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168 Result(s)
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Article
Tribute to Professor Kenji Mori and his contribution to Chemical Ecology
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Article
Open AccessCinnamomeoventrolide – Double Bond Regioisomerism in Frog Semiochemicals
Frogs of the families Mantellinae and Hyperoliidae possess male specific femoral or gular glands that are used during courtship. These glands release volatile compounds, e. g. the macrocyclic lactone gephyroma...
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Article
Open AccessAttenuated G protein signaling and minimal receptor phosphorylation as a biochemical signature of low side-effect opioid analgesics
Multi-receptor targeting has been proposed as a promising strategy for the development of opioid analgesics with fewer side effects. Cebranopadol and AT-121 are prototypical bifunctional ligands targeting the ...
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Article
Special Issues in Honor of Professor Dr. Dr. hc mult. Wittko Francke, 28 November 1940–27 December 2020
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Article
Open AccessIdentification of Cuticular and Web Lipids of the Spider Argiope bruennichi
Emerging evidence shows that the cuticular and silk lipids of spiders are structurally more diverse than those of insects, although only a relatively low number of species have been investigated so far. As in ...
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Article
KI in der Tumorpathologie
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Article
Special Issues in Honor of Professor Dr. Dr. hc mult. Wittko Francke, 28 November 1940 - 27 December 2020
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Article
Open AccessHA-MOP knockin mice express the canonical µ-opioid receptor but lack detectable splice variants
G protein-coupled receptors (GPCRs) are notoriously difficult to detect in native tissues. In an effort to resolve this problem, we have developed a novel mouse model by fusing the hemagglutinin (HA)-epitope t...
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Article
Open AccessPheromone communication among sexes of the garden cross spider Araneus diadematus
Chemical communication plays a fundamental role in many aspects of an animal’s life from assessing habitat quality to finding mating partners. Behavioural observations show that chemical communication likewise...
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Article
Microbial volatile organic compounds in intra-kingdom and inter-kingdom interactions
Microorganisms produce and excrete a versatile array of metabolites with different physico-chemical properties and biological activities. However, the ability of microorganisms to release volatile compounds ha...
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Article
Open AccessCollecting specialty-related medical terms: Development and evaluation of a resource for Spanish
Controlled vocabularies are fundamental resources for information extraction from clinical texts using natural language processing (NLP). Standard language resources available in the healthcare domain such as ...
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Article
Open AccessChemical Variation among Castes, Female Life Stages and Populations of the Facultative Eusocial Sweat Bee Halictus rubicundus (Hymenoptera: Halictidae)
In eusocial insects, chemical communication is crucial for mediating many aspects of social activities, especially the regulation of reproduction. Though queen signals are known to decrease ovarian activation ...
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Article
Open AccessNew phosphosite-specific antibodies to unravel the role of GRK phosphorylation in dopamine D2 receptor regulation and signaling
The dopamine D2 receptor (D2R) is the target of drugs used to treat the symptoms of Parkinson’s disease and schizophrenia. The D2R is regulated through its interaction with and phosphorylation by G protein recept...
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Article
Correction to: Technology Acceptance of a Machine Learning Algorithm Predicting Delirium in a Clinical Setting: a Mixed-Methods Study
A Correction to this paper has been published: https://doi.org/10.1007/s10916-021-01728-5
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Article
Open AccessTechnology Acceptance of a Machine Learning Algorithm Predicting Delirium in a Clinical Setting: a Mixed-Methods Study
Early identification of patients with life-threatening risks such as delirium is crucial in order to initiate preventive actions as quickly as possible. Despite intense research on machine learning for the pre...
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Article
Merkmalsextraktion aus klinischen Routinedaten mittels Text-Mining
Anti-VEGF-Medikamente prägen heute die Therapie von Makulaerkrankungen. In diesem Zusammenhang wird eine Fülle zusätzlicher Daten erhoben. Damit ließen sich Behandlungsverläufe besser verstehen und vorhersagen...
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Reference Work Entry In depth
Somatostatin
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Living Reference Work Entry In depth
Somatostatin
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Reference Work Entry In depth
Opioid Systems
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Chapter
Marketing und Sales Excellence – Handlungsempfehlungen zur Bewältigung dieses Dauerbrenners
In diesem Beitrag wird dargestellt, wie eine enge Partnerschaft zwischen Marketing und Vertrieb zu einem gelungenen und sich immer wieder neu anpassenden „Customer Journey Management“ führen wird. Es werden fo...