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Article
Open AccessThe effect of a biphasic injectable bone substitute on the interface strength in a rabbit knee prosthesis model
In joint prosthetic surgery, various methods are used to provide implant stability. We used an injectable bone substitute, composed of calcium sulfate/hydroxyapatite, as bone defect filler to stabilize a tibia...
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Article
Dissipative particle dynamics simulation of field-dependent DNA mobility in nanoslits
The dynamics of DNA molecules in highly confined nanoslits under varying electric fields are studied using dissipative particle dynamics method, and our results show that manipulation of the electrical field c...
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Article
Open AccessModified femoral pressuriser generates a longer lasting high pressure during cement pressurisation
The strength of the cement-bone interface in hip arthroplasty is strongly related to cement penetration into the bone. A modified femoral pressuriser has been investigated, designed for closer fitting into the...
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Article
Phonon Hall effect in ionic crystals in the presence of static magnetic field
We study phonon Hall effect (PHE) for ionic crystals in the presence of static magnetic field. Using Green-Kubo formula, we present an exact calculation of thermal conductivity tensor by considering both posi...
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Article
Open AccessGeneration of fusion protein EGFRvIII-HBcAg and its anti-tumor effect in vivo
The epidermal growth factor receptor variant III (EGFRvIII) is the most common variation of EGFR. Because it shows a high frequency in several different types of tumor and has not been detected in normal tissu...
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Article
Transport of biomolecules in asymmetric nanofilter arrays
We propose a theoretical model for describing the electric-field-driven migration of rod-like biomolecules in nanofilters comprising a periodic array of shallow passages connecting deep wells. The electrophore...
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Article
Dissipative particle dynamics simulations of electroosmotic flow in nano-fluidic devices
When modeling the hydrodynamics of nanofluidic systems, it is often essential to include molecular-level information such as molecular fluctuations. To this effect, we present a mesoscopic approach which combi...
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Chapter and Conference Paper
From CA to Gene Expression: Machines and Mechanisms
Molecular motors are proteins or macromolecular complexes which use input energy to perform mechanical work. Some of these motors move on filamentous proteins whereas other move on DNA or RNA strands. Often, m...
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Article
Technetium-99m-hexakis-2-methoxyisobutylisonitrile scintigraphy and multidrug resistance-related protein expression in human primary lung cancer
The occurrence of multidrug resistance (MDR) is a major cause of resistance to chemotherapeutic agents in patients with lung cancer, in part owing to the overexpression of MDR-related proteins. Technetium-99m-...
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Article
Factors affecting the static shear strength of the prosthetic stem–bone cement interface
Debonding of the stem–cement interface has been implicated in the initiation of failure of cemented femoral stems. The objective of this work was to examine some of the parameters which influence the interface...
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Chapter
Bone, Cement, and Metal Implant Interface Preparation with a High-Pressure Water Cutter
Today, many studies in cemented prostheses focus on the interface between bone and cement as well as between cement and stem. Extensive porosity is aggregated at the cement-stem interface in retrieved cement m...
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Chapter
Histomorphometric Analysis of Bone-Cement and Cement-Metal Interface
Bone cement primarily functions by filling the free space between the prosthesis and the bone. The connection between the cement and the bone and between the cement and the prosthesis has been repeatedly and i...
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Article
Modeling generalized stacking faults in Au using the tight-binding potential combined with a simulated annealing method
The tight-binding potential combined with a simulated annealing method is used to study the generalized stacking fault (GSF) structure and corresponding energy of gold. The potential is chosen to fit band stru...
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Chapter
Internal Hydrogen-induced Embrittlement in Iron Single Crystals
A thermodynamic model for internal hydrogen-induced embrittlement (HIE) in single crystals is proposed. The model is based on the assumption that the ductile versus brittle transition is controlled by the comp...
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Article
Transition Matrix Monte Carlo Method
We present a formalism of the transition matrix Monte Carlo method. A stochastic matrix in the space of energy can be estimated from Monte Carlo simulation. This matrix is used to compute the density of states...
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Chapter and Conference Paper
Efficient Monte Carlo Simulation Methods in Statistical Physics
The basic problem in equilibrium statistical mechanics is to compute phase space average, in which Monte Carlo method plays a very important role. We begin with a review of nonlocal algorithms for Markov chain...
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Chapter and Conference Paper
Bone Cement Porosity in Vacuum Mixing Systems
It is believed that the porosity of orthopedic bone cement influences the long-term mechanical stability and thus survival of joint prostheses. Various studies have shown that pores within the cement are detri...
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Chapter and Conference Paper
Ising Relaxation Dynamics: Series Expansion and Monte Carlo Simulation
The critical relaxation of the 2D Ising model is studied by series expansion in time t and by Monte Carlo simulation. Estimates from a 12-th order series Padé analysis for the dynamical critical exponent are comp...
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Article
Why L12 intermetallics are brittle and how to make them ductile
Origins of the intrinsic and extrinsic brittleness of L12 intermetallics are analyzed. It is shown that the intrinsic behavior is determined by the dislocation process in the alloy, and that the extrinsic behavio...
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Article
Anisotropic finite-size scaling analysis of a two-dimensional driven diffusive system
The standard two-dimensional uniformly driven diffusive model is simulated extensively for much larger systems with a multi-spin coding technique. The nonequilibrium phase transition is analyzed with anisotrop...
