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Article
Upregulation of cytochrome c oxidase subunit 6b1 (Cox6b1) and formation of mitochondrial supercomplexes: implication of Cox6b1 in the effect of calorie restriction
Calorie restriction (CR), a non-genetic intervention that promotes longevity in animals, may exert anti-aging effects by modulating mitochondrial function. Based on our prior mitochondrial proteome analysis, w...
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Chapter
Internet Addiction and PET
Pathological use of the Internet is a new and rapidly growing worldwide phenomenon; however, few studies have examined the neurobiological factors underlying this condition. Internet addiction has been conside...
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Article
Tc-99m Hydroxymethylene Diphosphonate (HMDP) Renal Uptake as a Surrogate Marker of Postoperative Impairment of the Glomerular Filtration Rate in Renal Tumor Patients Following Nephron-Sparing Surgery
Purpose: We investigated Tc-99m hydroxymethylene diphosphonate (HMDP) scintigraphy findings in renal tumor patients from the perspective of postoperative renal dysfunction following nephron-sparing surgery (NS...
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Article
Routine Production of [18F]Flumazenil from Iodonium Tosylate Using a Sample Pretreatment Method: a 2.5-Year Production Report
[18F]Flumazenil, which has the advantage of a longer half-life than [11C]flumazenil, is well known for determining of the central benzodiazepine receptor concentrations. However, [18F]flumazenil has not been wide...
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Article
Evaluation of Flap Tissue Viability by F-18 FDG PET/CT
A 60-year-old man underwent vertical rectus abdominis myocutaneous flap to reconstruct a left lateral chest wall defect. For assessment of viability of muscle flap, F-18 fluoro-2-deoxyglucose (FDG) positron em...
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Article
A Case of Habitual Neck Compression Induced Electroencephalogram Abnormalities: Differentiating from Epileptic Seizures Using a Tc-99m HMPAO SPECT
Self-induced hypoxia has been reported particularly in adolescents, and it can result in neurological injury. Here, we present a case of electroencephalogram (EEG) abnormalities induced by habitual neck compre...
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Article
Open AccessA key role for neuropeptide Y in lifespan extension and cancer suppression via dietary restriction
Knowledge of genes essential for the life-extending effect of dietary restriction (DR) in mammals is incomplete. In this study, we found that neuropeptide Y (Npy), which mediates physiological adaptations to e...
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Article
Open AccessImproved measurement of the glomerular filtration rate from Tc-99m DTPA scintigraphy in patients following nephrectomy
We aimed to improve Tc-99m DTPA glomerular filtration rate (GFR) scintigraphy (Gates’ method) in a prospective study using Cr-51 EDTA GFR test as a gold standard.
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Article
Long-term clinical course with voltage-gated potassium channel antibody in Morvan’s syndrome
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Article
99mTc-Labeled RBC Scan in a Patient with Blue Rubber Bleb Nevus Syndrome: A Case Report
Blue rubber bleb nevus syndrome (BRBNS) is a rare disorder characterized by cutaneous and gastrointestinal vascular malformations. We report here the case of a 13-year-old patient with BRBNS who was suffering ...
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Article
Usefulness of Combined Metabolic–Volumetric Indices of 18F-FDG PET/CT for the Early Prediction of Neoadjuvant Chemotherapy Outcomes in Breast Cancer
The purpose of this study was to investigate the usefulness of metabolic-volumetric indices of 18F- fluorodeoxy-D-glucose (18F-FDG) positron emission tomography/computed tomography (PET/CT) for the evaluation of ...
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Article
Exploration of Optimal Dosing Regimens of Haloperidol, a D2 Antagonist, via Modeling and Simulation Analysis in a D2 Receptor Occupancy Study
To evaluate the potential usage of D2 receptor occupancy (D2RO) measured by positron emission tomography (PET) in antipsychotic development.
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Article
A simple and rapid detection of viral protein using RNA oligonucleotide in a biosensor
The monitoring of non-structural viral protein 3 (NS3) has been of considerable interest in develo** simple and reliable methods for detection of hepatitis C virus (HCV) for applications in diagnostic medicine....
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Article
Bronchial anthracofibrosis: a potential false-positive finding on F-18 FDG PET
Bronchial anthracofibrosis characterized by bronchostenosis associated with anthracotic pigmentation in bronchoscopic finding without a relevant history of pneumoconiosis or smoking has been recently described...
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Article
Repetitive Transcranial Magnetic Stimulation of the Left Dorsolateral Prefrontal Cortex Improves Probabilistic Category Learning
Traditionally, it has been thought that probabilistic category learning, one of the implicit memory functions, is dependent on the basal ganglia. However, there is growing evidence indicating the involvement o...
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Article
Metabolic Changes of Cerebrum by Repetitive Transcranial Magnetic Stimulation over Lateral Cerebellum: A Study with FDG PET
To better understand the functional role of cerebellum within the large-scale cerebellocerebral neural network, we investigated the changes of neuronal activity elicited by cerebellar repetitive transcranial m...
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Article
Evaluation of Salivary Gland Dysfunction Using Salivary Gland Scintigraphy in Sjögren’s Syndrome Patients and in Thyroid Cancer Patients after Radioactive Iodine Therapy
Salivary gland scintigraphy (SGS) provides an objective means of diagnosing salivary gland dysfunction in Sjögren’s syndrome (SS) patients and in thyroid cancer patients after radioactive iodine (RAI) therapy....
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Article
Extranigral extension of structural midbrain lesions overshadows parkinsonism
We report on a clinicoanatomical analysis of five patients with structural midbrain lesions who shared severe nigrostriatal dopaminergic denervation but presented different involuntary movements. The main clin...
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Article
Detection of Thyroid Metastasis of Renal Transitional Cell Carcinoma Using FDG PET/CT
A 69-year-old man who was diagnosed with renal transitional cell carcinoma (TCC) underwent F-18 fluorodeoxyglucose (FDG) positron emission tomography with computed tomography (PET/CT) for detecting recurrence ...
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Article
FDG-PET/CT Is Superior to Enhanced CT in Detecting Recurrent Subcentimeter Lesions in the Abdominopelvic Cavity in Colorectal Cancer
This study aims to compare the performance of contrast-enhanced computed tomography (CeCT) and 18 F-fluorodeoxyglucose positron emission tomography/computed tomography (FDG PET/CT) in detecting small tumor imp...
