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  1. Article

    Open Access

    Genome-wide identification and expression analysis of the PP2C gene family in Apocynum venetum and Apocynum hendersonii

    Protein phosphatase class 2 C (PP2C) is the largest protein phosphatase family in plants. Members of the PP2C gene family are involved in a variety of physiological pathways in plants, including the abscisic acid...

    Jiayi Chen, Yue Wang, Yongmei Wu, **aoyu Huang, **aojun Qiu in BMC Plant Biology (2024)

  2. Article

    Open Access

    Prediction of frequency response of sub-frame bushing and study of high-order fractional derivative viscoelastic model

    This paper presents experimental and dynamic modeling research on the rubber bushings of the rear sub-frame. The Particle Swarm Optimization algorithm was utilized to optimize a Backpropagation (BP) neural net...

    Bao Chen, Lunyang Chen, Feng Zhou, Jiang Huang, Zehao Huang in Scientific Reports (2024)

  3. Article

    Open Access

    Cost-Effectiveness of Laparoscopic Sleeve Gastrectomy for Chinese Patients

    Laparoscopic sleeve gastrectomy (LSG) is the most popular bariatric surgery procedure in China. However, its cost-effectiveness in Chinese patients is currently unknown.

    Weihua Yu, Jionghuang Chen, Luqi Fan, Chenli Yan, Linghua Zhu in Obesity Surgery (2024)

  4. Article

    Open Access

    Intact NMR Approach Quickly Reveals Synchronized Microstructural Changes in Oil-in-Water Nanoemulsion Formulations

    A soft-core oil-in-water (o/w) nanoemulsion (NE) is composed of nanometer (nm) sized oil droplets, stabilized by a surfactant layer and dispersed in a continuous bulky water phase. Characterization of the o/w ...

    Deyun Wang, Jiayi Li, Kang Chen in The AAPS Journal (2024)

  5. Article

    Open Access

    The association between osteoporosis and frailty: a cross-sectional observational study and mendelian randomization analysis

    Osteoporosis and frailty are two common features in the elderly population. Despite many review articles mentioning the association between osteoporosis and frailty, there is a lack of original research direct...

    Zhiqiang Que, Yilong Lin, Dingqiang Chen in Journal of Orthopaedic Surgery and Research (2024)

  6. Article

    Open Access

    Methylprednisolone Modulates the Tfr/Tfh ratio in EAE-Induced Neuroinflammation through the PI3K/AKT/FoxO1 and PI3K/AKT/mTOR Signalling Pathways

    Methylprednisolone (MP) is a potent glucocorticoid that can effectively inhibit immune system inflammation and brain tissue damage in Multiple sclerosis (MS) patients. T follicular helper (Tfh) cells are a sub...

    Nan Wu, Yun Zhao, Minjun **ao, Hui Liu, Hongliang Chen, Bin Liu in Inflammation (2024)

  7. Article

    Open Access

    Death associated protein like 1 acts as a novel tumor suppressor in melanoma by increasing the stability of P21 protein

    Melanoma is a primary malignant tumor with high lethality, which occurs in the skin and eye tissues, while the molecular mechanisms of melanomagenesis remain largely unknown. Here, we show that death-associate...

    **aoyan Liu, **aojuan Hu, Meiyu **g, Li** Huang in Molecular and Cellular Biochemistry (2024)

  8. Article

    Open Access

    A systematic review and meta-analysis of canine enteric coronavirus prevalence in dogs of mainland China

    Canine enteric coronavirus (CECoV) is a prevalent infectious disease among dogs worldwide, yet its epidemiology in mainland China remains poorly understood. This systematic review and meta-analysis aimed to as...

    Chaoyang Chen, **aoxia Ji, Tingting Zhang, Lin Ge, Mengting Sun in Virology Journal (2024)

  9. Article

    Open Access

    Incidence of metabolic syndrome in patients with unilateral or bilateral staghorn renal stones and its impact on percutaneous nephrolithotomy outcomes

    To evaluate the incidence of metabolic syndrome (MetS) in patients with unilateral and bilateral staghorn calculi (SC) and evaluate the impact on the outcome of percutaneous nephrolithotomy (PCNL).

    Zhonghua Shen, Linguo **e, Di Luo, Haijie **e, Hongyang Chen, Chunyu Liu in BMC Urology (2024)

  10. Article

    Open Access

    Clinical application of targeted next-generation sequencing in severe pneumonia: a retrospective review

    The precise identification of the underlying causes of infectious diseases, such as severe pneumonia, is essential, and the development of next-generation sequencing (NGS) has enhanced the effectiveness of pat...

