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  1. Article

    Open Access

    P4HA2 promotes proliferation, invasion, and metastasis through regulation of the PI3K/AKT signaling pathway in oral squamous cell carcinoma

    Proline 4-hydroxylase 2 (P4HA2) is known for its hydroxylase activity, primarily involved in hydroxylating collagen precursors and promoting collagen cross-linking under physiological conditions. Although its ...

    Zengpeng Chi, Qimin Wang, **n Wang, Dagang Li, Lei Tong, Yu Shi in Scientific Reports (2024)

  2. Article

    Open Access

    Role of atmospheric rivers in sha** long term Arctic moisture variability

    Atmospheric rivers (ARs) reaching high-latitudes in summer contribute to the majority of climatological poleward water vapor transport into the Arctic. This transport has exhibited long term changes over the p...

    Zhibiao Wang, Qinghua Ding, Renguang Wu, Thomas J. Ballinger in Nature Communications (2024)

  3. Article

    Open Access

    Chromosome-level genome assembly of Guide Black-Fur sheep (Ovis aries)

    Guide Black-Fur sheep (GD) is a breed of Tibetan sheep (Ovis aries) that lives in the Qinghai–Tibetan plateau region at an altitude of over 4,000 m. However, a lack of genomic information has made it difficult to...

    Zengkui Lu, Chao Yuan, Xuejiao An, Zhixiang Chen, Tingting Guo in Scientific Data (2024)

  4. Article

    Open Access

    Giant nonlinear Hall and wireless rectification effects at room temperature in the elemental semiconductor tellurium

    The second-order nonlinear Hall effect (NLHE) in non-centrosymmetric materials has recently drawn intense interest, since its inherent rectification could enable various device applications such as energy harv...

    Bin Cheng, Yang Gao, Zhi Zheng, Shuhang Chen, Zheng Liu in Nature Communications (2024)

  5. Article

    Open Access

    A generalized interval-valued p,q Rung orthopair fuzzy Maclaurin symmetric mean and modified regret theory based sustainable supplier selection method

    A novel interval valued p,q Rung orthopair fuzzy (IVPQ-ROF) multiple attribute group decision making (MAGDM) method for sustainable supplier selection (SSS) is proposed in this paper. This study mainly contain...

    Shuang Chen, Jian Ren, KeTing Ye, FeiYan Li in Scientific Reports (2024)

  6. Article

    Open Access

    Catalytic [4+2]- and [4+4]-cycloaddition using furan-fused cyclobutanone as a privileged C4 synthon

    Cycloaddition reactions play a pivotal role in synthetic chemistry for the direct assembly of cyclic architectures. However, hurdles remain for extending the C4 synthon to construct diverse heterocycles via pr...

    Kemiao Hong, Mengting Liu, Lixin Qian, Ming Bao, Gang Chen in Nature Communications (2024)

  7. Article

    Open Access

    The impact of telomere length on the risk of idiopathic normal pressure hydrocephalus: a bidirectional Mendelian randomization study

    Idiopathic normal pressure hydrocephalus (iNPH) affects mainly aged populations. The gradual shortening of telomere length (TL) is one of the hallmarks of aging. Whereas the genetic contribution of TL to the i...

    Zhihao Wang, Mingrong Zuo, Wenhao Li, Siliang Chen, Yunbo Yuan in Scientific Reports (2024)

  8. Article

    Open Access

    Integration of molecular docking and molecular dynamics simulations with subtractive proteomics approach to identify the novel drug targets and their inhibitors in Streptococcus gallolyticus

    Streptococcus gallolyticus (Sg) is a non-motile, gram-positive bacterium that causes infective endocarditis (inflammation of the heart lining). Because Sg has gained resistance to existing antibiotics and there i...

    Peng Chao, Xueqin Zhang, Lei Zhang, Ai** Yang, Yong Wang in Scientific Reports (2024)

  9. Article

    Open Access

    Application of citric acid can enhance the accuracy for 13C-urea breath tests in the diagnosis of Helicobacter pylori infection in Chinese patients

    Previous published data have confirmed that the addition of a citric acid meal improves the accuracy of the 13C-urea breath test (13C-UBT). However, some studies have suggested that a citric acid test meal may no...

    Gang Chen, Wei** Zhang, Qiaoling Wu, Qin Yu, Yong** Cai in Scientific Reports (2024)

  10. Article

    Open Access

    An entropy based spatial–temporal cube with its application to assess stress of overburden due to mining

    Underground coal seam mining significantly alters the stress and energy distribution within the overlying rock, leading to eventual structural degradation. Therefore, it is imperative to quantitatively identif...

