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Article
Open AccessAging of blood can be tracked by DNA methylation changes at just three CpG sites
Human aging is associated with DNA methylation changes at specific sites in the genome. These epigenetic modifications may be used to track donor age for forensic analysis or to estimate biological age.
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Article
Quantifizierung der Telomerlängen in Granulozyten und Lymphozyten
Telomere length of peripheral blood granulocytes and lymphocytes is frequently used to estimate the remaining replicative potential of the corresponding hematopoietic stem and progenitor cells. Flow-cytometry ...
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Article
Identification of CD133−/Telomeraselow Progenitor Cells in Glioblastoma-Derived Cancer Stem Cell Lines
Glioblastoma multiforme (GBM) is paradigmatic for the investigation of cancer stem cells (CSC) in solid tumors. The CSC hypothesis implies that tumors are maintained by a rare subpopulation of CSC that gives r...
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Article
Open AccessPapillary thyroid cancer associated with syndrome of inappropriate antidiuresis: a case report
The syndrome of inappropriate antidiuresis is the most common cause of euvolemic hypo-osmolality. This syndrome is associated with a wide variety of diseases. However, its most frequent causes are related to m...