158 Result(s)
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Open AccessThe Presence of Diabetes Mellitus or Pre-diabetes Mellitus Increases Mortality from Heart Disease in a Taiwanese Population: A 10-year Follow-Up Study
We evaluated hyperglycemia-associated mortality in the Taiwanese population by conducting a 10-year retrospective cohort study. Methods: From 2007 to 2017, all participants, regardless of their age or underlyi...
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Open AccessA chromosome-level genome assembly of Hong Kong catfish (Clarias fuscus) uncovers a sex-determining region
Hong Kong catfish (Clarias fuscus) is an ecologically and economically important species that is widely distributed in freshwater regions of southern China. Hong Kong catfish has significant sexual growth dimorph...
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Open AccessColonization with ubiquitous protist Blastocystis ST1 ameliorates DSS-induced colitis and promotes beneficial microbiota and immune outcomes
Blastocystis is a species complex that exhibits extensive genetic diversity, evidenced by its classification into several genetically distinct subtypes (ST). Although several studies have shown the relationships ...
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Open AccessAn intranasal influenza virus-vectored vaccine prevents SARS-CoV-2 replication in respiratory tissues of mice and hamsters
Current available vaccines for COVID-19 are effective in reducing severe diseases and deaths caused by SARS-CoV-2 infection but less optimal in preventing infection. Next-generation vaccines which are able to ...
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Open AccessOTUB1 promotes osteoblastic bone formation through stabilizing FGFR2
Bone homeostasis is maintained by the balance between osteoblastic bone formation and osteoclastic bone resorption. Dysregulation of this process leads to multiple diseases, including osteoporosis. However, th...
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Open AccessParental hesitancy against COVID-19 vaccination for children and associated factors in Taiwan
Since July 2021, some countries and regions have initiated the vaccination of minors against coronavirus disease (COVID-19), and parental COVID-19 vaccine hesitancy will affect the vaccination of minors. We ai...
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Open AccessComprehensive prognostic effects of systemic inflammation and Insulin resistance in women with breast cancer with different BMI: a prospective multicenter cohort
To investigate the prognostic value of systemic inflammation and insulin resistance in women with breast cancer with different body mass index (BMI). This multicenter, prospective study included 514 women with...
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Retraction Note: Cognitive learning performance assessment and analysis with CSCL applied on the NetGuru platform and CSPL applied on the TAoD platform for the network experiment class
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Open AccessThe development of a cSMART-based integrated model for hepatocellular carcinoma diagnosis
Hepatocellular carcinoma (HCC) generally arises from a background of liver cirrhosis (LC). Patients with cirrhosis and suspected HCC are recommended to undergo serum biomarker tests and imaging diagnostic eval...
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Open AccessLong-term presence of autoantibodies in plasma of cured leprosy patients
Autoantibodies have been detected in leprosy patients, indicating that infection with M. leprae may lead to autoimmune disorders. However, whether autoimmune response last until patients are cured is unknown. Kno...
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Open AccessAGA induces sub-G1 cell cycle arrest and apoptosis in human colon cancer cells through p53-independent/p53-dependent pathway
Despite the advancement in chemotherapeutic drugs for colon cancer treatment, it is still a life-threatening disease worldwide due to drug resistance. Therefore, an urgently needed to develop novel drugs for c...
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Open AccessSpectrum of the S-wave fully-heavy tetraquark states
In present work, spectrum of the S-wave fully-heavy tetraquark states \(QQ\bar{Q}\bar{Q}\) ...
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Open AccessCorrection: CRISPR FISHer enables high-sensitivity imaging of nonrepetitive DNA in living cells through phase separation-mediated signal amplification
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Open AccessDifferential transcriptomic landscapes of multiple organs from SARS-CoV-2 early infected rhesus macaques
SARS-CoV-2 infection causes complicated clinical manifestations with variable multi-organ injuries, however, the underlying mechanism, in particular immune responses in different organs, remains elusive. In th...
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Open AccessTargeting UHRF1-SAP30-MXD4 axis for leukemia initiating cell eradication in myeloid leukemia
Aberrant self-renewal of leukemia initiation cells (LICs) drives aggressive acute myeloid leukemia (AML). Here, we report that UHRF1, an epigenetic regulator that recruits DNMT1 to methylate DNA, is highly exp...
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Open AccessAccuracy of calculating mechanical power of ventilation by one commonly used equation
Gattinoni’s equation, $${\text{MP}}_{{{\text{rs}}}} \, = \,0.098\, \times \,{\text{RR}}\, \times \,\left[ {{\text{V}}_{T} ^{2} \left( {\frac{1...
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Fungal diversity notes 1512–1610: taxonomic and phylogenetic contributions on genera and species of fungal taxa
This article is the 14th in the Fungal Diversity Notes series, wherein we report 98 taxa distributed in two phyla, seven classes, 26 orders and 50 families which are described and illustrated. Taxa in this stu...
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Open AccessCRISPR FISHer enables high-sensitivity imaging of nonrepetitive DNA in living cells through phase separation-mediated signal amplification
The dynamic three-dimensional structures of chromatin and extrachromosomal DNA molecules regulate fundamental cellular processes and beyond. However, the visualization of specific DNA sequences in live cells, ...
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Article
Open AccessThe low-lying hidden- and double-charm tetraquark states in a constituent quark model with instanton-induced interaction
Spectrum of the low-lying hidden- and double-charm tetraquark states are investigated in a nonrelativistic quark potential model, where the instanton-induced interaction is taken as the residual spin-dependent...
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Design and application of a multichannel “cross” hot tearing tendency device: A study on hot tearing tendency of Al alloys
Hot tearing is one of the most serious defects during the casting solidification process. In this study, a new type of multichannel “cross” hot tearing device was designed. The hot cracks initiation and propag...