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  1. No Access

    Article

    PIK3R2 predicts poor outcomes for patients with melanoma and contributes to the malignant progression via PI3K/AKT/NF-κB axis

    Melanoma is an aggressive form of skin cancer worldwide. Phosphoinositide-3-kinase regulatory subunit 2 (PIK3R2) exerts carcinogenic roles in various tumors. So far, the function and mechanism of PIK3R2 in me...

    Jianguo Wang, Shizhong Cai, Qianwei **ong, Deyu Weng in Clinical and Translational Oncology (2023)

  2. Article

    Open Access

    Eosinophilic solid and cystic renal cell carcinoma with TSC2 mutation: a case report and literature review

    Eosinophilic solid and cystic renal cell carcinoma (ESC-RCC) is an under-recognized, emerging new entity of sporadic renal neoplasms, which is listed as a rare type of renal cell carcinoma in the 2022 WHO rena...

    **n He, Ying Chen, Hao Tang, Yujuan Xu, **ngyan Zhu, Caihong Wang in Diagnostic Pathology (2023)

  3. Article

    Open Access

    Acinar cell carcinoma of gastric ectopic pancreas origin: a case report and literature review

    Primary pancreatic-type acinar cell carcinoma of the stomach is extremely rare, often misdiagnosed, and of unclear origin.

    Ying Chen, Ning Zhou, Deyu Guo, **n He, Hao Tang, Lina Wang in Diagnostic Pathology (2023)

  4. Article

    Open Access

    Neuroendocrine differentiation: a risk fellow in colorectal cancer

    Neuroendocrine differentiation (NED) is often found in colorectal cancer (CRC) and may have unique biological behavior, which has not been previously delineated. Here, we explore the relationship between CRC, ...

    Yue Chen, Yu Liang, Lianqun Cao, **nxin Dong in World Journal of Surgical Oncology (2023)

  5. Article

    Open Access

    Dlk1 maintains adult mice long-term HSCs by activating Notch signaling to restrict mitochondrial metabolism

    Adult hematopoietic stem cells (HSCs) homeostasis is critically important in maintaining lifelong hematopoiesis. However, how adult HSCs orchestrate its homeostasis remains not fully understood. Imprinted gene...

    Deyu Huang, Yingli Han, Tian Tang, Lin Yang in Experimental Hematology & Oncology (2023)

  6. Article

    Open Access

    Sinonasal mucosal melanoma with smooth muscle differentiation: a potential pathological diagnostic pitfall

    Sinonasal mucosal melanoma (SNMM) is a rare malignant melanoma originating from melanocytes derived from multipotent neural crest cells. Its incidence accounts for less than 1 % of all malignant melanomas, wit...

    Hao Tang, Yutao He, Ying Chen, Wenfeng Xu, Yujuan Xu, **anyun Li in Diagnostic Pathology (2022)

  7. Article

    Open Access

    Prognostic value of elastic lamina staining in patients with stage III colon cancer

    The objectives of this study were to analyze the difference between the preoperative radiological and postoperative pathological stages of colorectal cancer (CRC) and explore the feasibility of elastic lamina ...

    Feifei Bi, **aoyan Li, Yong Zhang, Zekun Wang in World Journal of Surgical Oncology (2022)

  8. Article

    Open Access

    Comparison of the duration of viral RNA shedding and anti-SARS-CoV-2 spike IgG and IgM antibody titers in COVID-19 patients who were vaccinated with inactivated vaccines or not: a retrospective study

    At present, the role of inactivated vaccines in viral RNA shedding among Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) breakthrough infections is still unknown.

    Chuancai Xu, Zhisong He, Wei Lei, Li Chen, Dan Shen in BMC Infectious Diseases (2022)

  9. No Access

    Article

    A retrospective analysis of transanal surgical management of 291 cases with rectal foreign bodies

    Rectal foreign bodies (RFB) are quite uncommon except in very busy hospitals. Because of their rarity, it is seldom that the treating physicians have a standard approach to the diagnosis, technique of extracti...

    Yong Zhang, Yi Han, Huimian Xu, Deyu Chen in International Journal of Colorectal Disease (2022)

  10. Article

    Open Access

    Chimeric antigen receptor T-cell therapy for relapsed and refractory thyroid cancer

    The prognosis of most thyroid cancer patients is excellent, but for those with advanced or metastatic thyroid cancer, effective treatments are still lacking. Chimeric antigen receptor (CAR) T-cell therapy has ...

