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  1. Article

    Open Access

    Pancreaticoduodenectomy with reconstructing blood flow of the gastric conduit after esophagectomy with concomitant celiac axis stenosis: a case report

    Pancreaticoduodenectomy after esophageal resection is technically difficult, because blood flow of the gastric conduit should be preserved. Celiac axis stenosis (CAS) is also a problem for pancreaticoduodenect...

    Masaaki Minagawa, Hirofumi Ichida, Ryuji Yoshioka, Yu Gyoda in Surgical Case Reports (2020)

  2. Article

    Prognostic value of postoperative C-reactive protein elevation versus complication occurrence: a multicenter validation study

    Several studies have shown that postoperative complications worsen the prognosis of patients with malignancies. However, our previous study showed that C-reactive protein (CRP) elevation over 12 mg/dL was a mo...

    Yukinori Kurokawa, Kotaro Yamashita, Ryohei Kawabata, Junya Fujita in Gastric Cancer (2020)

  3. No Access

    Article

    Significance of fistulography findings to the healing time of postoperative pancreatic fistula after pancreaticoduodenectomy

    Pancreatic fistula (PF) is a common and serious complications after pancreaticoduodenectomy (PD). However, few studies have discussed the time required for PF healing in patients with this complication. This s...

    Yoshito Tomimaru, Kaishu Tanaka, Kozo Noguchi, Shing o Noura in Surgery Today (2020)

  4. No Access

    Article

    Efficacy and feasibility of S-1 plus oxaliplatin (C-SOX) for treating patients with stage III colon cancer (KSCC1303): final analysis of 3-year disease-free survival

    Adjuvant chemotherapy is an accepted treatment to improve survival rates in patients with stage III colon cancer, and regimens including oxaliplatin have been shown to be superior to those containing 5-FU alon...

    Koji Ando, Yasunori Emi, Nobutomo Miyanari in International Journal of Clinical Oncology (2020)

  5. Article

    Open Access

    Beneficial effect modification on survival outcome of sepsis between ART-123 and polymyxin B‑immobilised haemoperfusion: a nationwide Japanese registry study

    Although recently published randomised controlled trials did not confirm significant positive effect of ART-123 or polymyxin B‑immobilised haemoperfusion (PMX-HP) on survival outcome, previous studies using a ...

    Katsunori Mochizuki, Kotaro Mori, Hiroshi Kamijo in Annals of Intensive Care (2020)

  6. Article

    Five-year outcomes of a phase II study of adjuvant chemotherapy with S-1 plus docetaxel for stage III gastric cancer after curative D2 gastrectomy (OGSG1002)

    Adjuvant S-1 monotherapy is standard of care for stage II and III gastric cancer (GC), but there is still a need to improve the efficacy of treatment for stage III disease. We conducted phase II study of eight...

    Kazumasa Fujitani, Shigeyuki Tamura, Yutaka Kimura, ** Matsuyama in Gastric Cancer (2020)

  7. No Access

    Article

    Predictive Factors of Postoperative Delirium in Patients After Pancreaticoduodenectomy

    Postoperative delirium is a common serious complication after various types of surgery. However, the incidence and predictive factors associated with delirium after pancreaticoduodenectomy (PD) have not been i...

    Yoshito Tomimaru, Sung Ae Park, Asuka Shibata in Journal of Gastrointestinal Surgery (2020)

  8. No Access

    Article

    Clinical investigation of the cystic duct variation based on the anatomy of the hepatic vasculature

    Anatomical variation of the cystic duct (CD) is rare but can result in misunderstanding of the CD anatomy during laparoscopic cholecystectomy, potentially leading to bile duct injury. Therefore, the precise pr...

    Naoto Fujimoto, Yoshito Tomimaru, Takamori Yamamoto, Yuto Hayashi in Surgery Today (2020)

  9. Article

    Open Access

    A comprehensive protocol for ventilator weaning and extubation: a prospective observational study

    Ventilator weaning protocols have been shown to reduce the duration of mechanical ventilation (MV), intensive care unit length of stay, and resource use. However, weaning protocols have not significantly affec...

    Kenichi Nitta, Kazufumi Okamoto, Hiroshi Imamura in Journal of Intensive Care (2019)

  10. Article

    An integrated analysis of two phase II trials (JCOG0001 and JCOG0405) of preoperative chemotherapy followed by D3 gastrectomy for gastric cancer with extensive lymph node metastasis

    Gastric cancer with extensive lymph node metastasis is commonly regarded as unresectable, while preoperative chemotherapy followed by gastrectomy has been tested since 2000 in JCOG (JCOG0001 and JCOG0405). The...

    Hiroshi Katayama, Akira Tsuburaya, Junki Mizusawa, Kenichi Nakamura in Gastric Cancer (2019)

  11. Article

    Early tumor shrinkage and depth of response in patients with advanced gastric cancer: a retrospective analysis of a randomized phase III study of first-line S-1 plus oxaliplatin vs. S-1 plus cisplatin

    We investigated early tumor shrinkage (ETS) and depth of response (DpR) using data from the G-SOX study comparing S-1 plus oxaliplatin with S-1 plus cisplatin as the first-line treatment for advanced gastric c...

