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  1. Article

    Open Access

    The Presence of Diabetes Mellitus or Pre-diabetes Mellitus Increases Mortality from Heart Disease in a Taiwanese Population: A 10-year Follow-Up Study

    We evaluated hyperglycemia-associated mortality in the Taiwanese population by conducting a 10-year retrospective cohort study. Methods: From 2007 to 2017, all participants, regardless of their age or underlyi...

    Hsuan-Chih Tsai, Po-Sheng Hsu, Lung-Fa Pan, Chia-Lien Hung in BMC Cardiovascular Disorders (2023)

  2. Article

    Open Access

    A chromosome-level genome assembly of Hong Kong catfish (Clarias fuscus) uncovers a sex-determining region

    Hong Kong catfish (Clarias fuscus) is an ecologically and economically important species that is widely distributed in freshwater regions of southern China. Hong Kong catfish has significant sexual growth dimorph...

    Chang-Xu Tian, **ng-Hua Lin, Da-Yan Zhou, Yu Chen, Yi-Jun Shen, Ming-Hui Ye in BMC Genomics (2023)

  3. Article

    Open Access

    Colonization with ubiquitous protist Blastocystis ST1 ameliorates DSS-induced colitis and promotes beneficial microbiota and immune outcomes

    Blastocystis is a species complex that exhibits extensive genetic diversity, evidenced by its classification into several genetically distinct subtypes (ST). Although several studies have shown the relationships ...

    Lei Deng, Lukasz Wojciech, Chin Wen Png in npj Biofilms and Microbiomes (2023)

  4. Article

    Open Access

    An intranasal influenza virus-vectored vaccine prevents SARS-CoV-2 replication in respiratory tissues of mice and hamsters

    Current available vaccines for COVID-19 are effective in reducing severe diseases and deaths caused by SARS-CoV-2 infection but less optimal in preventing infection. Next-generation vaccines which are able to ...

    Shaofeng Deng, Ying Liu, Rachel Chun-Yee Tam, Pin Chen in Nature Communications (2023)

  5. Article

    Open Access

    OTUB1 promotes osteoblastic bone formation through stabilizing FGFR2

    Bone homeostasis is maintained by the balance between osteoblastic bone formation and osteoclastic bone resorption. Dysregulation of this process leads to multiple diseases, including osteoporosis. However, th...

    Qiong Zhu, Yesheng Fu, Chun-** Cui, Yi Ding in Signal Transduction and Targeted Therapy (2023)

  6. Article

    Open Access

    Parental hesitancy against COVID-19 vaccination for children and associated factors in Taiwan

    Since July 2021, some countries and regions have initiated the vaccination of minors against coronavirus disease (COVID-19), and parental COVID-19 vaccine hesitancy will affect the vaccination of minors. We ai...

    **g-Shan Deng, Jau-Yuan Chen, **ao-Qing Lin, Chun-Lian Huang in BMC Public Health (2023)

  7. Article

    Open Access

    Comprehensive prognostic effects of systemic inflammation and Insulin resistance in women with breast cancer with different BMI: a prospective multicenter cohort

    To investigate the prognostic value of systemic inflammation and insulin resistance in women with breast cancer with different body mass index (BMI). This multicenter, prospective study included 514 women with...

    Guo-Tian Ruan, Hai-Lun **e, Chun-Lei Hu, Chen-An Liu, He-Yang Zhang in Scientific Reports (2023)

  8. Article

    Retraction Note: Cognitive learning performance assessment and analysis with CSCL applied on the NetGuru platform and CSPL applied on the TAoD platform for the network experiment class

    Yung-Hui Chen, Wei-Chun Lee, Chun-Hsiung Tseng in The Journal of Supercomputing (2023)

  9. Article

    Open Access

    The development of a cSMART-based integrated model for hepatocellular carcinoma diagnosis

    Hepatocellular carcinoma (HCC) generally arises from a background of liver cirrhosis (LC). Patients with cirrhosis and suspected HCC are recommended to undergo serum biomarker tests and imaging diagnostic eval...

    Tong Wu, Rong Fan, Jian Bai, Zhao Yang, Yun-Song Qian in Journal of Hematology & Oncology (2023)

  10. Article

    Open Access

    Long-term presence of autoantibodies in plasma of cured leprosy patients

    Autoantibodies have been detected in leprosy patients, indicating that infection with M. leprae may lead to autoimmune disorders. However, whether autoimmune response last until patients are cured is unknown. Kno...

