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Article
Hematological effects on peri-transplant use of linezolid in adults undergoing single-unit cord blood transplantation
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Article
Cord blood index predicts engraftment and early non-relapse mortality in adult patients with single-unit cord blood transplantation
How to select optimal cord blood (CB) remains an important clinical question. We developed and validated an index of CB engraftment, the cord blood index (CBI), which uses three weighted variables representing...
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Article
Prognostic value of measurable residual disease at allogeneic transplantation for adults with core binding factor acute myeloid leukemia in complete remission
Pretransplant measurable residual disease (MRD) has been shown to be associated with relapse incidence following allogeneic hematopoietic cell transplantation (HCT) for acute myeloid leukemia (AML). However, i...
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Article
Allogeneic hematopoietic stem cell transplantation for myelodysplastic syndrome in adolescent and young adult patients
Allogeneic hematopoietic stem cell transplantation (HSCT) is the only curable treatment option for adolescent and young adult (AYA) patients with myelodysplastic syndrome (MDS). The study aim was to evaluate e...
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Article
Single cord blood transplantation for acute myeloid leukemia patients aged 60 years or older: a retrospective study in Japan
The availability of alternative donor sources could allow elderly patients to receive allogeneic hematopoietic cell transplantation (HCT). We retrospectively evaluated the outcomes of single-unit cord blood tr...
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Article
Relapse of acute myeloid leukemia after allogeneic hematopoietic cell transplantation: clinical features and outcomes
Posttransplant relapse represents the greatest obstacle to the success of allogeneic hematopoietic cell transplantation (HCT) for patients with acute myeloid leukemia (AML). This study investigated clinical fe...
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Article
Predicting non-relapse mortality following allogeneic hematopoietic cell transplantation during first remission of acute myeloid leukemia
The aim of this study was to develop a comprehensive system for predicting non-relapse mortality after allogeneic hematopoietic cell transplantation (HCT) during first complete remission (CR) of acute myeloid ...
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Article
Clinical outcomes of persistent colonization with multidrug-resistant Gram-negative rods in adult patients undergoing single cord blood transplantation
Severe bacterial infections are a serious problem after cord blood transplantation (CBT). Colonization with multidrug-resistant Gram-negative rods (MRGNR) is associated with increased morbidity and mortality a...
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Article
Allogeneic hematopoietic cell transplantation for adults with acute myeloid leukemia conducted in Japan during the past quarter century
Acute myeloid leukemia (AML) represents the most common indication for allogeneic hematopoietic cell transplantation (HCT). This study aimed to address the implementation status of allogeneic HCT for adults wi...
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Article
Early fluid overload predicts higher non-relapse and overall mortality in adults after single-unit cord blood transplantation
Early fluid overload has been associated with poor transplant outcomes after allogeneic hematopoietic cell transplantation. However, its effects on the outcomes after cord blood transplantation (CBT) are uncle...
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Article
Efficacy and safety of micafungin in unrelated cord blood transplant recipients
Micafungin (MCFG) is an echinocandin antifungal drug used for prophylaxis and treatment of fungal infections after allogeneic hematopoietic cell transplantation (HCT). However, its efficacy and safety in patie...
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Article
Epstein–Barr virus–associated post-transplant lymphoproliferative disorder among long-term survivors of adults after single cord blood transplantation without antithymocyte globulin
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Article
Red blood cell transfusion burden by day 30 predicts mortality in adults after single-unit cord blood transplantation
Increased red blood cell (RBC) transfusion requirements are associated with morbidity and mortality after allogeneic hematopoietic cell transplantation. However, its impact on the outcomes after cord blood tra...
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Article
Unit selection for umbilical cord blood transplantation for adults with acute myeloid leukemia in complete remission: a Japanese experience
To investigate optimal unit selection for umbilical cord blood transplantation (UCBT), we conducted a registry-based study of 1355 adults with acute myeloid leukemia in first or second complete remission who u...
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Article
Risk factors and survival impact of readmission after single-unit cord blood transplantation for adults
Hospital readmissions have been used as a prognostic indicator for patients receiving allogeneic hematopoietic cell transplantation (HCT). However, the impact of readmission during early and mid-phase of cord ...
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Article
Circulating monocyte subsets in human chronic graft-versus-host disease
Chronic graft-versus-host disease (cGVHD) is a major cause of late morbidity and mortality after allogeneic hematopoietic cell transplantation (HCT). Monocytes/macrophages play a central role in inflammation, ...
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Article
Allogeneic hematopoietic cell transplantation in adult acute myeloid leukemia with 11q23 abnormality: a retrospective study of the Adult Acute Myeloid Leukemia Working Group of the Japan Society for Hematopoietic Cell Transplantation (JSHCT)
An 11q23 abnormality presents in approximately 5% of adults with acute myeloid leukemia (AML) and is associated with adverse outcomes even after allogeneic hematopoietic cell transplantation (allo-HCT). To eva...
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Article
Does marital status affect the outcomes after allogeneic hematopoietic cell transplantation?
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Article
A cross-sectional study on late taste disorders in survivors of allogeneic hematopoietic cell transplantation
Taste disorders are one of the most common complications in patients undergoing allogeneic hematopoietic cell transplantation (HCT). They persist in some patients as a late complication 3 months or more after ...
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Article
Cancer progression by reprogrammed BCAA metabolism in myeloid leukaemia
BCAT1, a cytosolic aminotransferase for branched-chain amino acids (BCAAs), is aberrantly activated and functionally required for disease progression in chronic myeloid leukaemia.
