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  1. Article

    Open Access

    Core clock gene BMAL1 and RNA-binding protein MEX3A collaboratively regulate Lgr5 expression in intestinal crypt cells

    The intestinal epithelium is highly regenerative. Rapidly proliferating LGR5+ crypt base columnar (CBC) cells are responsible for epithelial turnover needed to maintain intestinal homeostasis. Upon tissue damage,...

    Li-Tzu Cheng, Grace Y. T. Tan, Fang-Pei Chang, Cheng-Kai Wang in Scientific Reports (2023)

  2. Article

    Open Access

    The relationship of exercise and cancer-related fatigue in patients with advanced liver cancer: a cross-sectional study

    There is increasing interest in understanding exercise as a potential treatment for cancer-related fatigue (CRF); however, rarely research has been conducted on more aggressive cancers with short survival, suc...

    Juan Li, Qinqin Cheng, **angqian Zhu, Sha Lin, Huan **ang, Wen Lu in Scientific Reports (2023)

  3. Article

    Open Access

    Neuropathologist-level integrated classification of adult-type diffuse gliomas using deep learning from whole-slide pathological images

    Current diagnosis of glioma types requires combining both histological features and molecular characteristics, which is an expensive and time-consuming procedure. Determining the tumor types directly from whol...

    Weiwei Wang, Yuanshen Zhao, Lianghong Teng, **g Yan, Yang Guo in Nature Communications (2023)

  4. Article

    Open Access

    Visible light-triggered selective C(sp2)-H/C(sp3)-H coupling of benzenes with aliphatic hydrocarbons

    The direct and selective coupling of benzenes with aliphatic hydrocarbons is a promising strategy for C(sp2)-C(sp3) bond formation using readily available starting materials, yet it remains a significant challeng...

    Qian-Yu Li, Shiyan Cheng, Ziqi Ye, Tao Huang, Fuxing Yang in Nature Communications (2023)

  5. Article

    Open Access

    Electronic Janus lattice and kagome-like bands in coloring-triangular MoTe2 monolayers

    Polymorphic structures of transition metal dichalcogenides (TMDs) host exotic electronic states, like charge density wave and superconductivity. However, the number of these structures is limited by crystal sy...

    Le Lei, Jiaqi Dai, Haoyu Dong, Yanyan Geng, Feiyue Cao, Cong Wang in Nature Communications (2023)

  6. Article

    Open Access

    MSFC: a new feature construction method for accurate diagnosis of mass spectrometry data

    Mass spectrometry technology can realize dynamic detection of many complex matrix samples in a simple, rapid, compassionate, precise, and high-throughput manner and has become an indispensable tool in accurate...

    **n Feng, Zheyuan Dong, Yingrui Li, Qian Cheng, Yongxian **n in Scientific Reports (2023)

  7. Article

    Open Access

    Real-time and accurate estimation of surgical hemoglobin loss using deep learning-based medical sponges image analysis

    Real-time and accurate estimation of surgical hemoglobin (Hb) loss is essential for fluid resuscitation management and evaluation of surgical techniques. In this study, we aimed to explore a novel surgical Hb ...

    Kai Li, Zexin Cheng, Junjie Zeng, Ying Shu, **aobo He, Hui Peng in Scientific Reports (2023)

  8. Article

    Open Access

    Author Correction: Numerical study of ice loads on different interfaces based on cohesive element formulation

    Wenqiang **ng, Shengyi Cong, **anzhang Ling, **nyu Li, Zhihe Cheng in Scientific Reports (2023)

  9. Article

    Open Access

    A novel subspace outlier detection method by entropy-based clustering algorithm

    Subspace outlier detection has emerged as a practical approach for outlier detection. Classical full space outlier detection methods become ineffective in high dimensional data due to the “curse of dimensional...

    Zheng Zuo, Ziqiang Li, Pengsen Cheng, Jian Zhao in Scientific Reports (2023)

  10. Article

    Open Access

    Myxobacteria restrain Phytophthora invasion by scavenging thiamine in soybean rhizosphere via outer membrane vesicle-secreted thiaminase I

    Public metabolites such as vitamins play critical roles in maintaining the ecological functions of microbial community. However, the biochemical and physiological bases for fine-tuning of public metabolites in...

