3,713 Result(s)
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Ren-**ong Chen
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Article
Open AccessIntegrated machine learning algorithms reveal a bone metastasis-related signature of circulating tumor cells in prostate cancer
Bone metastasis is an essential factor affecting the prognosis of prostate cancer (PCa), and circulating tumor cells (CTCs) are closely related to distant tumor metastasis. Here, the protein-protein interactio...
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Open AccessCorrection: Melatonin synergizes BRAF-targeting agent vemurafenib in melanoma treatment by inhibiting iNOS/hTERT signaling and cancer-stem cell traits
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Open AccessUnderstanding and alleviating informal caregiver burden through the development and validation of a caregiver strain index-based model in Taiwan
Quantifying the informal caregiver burden is important for understanding the risk factors associated with caregiver overload and for evaluating the effectiveness of services provided in Long-term Care (LTC).
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Metabolic obesity phenotypes and all-cause mortality among the Chinese oldest-old population: a prospective cohort study
The obesity paradox has been reported among older adults. However, whether the favorable effect of obesity is dependent on metabolic status remains largely unknown. We aimed to explore the association of metab...
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Simplified p-i-n Perovskite Solar Cells with a Multifunctional Polyfullerene Electron Transporter
In prevailing p-i-n perovskite solar cells (PSCs), solution-processible fullerene molecules are widely used as electron-transporting layers (ETLs) but they typically suffer from poor uniformity and undesirable...
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Open AccessLeveraging Diverse Regulated Cell Death Patterns to Identify Diagnosis Biomarkers for Alzheimer’s Disease
The functions of regulated cell death (RCD) are closely related to Alzheimer’s disease (AD). However, very few studies have systematically investigated the diagnosis and immunologic role of RCD-related genes i...
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Lethal pulmonary thromboembolism in mice induced by intravenous human umbilical cord mesenchymal stem cell-derived large extracellular vesicles in a dose- and tissue factor-dependent manner
Mesenchymal stem cell-derived extracellular vesicles (MSC-EVs) have obvious advantages over MSC therapy. But the strong procoagulant properties of MSC-EVs pose a potential risk of thromboembolism, an issue tha...
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Open AccessCytoplasmic TP53INP2 acts as an apoptosis partner in TRAIL treatment: the synergistic effect of TRAIL with venetoclax in TP53INP2-positive acute myeloid leukemia
Acute myeloid leukemia (AML) is a hematopoietic malignancy with poor outcomes, especially in older AML patients. Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) is considered a promising antica...
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Multidisciplinary and multiscale nanoscience research roadmap based on large scientific facilities
With the advancement of modern science and technology, large scientific facilities are increasingly oriented toward demand and application, and can be used for basic research as well as serving multiple discip...
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Open AccessElectrical impedance tomography provides information of brain injury during total aortic arch replacement through its correlation with relative difference of neurological biomarkers
Postoperative neurological dysfunction (PND) is one of the most common complications after a total aortic arch replacement (TAAR). Electrical impedance tomography (EIT) monitoring of cerebral hypoxia injury du...
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Open AccessSensory ASIC3 channel exacerbates psoriatic inflammation via a neurogenic pathway in female mice
Psoriasis is an immune-mediated skin disease associated with neurogenic inflammation, but the underlying molecular mechanism remains unclear. We demonstrate here that acid-sensing ion channel 3 (ASIC3) exacerb...
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Influence of pier height on the safety of trains running on high-speed railway bridges during earthquakes
Sudden earthquakes pose a threat to the running safety of trains on high-speed railway bridges, and the stiffness of piers is one of the factors affecting the dynamic response of train-track-bridge system. In ...
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In situ reprogramming of cardiac fibroblasts into cardiomyocytes in mouse heart with chemicals
Cardiomyocytes are terminal differentiated cells and have limited ability to proliferate or regenerate. Condition like myocardial infarction causes massive death of cardiomyocytes and is the leading cause of d...
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Open AccessAmplitude analysis of the \( {\Lambda}_{\textrm{b}}^0\to {\textrm{pK}}^{-}\upgamma \) decay
The resonant structure of the radiative decay Λ b 0 ...
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Inconsistent Monthly Runoff Prediction Models Using Mutation Tests and Machine Learning
In a changing environment, the increasing inconsistency of runoff series complicates the development of runoff forecasting models. Mutation tests have frequently been employed to assess runoff inconsistency, y...
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Open AccessIntegrative single-cell and bulk transcriptomes analyses reveals heterogeneity of serine-glycine-one-carbon metabolism with distinct prognoses and therapeutic vulnerabilities in HNSCC
Metabolic heterogeneity plays a central role in sustaining uncontrolled cancer cell proliferation and sha** the tumor microenvironment (TME), which significantly compromises the clinical outcomes and respons...
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Open AccessLandform and lithospheric development contribute to the assembly of mountain floras in China
Although it is well documented that mountains tend to exhibit high biodiversity, how geological processes affect the assemblage of montane floras is a matter of ongoing research. Here, we explore landform-spec...
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Open AccessUniaxial extending neural probes for bleeding-absent implantation
Implantable neural probes, essential for brain electrophysiological research, have advanced with ultra-flexible designs to mitigate immune responses and postoperative complications. Strategies of shuttle-assis...
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Open AccessSingle-cell and spatially resolved interactomics of tooth-associated keratinocytes in periodontitis
Periodontitis affects billions of people worldwide. To address relationships of periodontal niche cell types and microbes in periodontitis, we generated an integrated single-cell RNA sequencing (scRNAseq) atla...
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Open AccessMicrobial imbalance in Chinese children with diarrhea or constipation
Diarrhea and constipation are common health concerns in children. Numerous studies have identified strong association between gut microbiota and digestive-related diseases. But little is known about the gut mi...
