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Article
Open AccessDisease-specific factors associated with cardiovascular events in patients with Takayasu arteritis
To identify disease-specific factors associated with cardiovascular events in patients with Takayasu arteritis (TAK).
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Article
Open AccessNon-histologic factors discriminating proliferative lupus nephritis from membranous lupus nephritis
To investigate non-histologic factors that can discriminate proliferative lupus nephritis (LN) from membranous LN in patients with systemic lupus erythematosus with renal manifestations.
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Article
Development and clinical study of the use of infrared radiation to accelerate the dissolution rate of a microneedle array patch (MAP)
The dissolution rate of a microneedle array patch (MAP) determines how long a MAP must remain attached to the skin (often called “wear time”). In this study, the dissolution rate of a MAP was increased, not by...
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Article
Microneedle Array Patch (MAP) Consisting of Crosslinked Hyaluronic Acid Nanoparticles for Processability and Sustained Release
Crosslinked hyaluronic acid (X-linked HA) is not suitable for making microneedles because of the low fluidity of X-linked HA hydrogel. Microneedles were fabricated using X-linked HA nanoparticles (X-linked HA-...
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Article
Dieckol or phlorofucofuroeckol extracted from Ecklonia cava suppresses lipopolysaccharide-mediated human breast cancer cell migration and invasion
The phlorotannin compounds, dieckol and phlorofucofuroeckol (PFF), extracted from Ecklonia cava, have been suggested to exhibit anti-inflammatory, anti-adipogenic or anti-tumorigenic activity. However, role of di...
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Chapter and Conference Paper
Automatic Design of 3D Lightweight Structures Based on Finite Element Mesh
In recent years, 3D printing has extended its applications from conventional prototy** to direct fabrication of functional parts. The advantage of 3D printing in its design flexibility and complexity has dri...
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Article
Topology Optimization and Additive Manufacturing of Customized Sports Item Considering Orthotropic Anisotropy
Topology optimization is a shape optimization method connected with finite element (FE) structural analysis, and has recently received increasing attention owing to rapid evolution of additive manufacturing (A...
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Article
Open AccessUtility of the Z-score of log-transformed A Body Shape Index (LBSIZ) in the assessment for sarcopenic obesity and cardiovascular disease risk in the United States
Body mass index (BMI) has limited accuracy for predicting cardiovascular diseases (CVD) and is not capable of identifying sarcopenic obesity, the combination of sarcopenia (an age-associated decline in muscle ...
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Article
Dissolving Microneedle Systems for the Oral Mucosal Delivery of Triamcinolone Acetonide to Treat Aphthous Stomatitis
A microneedle (MN) oral mucosal patch system was prepared to increase its adhesive strength, to improve the delivery of triamcinolone acetonide (TA) into the mucosa, and to protect the adhesive layer from mout...
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Article
Open AccessEffectiveness of Z-score of log-transformed A Body Shape Index (LBSIZ) in predicting cardiovascular disease in Korea: the Korean Genome and Epidemiology Study
Body mass index (BMI) and waist circumference (WC) have limitations in stratifying cardio-metabolic risks. Another obesity measure, A Body Shape Index (ABSI), has been introduced but its applicability remains ...
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Article
Automatic Design of 3D Conformal Lightweight Structures Based on a Tetrahedral Mesh
Recent developments of additive manufacturing (AM) have extended its application to the direct fabrication of functional parts. Owing to design flexibility and complexity, design for AM (DFAM) has received inc...
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Article
Efficacy of a bleomycin microneedle patch for the treatment of warts
Warts are a common skin disease caused by infection of the human papilloma virus. Most treatments involving physical destruction of the infected cells, such as cryotherapy and electrocautery, are limited by in...
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Article
Administration of a Sol-Gel Formulation of Phenylephrine Using Low-Temperature Hollow Microneedle for Treatment of Intermittent Fecal Incontinence
A low temperature hollow microneedle system was devised to deliver sol-gel transition formulation near the surface of the skin for extended release and local delivery of drug by a non-invasive method. This new...
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Article
Tat-DJ-1 enhances cell survival by inhibition of oxidative stress, NF-κB and MAPK activation in HepG2 cells
To identify the protective effect of DJ-1 protein against oxidative stress-induced HepG2 cell death, we used cell-permeable wild type (WT) and a mutant (C106A Tat-DJ-1) protein.
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Article
Open AccessTat-HSP22 inhibits oxidative stress-induced hippocampal neuronal cell death by regulation of the mitochondrial pathway
Oxidative stress plays an important role in the progression of various neuronal diseases including ischemia. Heat shock protein 22 (HSP22) is known to protect cells against oxidative stress. However, the prote...
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Article
Bleomycin-Coated Microneedles for Treatment of Warts
Bleomycin-coated microneedles were devised for delivery of bleomycin into the sub-epidermal skin layer for the treatment of warts in order to provide patient convenience and reduce patient pain and fear.
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Article
Open AccessTat-DJ-1 inhibits oxidative stress-mediated RINm5F cell death through suppression of NF-κB and MAPK activation
Oxidative stress is highly involved in the development of diabetes mellitus by destruction of pancreatic β-cells. DJ-1 is an antioxidant protein and DJ-1 expression levels are known to be reduced in diabetes m...
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Article
A portable electromagnetic induction heating device for point-of-care diagnostics
This paper introduces a portable magnetic field generator for producing wireless induction heating, which has recently been introduced as one of the major thermal techniques in the point-of-care (POC) diagnost...
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Article
Open AccessUrinary adiponectin and albuminuria in non-diabetic hypertensive patients: an analysis of the ESPECIAL trial
Although adiponectin levels have been reported to be correlated with albuminuria, this issue remains unresolved in non-diabetic hypertensive subjects, particularly when urinary adiponectin is considered.
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Article
Suppression of NF-κB by Dieckol Extracted from Ecklonia cava Negatively Regulates LPS Induction of Inducible Nitric Oxide Synthase Gene
Dieckol, extracted from brown algae, Ecklonia cava, is suggested to elicit anti-inflammatory or anti-tumorigenic activities. However, dieckol-mediated regulatory mechanism for inflammatory response still remains ...
