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Article
Immunoblot analysis of the placental form of glutathione S-transferase in protein extracted from paraffin-embedded human glioma tissue
Protein extracted from conventional formalin-fixed and paraffin-embedded tissue sections of human gliomas was examined for immunoblot analysis using antibody against the placental form of glutathioneS-transferase...
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Article
Histochemistry with Helix pomatia agglutinin in human germ cell tumors: detection of nongerminomatous components and correlation between HPA reactivity and radiosensitivity in germinomas
Binding sites of Helix pomatia agglutinin (HPA) were examined in 32 patients with intracranial human germ cell tumors. HPA reactivity was found in vascular endothelial cells and erythrocytes of patients with bloo...
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Article
Expression of the placental form of glutathione S-transferase in pediatric gliomas
Expression of the human placental form of glutathione S-transferase (GST-θ) in pediatric gliomas, consisting of three pilocytic astrocytomas (grade 1), two fibrillary astrocytomas (grade 2), three anaplastic a...
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Article
Sensitization of C6 glioma cells to radiation by staurosporine, a potent protein kinase C inhibitor
The effect of staurosporine, a potent protein kinase C (PKC) inhibitor, on the sensitivity to radiation has been investigated in C6 glioma cells. Pretreatment of C6 cells with staurosporine at the concentratio...
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Article
Proliferative assessment of craniopharyngioma and epidermoid by nucleolar organizer region staining
The histologic distinction between craniopharyngioma and epidermoid is equivocal. Eight craniopharyngiomas and ten epidermoids (including three dermoids) as well as nine rat (Wistar) abdominal skins that acted...
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Article
Distribution of cellular carbohydrate moieties in human dysontogenetic brain tumors, especially in craniopharyngioma and epidermoid/dermoid
Cellular carbohydrate moieties of 65 human dysontogenetic brain tumors (craniopharyngioma, epidermoid/dermoid, Rathke cleft cyst, germinoma and non-germinomatous germ-cell tumors) and 60 common brain tumors (g...
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Article
Intracranial cavernous angioma in the 1st year of life and a review of the literature
Three cases of symptomatic cavernous angioma occurring in the 1st year of life are presented. All three patients were treated with radical extirpation. Postoperatively, two of them improved, but the third died...
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Article
Rapid detection of proliferating potential in human brain tumors by nucleolar organizer region staining on squash preparations
Rapid detection of the proliferating potential of 37 human brain tumors was attempted using squash preparations stained by a silver colloid technique for argyrophilic protein associated with nucleolar organize...
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Article
Assessment of proliferative potential in gliomatosis cerebri
The proliferative potential of neoplastic cells in two cases of gliomatosis cerebri was investigated by a combined staining technique, a one-step silver colloid method for nucleolar organizer region-associated...
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Chapter
Glutathione S-Transferase Placental Form in Human and Rat Gliomas and Its Possible Role in Drug Resistance
Glutathione S-transferases (GSTs) are an important family of the detoxifying enzymes catalyzing the conjugation of glutathione to a wide variety of hydrophobic electrophilic substances [1]. GSTs have various i...
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Chapter
Rapid Assessment of Malignancy in Human Brain Tumors on Squash Preparations Using Nucleolar Organizer Region Staining
The intraoperative histologic diagnosis on conventional rapid frozen sections is very helpful in deciding the area to be resected during the operation of a brain tumor. However, the inadequately conserved cons...
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Article
Surgical indications for infantile subdural effusion
Thirty-four cases of infantile subdural effusion (ISE) were reviewed in relation to surgical treatment and its prognosis during an average of 4 years of extended follow-up. The surgical indications were determ...
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Chapter
Clinical Analysis with 51 Cases of Meningocele and Meningomyelocele, with Special Reference to Hydrocephalus
Fifty-one cases with meningocele (MC), meningomyelocele (MMC), and encephalocele (EC) were analysed in association with the occurrence of hydrocephalus. The incidence of hydrocephalus for all cases was 56.9% o...
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Chapter
Surgical Treatment for Infantile Subdural Fluid Collections
Sixteen cases with infantile subdural fluid collections (SFC), which had no history of antecedent head injury, birth trauma, or intracranial infection, with onset symptoms of macrocrania (8 cases) and general ...
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Chapter and Conference Paper
Clinical and Experimental Studies of Leukotrienes in Subarachnoid Hemorrhage
Based on the free radical theory in biological systems, which was proposed in 1973 [3], actions of lipid peroxides relating to the mechanism of cerebral vasospasm after subarachnoid hemorrhage (SAH) have been ...
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Article
Postnatal development and enlargement of primary middle cranial fossa arachnoid cyst recognized on repeat CT scans
The etiology and mechanism of expansion of primary intracranial arachnoid cysts have been much debated. A rare case of an 8-month-old boy is reported, in which postnatal development and enlargement of a middle...
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Article
Sclerotic changes around the endolymphatic sac in human temporal bones
We used light microscopy to study 87 human temporal bones (from 47 cases) with no known otological disorders, and found that certain cases had sclerotic changes around the endolymphatic duct and sac. Changes i...