    Changde Yang, Yang Chen, Binbin Yang, Chunshui Huang in Scientific Reports (2024)

  11. Article

    Open Access

    Assessment of cerebrovascular alterations induced by inflammatory response and oxidative–nitrative stress after traumatic intracranial hypertension and a potential mitigation strategy

    The rapid perfusion of cerebral arteries leads to a significant increase in intracranial blood volume, exposing patients with traumatic brain injury to the risk of diffuse brain swelling or malignant brain her...

    Shangming Zhang, Yehuang Chen, Qizuan Chen, Hongjie Chen in Scientific Reports (2024)

  12. Article

    Open Access

    Evaluation of dose delivery based on deformed CT using a commercial software for lung cancer

    This study employed a commercial software velocity to perform deformable registration and dose calculation on deformed CT images, aiming to assess the accuracy of dose delivery during the radiotherapy for lung...

    Jihong Chen, Kaiqiang Chen, Min OuYang, Guohua Wang, Penggang Bai in Scientific Reports (2024)

  13. Article

    Open Access

    Morphological and proteomic study of waterlogging tolerance in cotton

    Floating seedling cultivation technique is a novel seedling method in cotton and it provides an ideal model to study cotton growing under waterlogging stress. Morphological character and proteomic profile of t...

    Hao Zhang, Zhangshu **e, **aoju Tu, Aiyu Liu, **xiang Chen in Scientific Reports (2024)

  14. Article

    Open Access

    Biomechanical analysis of trunk and lower limbs during stair activity in patients with scoliosis

    Staircases are a frequently encountered obstacle in daily life, requiring individuals to navigate ascending and descending movements that place additional demands on the trunk and lower limbs compared to walki...

    Yanyun Gou, **g Tao, Jia Huang, Huangwei Lei, **ang Chen in Scientific Reports (2024)

  15. Article

    Open Access

    Exploration on OCT biomarker candidate related to macular edema caused by diabetic retinopathy and retinal vein occlusion in SD-OCT images

    To improve the understanding of potential pathological mechanisms of macular edema (ME), we try to discover biomarker candidates related to ME caused by diabetic retinopathy (DR) and retinal vein occlusion (RV...

    Yuhui Tao, Lexin Ge, Na Su, Mingchao Li, Wen Fan, Lin Jiang in Scientific Reports (2024)

  16. Article

    Open Access

    Research on machine learning forecasting and early warning model for rainfall-induced landslides in Yunnan province

    Landslides are highly destructive geological disasters that pose a serious threat to the safety of people’s lives and property. In this study, historical records of landslides in Yunnan Province, along with ei...

    Jia Kang, Bingcheng Wan, Zhiqiu Gao, Shaohui Zhou, Huansang Chen in Scientific Reports (2024)

  17. Article

    Open Access

    A biomechanics and energetics dataset of neurotypical adults walking with and without kinematic constraints

    Numerous studies have explored the biomechanics and energetics of human walking, offering valuable insights into how we walk. However, prior studies focused on changing external factors (e.g., walking speed) a...

    Tomislav Baček, Mingrui Sun, Hengchang Liu, Zhongxiang Chen in Scientific Data (2024)

  18. Article

    Open Access

    Landform and lithospheric development contribute to the assembly of mountain floras in China

    Although it is well documented that mountains tend to exhibit high biodiversity, how geological processes affect the assemblage of montane floras is a matter of ongoing research. Here, we explore landform-spec...

    Wan-Yi Zhao, Zhong-Cheng Liu, Shi Shi, Jie-Lan Li, Ke-Wang Xu in Nature Communications (2024)

  19. Article

    Open Access

    Genome-wide identification of starch phosphorylase gene family in Rosa chinensis and expression in response to abiotic stress

    Chinese rose (Rosa chinensis) is an important ornamental plant, with economic, cultural, and symbolic significance. During the application of outdoor greening, adverse environments such as high temperature and dr...

    Xu Li, Yang Chen, Zaiqi Zhang, Qin He, Tingting Tian, Yangmiao Jiao in Scientific Reports (2024)

  20. Article

    Open Access

    Lower psoas mass indicates worse prognosis in percutaneous vertebroplasty-treated osteoporotic vertebral compression fracture

    The correlation between lower psoas mass and the prognosis of osteoporotic vertebral compression fractures (OVCF) is still unclear. This study aims to investigate the impact of lower psoas mass on the prognosi...

    Kai Sun, Jianjun Liu, Haoran Zhu, Jiajia Wang, Haiwu Wan, Bo Huang in Scientific Reports (2024)

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