    Peng Zhang, Baoyi Liu, Shuang Zhang, Xuefei Chang, Lihe Zhang, Dejian Gu in Critical Care (2024)

  11. Article

    Open Access

    Relationship between childhood trauma and non-suicidal self-injury in high school students: the mediating role of the stress perception and the moderating role of teacher-student relationship

    This study delves into the correlation between childhood trauma and non-suicidal self-injury (NSSI) behaviors among high school students. Additionally, it examines the mediating role of stress perception and t...

    Yilin Liu, Yuan Fang, Yuanling Chen, Fuyi Qin, **nrui Li, Ruibin Feng in BMC Psychology (2024)

  12. Article

    Open Access

    Genome wide identification of novel DNA methylation driven prognostic markers in colorectal cancer

    Colorectal cancer (CRC) stands as a major contributor to cancer-related fatalities within China. There is an urgent need to identify accurate biomarkers for recurrence predicting in CRC. Reduced representation...

    Yuhua Ma, Yuanxin Li, Zhahong Wen, Yining Lai, Kulaixijiang Kamila in Scientific Reports (2024)

  13. Article

    Open Access

    Chinese version of the Tendency to Avoid Physical Activity and Sport (TAPAS) scale: testing unidimensionality, measurement invariance, concurrent validity, and known-group validity among Taiwanese youths

    Psychosocial factors affect individuals’ desire for physical activity. A newly developed instrument (Tendency to Avoid Physical Activity and Sport; TAPAS) has been designed to assess the avoidance of physical ...

    Yi-Ching Lin, Jung-Sheng Chen, Nadia Bevan, Kerry S. O’Brien in BMC Psychology (2024)

  14. Article

    Open Access

    Biomechanically based Fu’s subcutaneous needling treatment for senile knee osteoarthritis: protocol for a randomized controlled trial

    Fu’s subcutaneous needling (FSN) is a new type of acupuncture that uses subcutaneous tissue to oscillate from side to side to improve muscle pathology status and can be effective in treating Knee osteoarthriti...

    Hai Huang, Ruixuan Liu, Jieying Shao in Journal of Orthopaedic Surgery and Research (2024)

  15. Article

    Open Access

    Epidemiology, economic, and humanistic burden of hereditary angioedema: a systematic review

    This systematic study aims to assess the global epidemiologic, economic, and humanistic burden of illness associated with all types of hereditary angioedema.

    **n Guan, Yanan Sheng, Shuang Liu, Miao He in Orphanet Journal of Rare Diseases (2024)

  16. Article

    Open Access

    LVPocket: integrated 3D global-local information to protein binding pockets prediction with transfer learning of protein structure classification

    Previous deep learning methods for predicting protein binding pockets mainly employed 3D convolution, yet an abundance of convolution operations may lead the model to excessively prioritize local information, ...

    Ruifeng Zhou, **g Fan, Sishu Li, Wenjie Zeng, Yilun Chen in Journal of Cheminformatics (2024)

  17. Article

    Open Access

    Genome-wide analysis of MYB transcription factor family and AsMYB1R subfamily contribution to ROS homeostasis regulation in Avena sativa under PEG-induced drought stress

    The myeloblastosis (MYB) transcription factor (TF) family is one of the largest and most important TF families in plants, playing an important role in a life cycle and abiotic stress.

    Yang Chen, Aixue Li, ** Yun, Quan Chen, Dayu Pan, Rui Guo, Han Zhang in BMC Plant Biology (2024)

  18. Article

    Open Access

    Abiotic synthesis of graphitic carbons in the Eoarchean Saglek-Hebron metasedimentary rocks

    Graphite in metasedimentary rocks of the Eoarchean Saglek-Hebron Gneiss Complex (Canada) is depleted in 13C and has been interpreted as one of the oldest traces of life on Earth. The variation in crystallinity of...

    Zixiao Guo, Dominic Papineau, Jonathan O’Neil, Hanika Rizo in Nature Communications (2024)

  19. Article

    Open Access

    Accuracy of dental implant placement using different dynamic navigation and robotic systems: an in vitro study

    Computer-aided implant surgery has undergone continuous development in recent years. In this study, active and passive systems of dynamic navigation were divided into active dynamic navigation system group and...

    Zonghe Xu, Lin Zhou, Bin Han, Shuang Wu, Yanjun **ao, Sihui Zhang in npj Digital Medicine (2024)

  20. Article

    Open Access

    High-intensity Focused Ultrasound-A New Choice to Conduct Pulmonary Artery Denervation

    This research aimed to explore whether high-intensity focused ultrasound (HIFU) could conduct pulmonary artery denervation (PADN). HIFU was performed in pulmonary arteries of 6 normotensive rabbits at dose of ...

    Yonghui **e, Taoyue Yao, **aogang Zhu in Journal of Cardiovascular Translational Re… (2024)

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