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Article
Open AccessNephrometry score-guided off-clamp laparoscopic partial nephrectomy: patient selection and short-time functional results
Laparoscopic partial nephrectomy (LPN) is not a novel but a relatively technically challenging surgical procedure. Off-clamp LPN with zero ischemia can completely eliminate ischemic reperfusion injury to the k...
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Article
Pretreatment neutrophil-to-lymphocyte ratio predicts prognosis in patients with metastatic renal cell carcinoma receiving targeted therapy
The neutrophil-to-lymphocyte ratio (NLR) is associated with clinical outcomes of various cancers. This study aimed to evaluate whether pretreatment NLR can be used as a prognostic factor in patients with metas...
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Article
Extent of pelvic lymph node dissection in penile cancer may impact survival
Current guidelines on management of penile carcinoma (PC) recommend ipsilateral pelvic lymph node dissection (PLND) in patients with inguinal lymph node metastasis (LNM) who meet specific criteria. The aim of ...
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Article
Open AccessEffect of Body mass index on the performance characteristics of PSA-related markers to detect prostate cancer
To examine whether the predictive performance of prostate-specific antigen (PSA) and PSA-related markers for prostate cancer (PCa) is modified by body mass index (BMI). Patients with a PSA 2–10 ng/mL who under...
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Article
Preoperative lymphocyte-monocyte and platelet-lymphocyte ratios as predictors of overall survival in patients with bladder cancer undergoing radical cystectomy
Although pretreatment neutrophil–lymphocyte ratio (NLR), lymphocyte–monocyte ratio (LMR), and platelet–lymphocyte ratio (PLR) are reportedly associated with clinical outcomes of many cancers, their roles in pa...
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Article
Open AccessDevelopment and external validation of a prostate health index-based nomogram for predicting prostate cancer
To develop and externally validate a prostate health index (PHI)-based nomogram for predicting the presence of prostate cancer (PCa) at biopsy in Chinese men with prostate-specific antigen 4–10 ng/mL and norma...
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Article
Evaluation of fine particles in surgical smoke from an urologist’s operating room by time and by distance
Electrocautery, harmonic scalpel tissue dissection and other surgical techniques can generate surgical smoke with high proportion of ‘fine particles’ (PM2.5) <2.5 μm, which is known to have adverse effects on hum...
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Article
Open AccessImpact of preoperative 5α-reductase inhibitors on perioperative blood loss in patients with benign prostatic hyperplasia: a meta-analysis of randomized controlled trials
The ability of 5α-reductase inhibitors (5ARIs) to decrease blood loss during transurethral resection of the prostate (TURP) for benign prostatic hyperplasia (BPH) remains controversial. We aimed to conduct a m...
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Article
Alkaline phosphatase velocity in nonmetastatic CRPC
Few prognostic factors have been identified and successfully replicated for patients with high-risk nonmetastatic castration-resistant prostate cancer (nmCRPC). However, a new report has shown that alkaline ph...
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Article
Down-regulation of Dicer and Ago2 is associated with cell proliferation and apoptosis in prostate cancer
Dicer and Argonaute2 (Ago2) are critical components responsible not only for RNA interference but also for microRNA synthesis. The present study investigated the roles of Dicer and Ago2 in prostate cancer (Pca...
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Article
Open AccessMetabolic syndrome and renal cell carcinoma
Metabolic syndrome (MS) is a cluster of metabolic abnormalities, which has been regarded as a pivotal risk factor for cardiovascular diseases. Recent studies focusing on the relationship between MS and cancer ...
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Article
Open AccessTesticular desmoplastic small round cell tumor: a case report and review of literature
Desmoplastic small round cell tumor (DSRCT) is an uncommon and highly aggressive malignancy with undetermined histogenesis and poor prognosis. To date, no case of testicular DSRCT has been reported in the lite...
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Article
Validation of the prognostic value of lymph node ratio in patients with penile squamous cell carcinoma: a population-based study
The aim of this study was to validate the prognostic value of lymph node ratio (LNR), the proportion of metastatic among removed lymph nodes, for patients with penile squamous cell carcinoma in a population-ba...
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Article
Development of a nomogram to predict non-organ-confined bladder urothelial cancer before radical cystectomy
To create a preoperative prediction model for estimating the risk of non-organ-confined (pT3-4 or pN+) bladder urothelial cancer (NOC–BUC) in patients with clinically OC–BUC (cT1-2N0M0).
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Article
Open AccessPrimary yolk sac tumor of seminal vesicle: a case report and literature review
Yolk sac tumor (endodermal sinus tumor) is a rare malignant germ cell tumor arising in the testis or ovary. Extragonadal yolk sac tumor is even rarer and has only been described in case reports. Due to the rar...
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Article
Lymph node metastases and prognosis in penile cancer
Lymph node status is a key prognostic factor in penile squamous cell carcinoma. Recently, growing evidence indicates a multimodality approach consisting of neoadjuvant chemotherapy followed by consolidation su...
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Article
Narrow-band imaging flexible cystoscopy in the detection of primary non-muscle invasive bladder cancer: a “second look” matters?
We investigated whether narrow-band imaging (NBI) was superior to white light imaging (WLI) for detecting primary non-muscle invasive bladder cancer (NMIBC) in a randomized imaging sequence modality, as the in...
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Article
Open AccessYolk sac tumor in a patient with transverse testicular ectopia
Transverse testicular ectopia (TTE) is a rare anomaly in which both testes descend through a single inguinal canal. We report a case of yolk sac tumor in the ectopic testis of a patient with TTE. A 24-year-old...
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Article
Involvement of microRNA-21 in mediating chemo-resistance to docetaxel in androgen-independent prostate cancer PC3 cells
To investigate whether microRNA-21 was involved in mediating the chemoresistance of prostate cancer cells to docetaxel.