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Article
Open AccessProtein disorder in plants: a view from the chloroplast
The intrinsically unstructured state of some proteins, observed in all living organisms, is essential for basic cellular functions. In this field the available information from plants is limited but it has bee...
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Chapter and Conference Paper
Interface Similarity Improves Comparison of DNA-Binding Proteins: The Homeobox Example
The recently published 3D-footprint database contains an up-to-date repository of protein-DNA complexes of known structure that belong to different superfamilies and bind to DNA with distinct specificities. Th...
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Article
HvFT1 (VrnH3) drives latitudinal adaptation in Spanish barleys
In barley, three genes are responsible for the vernalization requirement: VrnH1, VrnH2 and VrnH3. The winter growth habit of barley requires the presence of a recessive VrnH1 allele, together with an active VrnH2
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Article
Open AccessEvolutionary divergence of chloroplast FAD synthetase proteins
Flavin adenine dinucleotide synthetases (FADSs) - a group of bifunctional enzymes that carry out the dual functions of riboflavin phosphorylation to produce flavin mononucleotide (FMN) and its subsequent adeny...
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Article
Open AccessPrediction of TF target sites based on atomistic models of protein-DNA complexes
The specific recognition of genomic cis-regulatory elements by transcription factors (TFs) plays an essential role in the regulation of coordinated gene expression. Studying the mechanisms determining binding spe...
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Article
OPCML at 11q25 is epigenetically inactivated and has tumor-suppressor function in epithelial ovarian cancer
Epithelial ovarian cancer (EOC), the leading cause of death from gynecological malignancy, is a poorly understood disease. The typically advanced presentation of EOC with loco-regional dissemination in the per...
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Article
Crystal: clear difference from glass