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  1. Article

    Open Access

    Expression of telomerase-associated protein 1 and telomerase reverse transcriptase in hepatocellular carcinoma

    To know whether two protein components of human telomerase (human telomerase-associated protein 1 (hTEP1) and human telomerase reverse transcriptase (hTERT) are useful markers for telomerase activation in huma...

    N Toshikuni, K Nouso, T Higashi, H Nakatsukasa, T Onishi in British Journal of Cancer (2000)

  2. No Access

    Chapter and Conference Paper

    Effect of Varietal Field Resistance for Control of Rice Blast

    Rice blast caused by Pyricularia oryzae Cav. (telemoiph: Magnaporthe grisea (Hebert) Barr) is the most widely distributed and most serious disease in Japan. Blast resistance in rice plants is the most important g...

    M. Yamaguchii, H. Saitoh, T. Higashi in Advances in Rice Blast Research (2000)

  3. Article

    Open Access

    Expression of MAGE-1 and -3 genes and gene products in human hepatocellular carcinoma

    MAGE gene family encodes peptides recognized by autologous cytotoxic T lymphocytes in a major histocompatibility complex (MHC) class-I restricted fashion. In the present study, we have performed reverse-transc...

    K Kariyama, T Higashi, Y Kobayashi, K Nouso, H Nakatsukasa in British Journal of Cancer (1999)

  4. Article

    Open Access

    Expression of membrane cofactor protein (MCP, CD46) in human liver diseases

    Membrane cofactor protein (MCP, CD46) is one of the complement regulatory proteins, and is widely distributed in human organs and protects cells from complement-mediated cytotoxicity. We analysed the distribut...

    N Kinugasa, T Higashi, K Nouso, H Nakatsukasa, Y Kobayashi in British Journal of Cancer (1999)

  5. No Access

    Chapter and Conference Paper

    Effects of Ground Vibrations on Absolute Gravity Measurement in Kyoto

    In October 1995, absolute gravity measurement using the FG5 (#104) gravimeter was carried out at the Supplementary Fundamental Gravity Station (Kyoto C) in Kyoto University by the Geographical Survey Institute...

    S. Takemoto, T. Higashi, A. Mukai, H. Nose in Gravity, Geoid and Marine Geodesy (1997)

  6. No Access

    Article

    Alzheimer-type pathology in a patient with mitochondrial myopathy, encephalopathy, lactic acidosis and stroke-like episodes (MELAS)

    A 53-year-old Japanese woman with a point mutation in mitochondrial DNA (tRNALeu(UUR), nt3243) consistent with mitochondrial myopathy, encephalopathy, lactic acidosis and stroke-like episodes (MELAS) and Alzheim...

    M. Kaido, H. Fujimura, F. Soga, K. Toyooka, H. Yoshikawa in Acta Neuropathologica (1996)

  7. No Access

    Article

    Ultrastructural changes in the lung in Niemann-Pick type C mouse

    The biochemical and morphological aspects of BALB/c mice with many features of the Niemann-Pick disease type C in man (NP-C mouse) have been studied extensively. However, the pulmonary pathology has not been s...

    T. Manabe, T. Yamane, T. Higashi, P. G. Pentchev, K. Suzuki in Virchows Archiv (1995)

  8. No Access

    Article

    Change in fibrinolytic activity as a parameter for assessing local mechanical stimulation during physical exercise

    The influences of mechanical force during physical exercise on blood coagulation and fibrinolysis were investigated and the effects of sports equipment, especially shoes were also examined. As an experimental ...

    N. Takashima, T. Higashi in European Journal of Applied Physiology and… (1994)

  9. No Access

    Article

    Syrian hamster embryo cell lines useful for detecting transforming genes in mouse tumours: detection of transforming genes in X-ray-related mouse tumours

    The Syrian hamster embryo cell lines, SHOK and MC-1, were used as recipient cells for DNA transfection assay to detect transforming genes in experimental mouse tumours. A mouse repeat sequence was utilised to ...