    Tomohiro Nishina, Mizutomo Azuma, Kazuhiro Nishikawa, Masahiro Gotoh in Gastric Cancer (2019)

  12. No Access

    Chapter

    Respiratory Tract Burns, Traumatic Pulmonary Contusions, Crushing Death, and Crush Syndrome: What Kinds of Lung Injury Occur by Respiratory Tract Burn, Traumatic Contusion, and Crush Syndrome?

    Various types of respiratory system injury can occur in a disaster setting, including traumatic thoracic injury, traumatic asphyxia, and inhalation injury. Further, multi-system injuries may occur in combinati...

    Hiroshi Imamura in Disaster and Respiratory Diseases (2019)

  13. No Access

    Article

    Is Intraoperative Blood Loss Underestimated in Patients Undergoing Laparoscopic Hepatectomy?

    Less intraoperative blood loss is frequently reported as an advantage of laparoscopic hepatectomy (LH) over open hepatectomy (OH). However, the small work space during laparoscopic surgery could lead to insuff...

    Yoshito Tomimaru, Kozo Noguchi, Shunji Morita, Hiroshi Imamura in World Journal of Surgery (2018)

  14. Article

    Open Access

    A case of intraductal papillary-mucinous neoplasm of the pancreas penetrating into the stomach and spleen successfully treated by total pancreatectomy

    Intraductal papillary-mucinous neoplasms (IPMNs) are potentially malignant intraductal epithelial neoplasms that sometimes penetrate into other organs. To the best of our knowledge, no report has yet described...

    Takashi Harino, Yoshito Tomimaru, Kozo Noguchi, Hirotsugu Nagase in Surgical Case Reports (2018)

  15. No Access

    Article

    Cardiac hyaluronan may be associated with the persistence of atrial fibrillation

    Hyaluronan (HA), a primary component of the extracellular matrix, is associated with several cardiovascular diseases. However, its precise cardiac origin and role in atrial fibrillation (AF) remain unclear. We...

    Ayako Okada, Yuichiro Kashima, Takeshi Tomita, Takahiro Takeuchi in Heart and Vessels (2017)

  16. Article

    Impact of progression type on overall survival in patients with advanced gastric cancer based on randomized phase III study of S-1 plus oxaliplatin versus S-1 plus cisplatin

    The association between progression type and survival has been reported in breast cancer, but remains unclear in advanced gastric cancer (AGC). Here, this association was assessed using data obtained from an e...

    Kazuhiro Nishikawa, Yasuhide Yamada, Kenji Ishido, Masahiro Gotoh in Gastric Cancer (2017)

  17. Article

    Open Access

    Impact of insulin-like growth factor-1 receptor and amphiregulin expression on survival in patients with stage II/III gastric cancer enrolled in the Adjuvant Chemotherapy Trial of S-1 for Gastric Cancer

    Exploratory biomarker analysis was conducted to identify factors related to the outcomes of patients with stage II/III gastric cancer using data from the Adjuvant Chemotherapy Trial of S-1 for Gastric Cancer, ...

    Wataru Ichikawa, Masanori Terashima, Atsushi Ochiai, Koji Kitada in Gastric Cancer (2017)

  18. No Access

    Article

    Primary surgery as a frontline treatment for synchronous metastatic gastrointestinal stromal tumors: an analysis of the Kinki GIST registry

    To investigate the outcomes of a combined treatment regimen comprising primary surgery and tyrosine kinase inhibitor (TKI) therapy for synchronous metastatic gastrointestinal stromal tumors (GIST).

    Shinsuke Sato, Toshimasa Tsu**aka, Kazuyoshi Yamamoto, Tsuyoshi Takahashi in Surgery Today (2016)

  19. No Access

    Article

    Meta-analysis supporting noninferiority of oxaliplatin plus S-1 to cisplatin plus S-1 in first-line treatment of advanced gastric cancer (G-SOX study): indirect comparison with S-1 alone

    The Randomized Phase III Study Comparing Oxaliplatin plus S-1 with Cisplatin plus S-1 in Chemotherapy-naïve Patients with Advanced Gastric Cancer (G-SOX) showed the noninferiority of S-1 (an oral fluoropyrimid...

    Chikuma Hamada, Yasuhide Yamada in International Journal of Clinical Oncology (2016)

  20. No Access

    Article

    Randomized Controlled Trial for Evaluation of the Routine Use of Nasogastric Tube Decompression After Elective Liver Surgery

    The value of routine nasogastric tube (NGT) decompression after elective hepatetctomy is not yet established. Previous studies in the setting of non-liver abdominal surgery suggested that the use of NGT decrea...

    Hirofumi Ichida, Hiroshi Imamura, Jiro Yoshimoto in Journal of Gastrointestinal Surgery (2016)

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