    **g Ding, Deyu Li, **ngchen Liu, Hu Hei, Baoxi Sun in Experimental Hematology & Oncology (2022)

  11. Article

    Open Access

    An updated RBD-Fc fusion vaccine booster increases neutralization of SARS-CoV-2 Omicron variants

    Deyan Luo, **aolan Yang, Tao Li, Nianzhi Ning in Signal Transduction and Targeted Therapy (2022)

  12. Article

    Open Access

    Predominantly epithelial-type synovial sarcoma with overwhelming neuroendocrine differentiation: a potential diagnostic pitfall

    Synovial sarcoma is an uncommon soft tissue tumor of soft tissue, characterized by a specific SS18 rearrangement. It generally manifests as a lesion composed of monomorphic spindle cells and sometimes shows va...

    Ying Chen, Ning Zhou, Deyu Guo, **aodong Wang, **n He, Yujuan Xu in Diagnostic Pathology (2022)

  13. Article

    Open Access

    Acetyl-CoA synthetase 2(ACSS2): a review with a focus on metabolism and tumor development

    Acetyl-CoA synthetase 2 (ACSS2), an important member of the acetyl-CoA synthetase (ACSS) family, can catalyze the conversion of acetate to acetyl coenzyme A (acetyl-CoA). Currently, acetyl-CoA is considered an...

    Rui Ling, Gong Chen, **ang Tang, Na Liu, Yuepeng Zhou, Deyu Chen in Discover Oncology (2022)

  14. No Access

    Article

    Can echocardiographic assessment of diastolic function be automated?

    Echocardiographic evaluation of left ventricular diastolic function relies on a multi-pronged algorithm, which incorporates Doppler-based and volumetric parameters. Integration of clinical data in diastolic as...

    Amita Singh, Deyu Sun, Victor Mor-Avi in The International Journal of Cardiovascula… (2022)

  15. Article

    Open Access

    Aptamer blocking S-TLR4 interaction selectively inhibits SARS-CoV-2 induced inflammation

    Gang Yang, Shengnan Zhang, Yuchun Wang, Ling Li in Signal Transduction and Targeted Therapy (2022)

  16. Article

    Open Access

    Laparoscopic versus open reduction of idiopathic intussusception in children: an updated institutional experience

    In the reduction of intussusception, due to the lack of randomized, controlled, and prospective clinical trials to confirm the superiority of the laparoscopic approach over open surgery, more evidence was need...

    Jian Zhao, Jun Sun, Deyu Li, Wei Jue Xu in BMC Pediatrics (2022)

  17. Article

    Open Access

    Success of small-dose fractionated sodium thiosulfate in the treatment of calciphylaxis in a peritoneal dialysis patient

    Calciphylaxis, or calcific uremic arteriolopathy (CUA), is a rare, fatal disorder of microvascular calcification and thrombosis that typically affects patients with end-stage renal disease (ESRD) receiving lon...

    Yuan Lu, Lei Shen, Ling Zhou, Deyu Xu in BMC Nephrology (2022)

  18. Article

    Open Access

    Characterization of gut microbiome in mice model of depression with divergent response to escitalopram treatment

    Depression is a common and heterogeneous mental disorder. Although several antidepressants are available to treat the patients with depression, the factors which could affect and predict the treatment response...

    Jiajia Duan, Yu Huang, Xunmin Tan, Tingjia Chai, **g Wu in Translational Psychiatry (2021)

  19. Article

    Open Access

    miR-122-5p regulates the tight junction of the blood-testis barrier of mice via occludin

    Occludin protein is the primary assembling protein of TJs and the structural basis for tight junction formation between Sertoli cells in the spermatogenic epithelium. The expression of miR-122-5p and occludin ...

    Limin Liu, Maoying Zhu, **aoli Liu, Lumin Fei, Jianyun Shen in Basic and Clinical Andrology (2021)

  20. No Access

    Article

    Metabolism and immunity in breast cancer

    Breast cancer is one of the most common malignancies that seriously threaten women’s health. In the process of the malignant transformation of breast cancer, metabolic reprogramming and immune evasion represen...

    Deyu Zhang, **aojie Xu, Qinong Ye in Frontiers of Medicine (2021)

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