-
Article
Population pharmacokinetics and pharmacodynamics of ticagrelor and AR-C124910XX in Chinese healthy male subjects
Ticagrelor, the first reversible P2Y12 receptor antagonist, exhibits faster onset and offset of antiplatelet effects and more consistent platelet inhibition than clopidogrel in both healthy subjects and patients ...
-
Article
X-ray fluorescence microtomography based on polycapillary-focused X-rays from laboratory source
X-ray fluorescence microtomography (μXFCT) is a nondestructive analytical technique and has been widely used to nondestructively detect and quantify the elemental composition and distributions in samples. Usua...
-
Article
Effects of a volatile solvent with low surface tension combining with the silica network reinforcement on retention of LLC structure in polymer matrix
Organic polymers with ordered nanostructures templated from lyotropic liquid crystals (LLC) have many potential applications in areas such as membranes, tissue engineering, and drug delivery. However, after re...
-
Article
Open AccessTestes-specific protease 50 (TSP50) promotes invasion and metastasis by inducing EMT in gastric cancer
TSP50 (testes-specific protease 50) has been reported to be a candidate oncogene and is overexpressed in various cancers. Our previous study demonstrated that TSP50 protein is elevated in gastric cancer, and i...
-
Article
Constraints on the genesis of the Jiande polymetallic copper deposit in South China using fluid inclusion and O-H-Pb isotopes
The Jiande copper deposit is located in the Qin-Hang metallogenic belt, South China. The deposit is dominated by “stratiform-like” ores, which are hosted in the dolomite of the Upper Carboniferous Huanglong Fo...
-
Article
Open AccessSpatial-temporal distribution of dengue and climate characteristics for two clusters in Sri Lanka from 2012 to 2016
Dengue is a vector-borne disease causing high morbidity and mortality in tropical and subtropical countries. Urbanization, globalization, and lack of effective mosquito control have lead to dramatically increa...
-
Article
Sunitinib is effective and tolerable in Chinese patients with advanced pancreatic neuroendocrine tumors: a multicenter retrospective study in China
To determine the efficacy and safety of sunitinib in Chinese patients with unresectable or metastatic pancreatic neuroendocrine tumors (pNETs) and the clinical significance of steady-state sunitinib serum con...
-
Article
Acoustic Goos-Hänchen effect
We report two models of the lateral displacement of acoustic-wave scattering on a fluid-solid interface that reveal an acoustic analog of the Goos-Hänchen effect in optics. This acoustic analog is called the a...
-
Chapter and Conference Paper
Detecting Command and Control Channel of Botnets in Cloud
The rapid rise of cloud computing technology marks the next wave of enterprise information technology, catering up a market demand of a digitized economy to deliver traditional utilities such as electricity, g...
-
Chapter
An Enhanced CUSUM Algorithm for Anomaly Detection
Anomaly detection has been extensively studied in the last two decades. Features are usually selected or created at first for characterizing behaviours of networks, users or systems, and then anomaly detection...
-
Article
System sourcing and information processing capability in supply chains: a study of small suppliers
Although the adoption of inter-organizational systems (IOS) has been studied extensively in the existing literature, relatively little research attention has been paid to how small firms in supply chains are i...
-
Article
Acetylcholinesterase-independent protective effects of huperzine A against iron overload-induced oxidative damage and aberrant iron metabolism signaling in rat cortical neurons
Iron dyshomeostasis is one of the primary causes of neuronal death in Alzheimer's disease (AD). Huperzine A (HupA), a natural inhibitor of acetylcholinesterase (AChE), is a licensed anti-AD drug in China and a...
-
Chapter
A Multi-risk Model for Understanding the Spread of Chlamydia
Chlamydia trachomatis, CT, infection is the most frequently reported sexually transmitted infection in the United States. To better understand the recent increase in disease prevalence, and help guide in mitig...
-
Chapter
Modeling the Impact of Behavior Change on the Spread of Ebola
We create a compartmental mathematical model to analyze the role of behavior change in slowing the spread of the Ebola virus disease (EVD) in the 2014–2015 Western Africa epidemic. Our model incorporates behav...
-
Article
Optical fabrication of two-dimensional photorefractive periodic photonic lattices and quasicrystal microstructures by multi-lens board
We experimentally demonstrate a convenient approach to fabricate two-dimensional periodic photonic lattices and quasicrystal microstructures in iron-doped lithium niobate photorefractive crystal by multi-lens...
-
Article
[IrO4]+ at the IX (+9) oxidation state observed, report states
-
Article
Open AccessOverexpression of GOLPH3 is associated with poor prognosis and clinical progression in pancreatic ductal adenocarcinoma
Golgi phosphoprotein 3 (GOLPH3) has been identified as an oncoprotein in various human cancers; however, its role in pancreatic ductal adenocarcinoma (PDAC) is unknown. We examined GOLPH3 expression levels and...
-
Article
Classical-Operation-Based Deterministic Secure Quantum Communication
We generalize the unitary-operation-based deterministic secure quantum communication (UODSQC) model (protocol) to describe the conventional deterministic secure quantum communication (DSQC) protocols in which ...
-
Article
Open AccessSpecies identification through mitochondrial rRNA genetic analysis
Inter-species and intraspecific variations in mitochondrial DNA (mtDNA) were observed in a bioinformatics analysis of the mitochondrial genomic sequences of 11 animal species. Some highly conserved regions wer...
-
Article
Molecular alterations of EGFR in small intestinal adenocarcinoma
Molecular testing for epidermal growth factor receptor (EGFR) mutations has recently become a standard practice for the management of patients with non-squamous none small cell lung cancer. Primary small intestin...
