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    Constitutive systemic expression of IL-1Ra or soluble TNF receptor by genetically modified hematopoietic cells suppresses LPS induction of IL-6 and IL-10

    We have been develo** both local and systemic gene therapy approaches to treat inflammatory and autoimmune diseases. To determine if systemic, constitutive expression of biologically active anti-inflammatory...

    LA Doughty, KD Patrene, CH Evans, SS Boggs, PD Robbins in Gene Therapy (1997)

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