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Article
A \({-}30\,^{\circ }\hbox {C}\) to \(80\,^{\circ }\hbox {C}\) Stirred-Liquid-Bath-Based Blackbody Source
At the national facility for blackbody source radiance temperature calibration of the National Institute of Metrology, China, a stirred liquid bath blackbody was developed for use as a radiance temperature ref...
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Article
Open AccessCaspase-9 mediates Puma activation in UCN-01-induced apoptosis
The protein kinase inhibitor 7-hydroxystaurosporine (UCN-01) is one of the most potent and frequently used proapoptotic stimuli. The BH3-only molecule of Bcl-2 family proteins has been reported to contribute t...
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Article
Novel functional magnetic resonance imaging biomarkers for assessing response to therapy in hepatocellular carcinoma
The established and adapted image biomarkers based on size for tumor burden measurement continue to be applied to hepatocellular carcinoma (HCC) as size measurement can easily be used in clinical practice. How...
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Article
Open AccessαNAC inhibition of the FADD-JNK axis plays anti-apoptotic role in multiple cancer cells
Nascent polypeptide-associated complex α (αNAC) is reportedly overexpressed in several types of cancers and regulates cell apoptosis under hypoxic conditions in HeLa cells. The aim of our study was to investigate...
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Article
SIRT1 regulates YAP2-mediated cell proliferation and chemoresistance in hepatocellular carcinoma
The MST/YAP (mammalian Ste20-like kinase/Yes-associated protein 2) pathway plays an important role in hepatocellular carcinoma (HCC). Although post-translational modification—especially MST/Lats (large tumor s...
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Article
Dynamic CT of solitary pulmonary nodules: comparison of contrast medium distribution characteristic of malignant and benign lesions
To prospectively assess the role of the dynamic contrast-enhanced CT enhancement characteristics in distinguishing malignant form of benign solitary pulmonary nodules.
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Article
The tumor suppressor Caliban regulates DNA damage-induced apoptosis through p53-dependent and -independent activity
We previously identified Caliban (Clbn) as the Drosophila homolog of human Serologically defined colon cancer antigen 1 gene and demonstrated that it could function as a tumor suppressor in human non-small-cell l...
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Article
Open AccessBlockade of inhibitors of apoptosis (IAPs) in combination with tumor-targeted delivery of tumor necrosis factor-α leads to synergistic antitumor activity
In the current study, we examined whether the combination of tumor vasculature-targeted gene therapy with adeno-associated virus bacteriophage-tumor necrosis factor-α (AAVP-TNF-α) and/or the orally administere...
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Article
Cocaine-induced cortical microischemia in the rodent brain: clinical implications
Cocaine-induced stroke is among the most serious medical complications associated with its abuse. However, the extent to which acute cocaine may induce silent microischemia predisposing the cerebral tissue to ...
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Article
Enhanced antitumor effect of cisplatin in human NSCLC cells by tumor suppressor LKB1
LKB1 is a novel candidate tumor suppressor gene in lung cancer. In this study, we evaluated the effect of cationic liposomes (LPs)-mediated LKB1 gene (LPs-pVAX-LKB1) on low-dose cisplatin (cis-diamminedichloropla...
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Article
Study on Reducing the Size-of-Source Effect of Pyrometers
The size-of-source effect (SSE) is an important uncertainty source in radiation thermometry when radiation targets with different sizes are measured. In this article, a test pyrometer was established to study ...
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Article
Spectral Radiation Drift of LEDs Under Step-Mode Operation and Its Effect on the Measurement of the Non-Linearity of Radiation Thermometers
The non-linearity (NL) of radiation thermometers is critically involved when realizing ITS-90 above the silver point. It has to be corrected for, and its uncertainty should be adequately specified. In this art...
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Article
Molecular level dynamics of genetic oscillator—The effect of protein-protein interaction
Uncovering how interactions of a set of molecular components influence the system’s dynamic behavior is important for understanding intracellular processes and elucidating design principles, but unfortunately,...
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Article
Size-of-Source Effect Difference Between Direct and Indirect Methods of Radiation Thermometers
The size-of-source effect (SSE) of radiation thermometers is generally determined using direct and indirect methods. The present paper describes the difference in the SSE obtained using the two methods. Three ...
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Article
Realization of ITS-90 Above the Silver Point at the NIM
The high-temperature primary standard system was gradually improved at the National Institute of Metrology (NIM) in China after 2004. A new primary standard pyrometer (PSP) was developed, one with a size-of-so...
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Article
Palladium nano-clusters grown on prestructured HOPG substrates
The growth of Palladium nano-clusters prepared by atomic beam deposition on prestructured highly oriented pyrolytic graphite (HOPG) surfaces has been investigated by means of scanning tunnelling microscopy (ST...
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Article
T 90 Measurement of Co-C, Pt-C, and Re-C High-Temperature Fixed Points at the NIM
The blackbodies of high-temperature fixed points (HTFPs), namely, Co-C, Pt-C, and Re-C eutectic points, were gradually established at the National Institute of Metrology (NIM) of China after 2007, and their ch...
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Article
Results of Long-Term Stability Tests Performed for the Eutectics Co–C and Pt–C
The stability of the Co–C and Pt–C eutectic fixed points is investigated in this article. Six cells were employed for the testing. Two existing cells, a Co–C cell with a C/C sheet incorporated and a Pt–C cell ...
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Article
Liver-specific microRNA-122 target sequences incorporated in AAV vectors efficiently inhibits transgene expression in the liver
Vectors based on adeno-associated virus (AAV) are effective in gene delivery in vivo. Tissue-specific gene expression is often needed to minimize ectopic expression in unintended cells and undesirable consequence...
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Article
Calibration of the Irradiance Responsivity of a Filter Radiometer for T Measurement at NIM
At the National Institute of Metrology of China (NIM), silicon photodiode-based narrow-band interference filter radiometers (FRs) have been designed for the radiometric determination of the thermodynamic tempe...