    Chengyao **a, Yuqiang Zhao, Lei Zhang, Xu Li, Yang Cheng in Nature Communications (2023)

  11. Article

    Open Access

    Numerical study of ice loads on different interfaces based on cohesive element formulation

    With the increase of marine activities in the Arctic area, the demand for reliable design of marine structures is growing. Numerous publications can be found regarding simulations of ice action on structures u...

    Wenqiang **ng, Shengyi Cong, **anzhang Ling, **nyu Li, Zhihe Cheng in Scientific Reports (2023)

  12. Article

    Open Access

    Characterization and anti-inflammatory effect of selenium-enriched probiotic Bacillus amyloliquefaciens C-1, a potential postbiotics

    A patented strain of Bacillus amyloliquefaciens C-1 in our laboratory could produce functional sodium selenite (Na2SeO3) under optimized fermentation conditions. With the strong stress resistance and abundant sec...

    ** Liu, Lu Shi, **nxin Ma, Si** Jiang, **nyao Hou, Pu Li, Yue Cheng in Scientific Reports (2023)

  13. Article

    Open Access

    Cancer-cell-secreted miR-204-5p induces leptin signalling pathway in white adipose tissue to promote cancer-associated cachexia

    Cancer-associated cachexia is a multi-organ weight loss syndrome, especially with a wasting disorder of adipose tissue and skeletal muscle. Small extracellular vesicles (sEVs) serve as emerging messengers to c...

    Yong Hu, Liu Liu, Yong Chen, **aohui Zhang, Haifeng Zhou, Sheng Hu in Nature Communications (2023)

  14. Article

    Open Access

    Polyelectrolyte elastomer-based ionotronic sensors with multi-mode sensing capabilities via multi-material 3D printing

    Stretchable ionotronics have drawn increasing attention during the past decade, enabling myriad applications in engineering and biomedicine. However, existing ionotronic sensors suffer from limited sensing cap...

    Caicong Li, Jianxiang Cheng, Yunfeng He, **angnan He, Ziyi Xu in Nature Communications (2023)

  15. Article

    Open Access

    Electrocatalyzed direct arene alkenylations without directing groups for selective late-stage drug diversification

    Electrooxidation has emerged as an increasingly viable platform in molecular syntheses that can avoid stoichiometric chemical redox agents. Despite major progress in electrochemical C−H activations, these aren...

    Zhipeng Lin, Uttam Dhawa, **aoyan Hou, Max Surke, Binbin Yuan in Nature Communications (2023)

  16. Article

    Open Access

    A global database for modeling tumor-immune cell communication

    Communications between tumor cells and surrounding immune cells help shape the tumor immunity continuum. Recent breakthroughs in high-throughput technologies as well as computational algorithms had reported ma...

    Yun** **e, Weiwei Zhou, **gyi Shi, Mengjia Xu, Zi**g Lin, Donghao Li in Scientific Data (2023)

  17. Article

    Open Access

    Satellite record reveals 1960s acceleration of Totten Ice Shelf in East Antarctica

    Wilkes Land and Totten Glacier (TG) in East Antarctica (EA) have been losing ice mass significantly since 1989. There is a lack of knowledge of long-term mass balance in the region which hinders the estimation...

    Rongxing Li, Yuan Cheng, Tian Chang, David E. Gwyther in Nature Communications (2023)

  18. Article

    Open Access

    Assessing the effectiveness of targeted poverty alleviation policies in **njiang, China

    To consolidate and expand the effective connection between the achievements of poverty alleviation in **njiang’s deeply impoverished areas and rural revitalization, it is necessary to study the effects and mec...

    Yujie Huang, **anke Huang, Ruiliang Li in Humanities and Social Sciences Communicati… (2023)

  19. Article

    Open Access

    TPO as an indicator of lymph node metastasis and recurrence in papillary thyroid carcinoma

    The objective of this study was to investigate the expression of thyroid peroxidase (TPO) in papillary thyroid carcinoma (PTC) and to preliminarily investigate its value as a marker of lymph node metastasis an...

    **ang Li, Ruochuan Cheng in Scientific Reports (2023)

  20. Article

    Open Access

    Author Correction: Iontronic pressure sensor with high sensitivity over ultra-broad linear range enabled by laser-induced gradient micro-pyramids

    Ruoxi Yang, Ankan Dutta, Bowen Li, Naveen Tiwari, Wanqing Zhang in Nature Communications (2023)

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