission potential due to its wide geographical...
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Molecular-phylogenetic investigation of trichomonads in dogs and cats reveals a novel Tritrichomonas species
BackgroundTrichomonosis is a common infection in small animals, mostly manifesting in gastrointestinal symptoms such as diarrhea. Although oral...
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High prevalence and risk of malaria among asymptomatic individuals from villages with high prevalence of artemisinin partial resistance in Kyerwa district of Kagera region, north-western Tanzania
BackgroundAlthough Tanzania adopted and has been implementing effective interventions to control and eventually eliminate malaria, the disease is...
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Systemic prime mucosal boost significantly increases protective efficacy of bivalent RSV influenza viral vectored vaccine
Although licensed vaccines against influenza virus have been successful in reducing pathogen-mediated disease, they have been less effective at...
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A safe and potentiated multi-type HPV L2-E7 nanoparticle vaccine with combined prophylactic and therapeutic activity
Persistent infection with high-risk human papillomavirus (HPV) is widely recognized as the primary cause of cervical and other malignant cancers....
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Adoptive NK cell therapy: a potential revolutionary approach in longevity therapeutics
The aging process intricately involves immune system dynamics, with a crucial role in managing senescent cells (SNCs) and their senescence-associated...
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The direct effect of SARS-CoV-2 virus vaccination on human ovarian granulosa cells explains menstrual irregularities
Following administration of the SARS-CoV-2 vaccine, many women worldwide reported short-term menstrual irregularities. Although menstrual bleeding,...
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A gH/gL-encoding replicon vaccine elicits neutralizing antibodies that protect humanized mice against EBV challenge
Epstein-Barr virus (EBV) is associated with several malignancies, neurodegenerative disorders and is the causative agent of infectious mononucleosis....
