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Article
Understanding acute kidney injury in sepsis
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Article
Therapeutic hypothermia after out-of-hospital cardiac arrest in Finnish intensive care units: the FINNRESUSCI study
We aimed to evaluate post-resuscitation care, implementation of therapeutic hypothermia (TH) and outcomes of intensive care unit (ICU)-treated out-of-hospital cardiac arrest (OHCA) patients in Finland.
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Article
Erratum to: Incidence, risk factors and 90-day mortality of patients with acute kidney injury in Finnish intensive care units: the FINNAKI study
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Article
Incidence, risk factors and 90-day mortality of patients with acute kidney injury in Finnish intensive care units: the FINNAKI study
We aimed to determine the incidence, risk factors and outcome of acute kidney injury (AKI) in Finnish ICUs.
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Article
SuPAR and PAI-1 in critically ill, mechanically ventilated patients
SuPAR (soluble urokinase plasminogen activator receptor) and PAI-1 (plasminogen activator inhibitor 1) are active in the coagulation-fibrinolysis pathway. Both have been suggested as biomarkers for disease sev...
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Article
Five-year cost-utility analysis of acute renal replacement therapy: a societal perspective
Assessment of the cost utility (CU) of acute renal replacement therapy (RRT) from a societal perspective during a 5-year follow-up.
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Article
Is proton pump inhibitor use a significant confounder for chromogranin A levels in sepsis? Reply to Haranath and Jakkinaboina
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Article
Prognostic value of chromogranin A in severe sepsis: data from the FINNSEPSIS study
To assess the prognostic information of chromogranin A (CgA), a marker associated with adrenergic tone and myocardial function, in patients with severe sepsis.
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Article
Acute kidney injury in patients with influenza A (H1N1) 2009
We aim to evaluate the incidence and outcome of acute kidney injury (AKI) among critically ill adult patients with H1N1 2009 infection.
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Article
Open AccessCirculating high sensitivity troponin T in severe sepsis and septic shock: distribution, associated factors, and relation to outcome
To assess the clinical utility of a recently developed highly sensitive cardiac troponin T (hs-cTnT) assay for providing prognostic information on patients with sepsis.
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Article
Open AccessComparison of two utility instruments, the EQ-5D and the 15D, in the critical care setting
Reliable measures are required for proper cost–utility analysis after critical care. No gold standard is available, but the EQ-5D health-related quality of life instrument (HRQoL) has been proposed. Our aim wa...
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Article
Are small hospitals with small intensive care units able to treat patients with severe sepsis?
To find out whether mortality from sepsis is influenced by the size of the hospital and of the intensive care unit (ICU).
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Article
Acute respiratory failure in intensive care units. FINNALI: a prospective cohort study
To evaluate the incidence, treatment and mortality of acute respiratory failure (ARF) in Finnish intensive care units (ICUs).
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Article
Case-mix-adjusted length of stay and mortality in 23 Finnish ICUs
To create a tool for benchmarking intensive care units (ICUs) with respect to case-mix adjusted length of stay (LOS) and to study the association between clinical and economic measures of ICU performance.
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Article
HMGB1 as a predictor of organ dysfunction and outcome in patients with severe sepsis
To study the predictive value of high mobility group box-1 protein (HMGB1) and hospital mortality in adult patients with severe sepsis.
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Article
Glucose control in postresuscitation patients: Author’s reply
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Article
Strict versus moderate glucose control after resuscitation from ventricular fibrillation
Elevated blood glucose is associated with poor outcome in patients resuscitated from out-of-hospital cardiac arrest (OHCA). Our aim was to determine whether strict glucose control with intensive insulin treatm...
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Article
Association of cell-free plasma DNA with hospital mortality and organ dysfunction in intensive care unit patients
To investigate the concentration of cell-free plasma DNA and its association with organ dysfunction and hospital mortality in intensive care unit patients.
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Article
Mixed venous oxygen saturation cannot be estimated by central venous oxygen saturation in septic shock: reply to Dr. Bourdeaux
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Article
Incidence, treatment, and outcome of severe sepsis in ICU-treated adults in Finland: the Finnsepsis study
To determine the incidence and outcome of severe sepsis in the adult Finnish population and to evaluate how treatment guidelines in severe sepsis are applied in clinical practice.