    H Sasai, T Higashi, S Nakamori, J Miyoshi, F Suzuki, T Nomura in British Journal of Cancer (1993)

  10. No Access

    Article

    Strain analysis by mismatch moire method and grid method using Fourier transform

    We have formerly presented a new method of the moire analysis of strain using the Fourier transform. It uses the phase information of the moire fringe brightness. By shifting the Fourier spectrum of the image ...

    Y. Morimoto, Y. Seguchi, T. Higashi in Computational Mechanics (1990)

  11. No Access

    Article

    Two-dimensional moiré method and grid method using Fourier transform

    Formerly, the authors presented one-dimensional strain analysis by a moiré method using a Fourier transform. In the present work, the method is extended to two-dimensional strain analysis. The analysis is comp...

    Y. Morimoto, Y. Seguchi, T. Higashi in Experimental Mechanics (1989)

  12. No Access

    Chapter and Conference Paper

    Moire Analysis of Strain by Fourier Transform

    We present a new method of the moire analysis of strain using the Fourier transform. The analysis is completely automatized by introducing the digital image processing. All of the laborious and subjective proc...

    Y. Morimoto, Y. Seguchi, T. Higashi in Computational Mechanics ’88 (1988)

  13. No Access

    Article

    Effective Debye-Waller parameter of carbons

    The effective Debye-Waller parameters,B eff, were determined along thec- anda-axes on two kinds of coke and a thermal black with different heat-treatment temperatures. FromB eff values at room temperature and aro...

    M. Inagaki, T. Higashi, Y. Sasaki, M. Toyoda, M. Sakai in Journal of Materials Science (1986)

  14. No Access

    Article

    Hyperammonemia-induced cytotoxic brain edema under osmotic opening of blood-brain barrier in dogs

    Infusion of an ammonium acetate solution into dogs during mannitol-induced reversible opening of the blood-brain barrier (BBB) resulted in a marked rise in intracranial pressure with exclusion of Evans blue dy...

    M. Fujiwara, A. Watanabe, T. Shiota, Y. Yamauchi in Research in Experimental Medicine (1985)

  15. No Access

    Article

    Effects of high hepatic acetaldehyde level following simultaneous administration of ethanol and cyanamide on liver function in rats

    Extremely high concentrations of hepatic acetaldehyde were induced in rats by the intragastric administration of ethanol and cyanamide, an aldehyde dehydrogenase inhibitor; and these high levels were maintaine...

    H. Nakatsukasa, A. Watanabe, M. Kobayashi, N. Hobara in Research in Experimental Medicine (1985)

  16. No Access

    Article

    Alterations in neutral amino acid transport across the blood-brain barrier in hepatic failure

    The accelerated transport of the blood neutral amino acids into the brain in encephalopathic patients with fulminant hepatitis and advanced liver cirrhosis was demonstrated not only by determining the cerebros...

    A. Watanabe, T. Higashi, T. Shiota, N. Takei in Research in Experimental Medicine (1983)

  17. No Access

    Chapter and Conference Paper

    Physiological Significance of Elevation of Liver γ-Glutamyltranspeptidase in Late Pregnancy

    γ-Glutamyltransferase (EC 2.3.2.2) activity in mouse fetal liver increases in late pregnancy to maximum (300- to 500-fold that of adult liver) at birth and then decreases to nearly the level in adult liver wit...

    T. Higashi, N. Tateishi in Functions of Glutathione in Liver and Kidney (1978)

  18. No Access

    Chapter and Conference Paper

    Turnover of Glutathione in Rat Liver

    The glutathione content of rat liver is usually 7 to 8 μmol/g. After starving rats for one day, glutathione decreases to between two-thirds and half the normal level. When starved rats are fed a diet containin...

    N. Tateishi, T. Higashi in Functions of Glutathione in Liver and Kidney (1978)

  19. No Access

    Article

    Peculiarity in gastric juice of gastric cancer

    K. Yunoki, T. Ichiki, H. Sato, T. Higashi, K. Misaka in Gastroenterologia Japonica (1969)

  20. No Access

    Article

    Relationship between gastric secretion and mucosal changes of the stomach with early cancer

    H. Sato, K. Yunoki, Y. Chuman, T. Higashi, T. Taneda in Gastroenterologia Japonica (1968)

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