    ** Yang, Hua Dong, Yi-Qun Kuang, **u-Feng Yu, Heng Long in Scientific Reports (2023)

  11. Article

    Open Access

    AGA induces sub-G1 cell cycle arrest and apoptosis in human colon cancer cells through p53-independent/p53-dependent pathway

    Despite the advancement in chemotherapeutic drugs for colon cancer treatment, it is still a life-threatening disease worldwide due to drug resistance. Therefore, an urgently needed to develop novel drugs for c...

    Bou-Yue Peng, Abhinay Kumar Singh, Chun-Hao Chan, Yue-Hua Deng, Pin-Ying Li in BMC Cancer (2023)

  12. Article

    Open Access

    Spectrum of the S-wave fully-heavy tetraquark states

    In present work, spectrum of the S-wave fully-heavy tetraquark states \(QQ\bar{Q}\bar{Q}\) ...

    Jie Zhang, **-Bao Wang, Gang Li, Chun-Sheng An in The European Physical Journal C (2022)

  13. Article

    Open Access

    Correction: CRISPR FISHer enables high-sensitivity imaging of nonrepetitive DNA in living cells through phase separation-mediated signal amplification

    **n-Yuan Lyu, Yuan Deng, **ao-Yan Huang, Zhen-Zhen Li, Guo-Qing Fang in Cell Research (2022)

  14. Article

    Open Access

    Differential transcriptomic landscapes of multiple organs from SARS-CoV-2 early infected rhesus macaques

    SARS-CoV-2 infection causes complicated clinical manifestations with variable multi-organ injuries, however, the underlying mechanism, in particular immune responses in different organs, remains elusive. In th...

    Chun-Chun Gao, Man Li, Wei Deng, Chun-Hui Ma, Yu-Sheng Chen in Protein & Cell (2022)

  15. Article

    Open Access

    Targeting UHRF1-SAP30-MXD4 axis for leukemia initiating cell eradication in myeloid leukemia

    Aberrant self-renewal of leukemia initiation cells (LICs) drives aggressive acute myeloid leukemia (AML). Here, we report that UHRF1, an epigenetic regulator that recruits DNMT1 to methylate DNA, is highly exp...

    Cheng-Long Hu, Bing-Yi Chen, Zijuan Li, Tianbiao Yang, Chun-Hui Xu in Cell Research (2022)

  16. Article

    Open Access

    Accuracy of calculating mechanical power of ventilation by one commonly used equation

    Gattinoni’s equation, $${\text{MP}}_{{{\text{rs}}}} \, = \,0.098\, \times \,{\text{RR}}\, \times \,\left[ {{\text{V}}_{T} ^{2} \left( {\frac{1...

    Shin-Hwar Wu, Chew-Teng Kor, I.-Chieh Mao in Journal of Clinical Monitoring and Computi… (2022)

  17. Article

    Fungal diversity notes 1512–1610: taxonomic and phylogenetic contributions on genera and species of fungal taxa

    This article is the 14th in the Fungal Diversity Notes series, wherein we report 98 taxa distributed in two phyla, seven classes, 26 orders and 50 families which are described and illustrated. Taxa in this stu...

    Ruvishika S. Jayawardena, Kevin D. Hyde, Song Wang, Ya-Ru Sun in Fungal Diversity (2022)

  18. Article

    Open Access

    CRISPR FISHer enables high-sensitivity imaging of nonrepetitive DNA in living cells through phase separation-mediated signal amplification

    The dynamic three-dimensional structures of chromatin and extrachromosomal DNA molecules regulate fundamental cellular processes and beyond. However, the visualization of specific DNA sequences in live cells, ...

    **n-Yuan Lyu, Yuan Deng, **ao-Yan Huang, Zhen-Zhen Li, Guo-Qing Fang in Cell Research (2022)

  19. Article

    Open Access

    The low-lying hidden- and double-charm tetraquark states in a constituent quark model with instanton-induced interaction

    Spectrum of the low-lying hidden- and double-charm tetraquark states are investigated in a nonrelativistic quark potential model, where the instanton-induced interaction is taken as the residual spin-dependent...

    **-Bao Wang, Gang Li, Chun-Sheng An, Cheng-Rong Deng in The European Physical Journal C (2022)

  20. Article

    Design and application of a multichannel “cross” hot tearing tendency device: A study on hot tearing tendency of Al alloys

    Hot tearing is one of the most serious defects during the casting solidification process. In this study, a new type of multichannel “cross” hot tearing device was designed. The hot cracks initiation and propag...

    Ming Su, Wen-tao Zheng, Deng-ke Fu, Hong-jun Huang, **ao-jiao Zuo in China Foundry (2022)

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