36 Result(s)

Article

Relative Response of Biological and Non-Biological Monitors in a Coastal Environment

A field study was carried out in the spring and summer of 2003 (2 months each), to assess the efficiency of alternative exposure modes of biological monitors – lichen biomass and tree-bark biomass – together w...

A. Machado, M. C. Freitas, A. M. G. Pacheco in Journal of Atmospheric Chemistry (2004)

Article

Ancestim (recombinant human stem cell factor, SCF) in association with filgrastim does not enhance chemotherapy and/or growth factor-induced peripheral blood progenitor cell (PBPC) mobilization in patients with a prior insufficient PBPC collection

Up to a third of autologous transplantation candidates fail to mobilize hematopoietic progenitors into the peripheral blood with chemotherapy and/or growth factor treatment, thus requiring innovative mobilizat...

M G da Silva, P Pimentel, A Carvalhais, I Barbosa, A Machado… in Bone Marrow Transplantation (2004)

Article

Defibrotide as salvage therapy for refractory veno-occlusive disease of the liver complicating allogeneic bone marrow transplantation

A 30-year-old woman developed veno-occlusive disease of the liver during an allogeneic BMT for acute leukemia. Treatment with recombinant human tissue plasminogen activator and heparin resulted in an incomplet...

MM Abecasis, JP Conceição Silva, I Ferreira, A Guimarães… in Bone Marrow Transplantation (1999)

Article

Relapsed chronic myeloid leukemia in accelerated phase 10 years after allogeneic bone marrow transplantation: full chimera reconversion with donor peripheral blood stem cells infusion

We report the case of a 44-year-old male who relapsed in accelerated phase chronic myeloid leukemia 10 years after a successful bone marrow transplantation from his HLA-identical brother, and 3 years after 12 ...

A Guimarães, A Machado, S Carvalho, H Alaiz, L Vieira… in Bone Marrow Transplantation (1998)

Article

PBPC as an alternative cell therapy for post-transplant relapse in CML

MM Abecasis, A Guimarães, A Machado, L Vieira, G Boavida… in Bone Marrow Transplantation (1998)

Chapter

The Iron Chelator Desferrioxamine Protects Against MPP⁺ Neurotoxicity

There is increasing evidence that degeneration of nigrostriatal dopaminergic neurons in Parkinson’s disease is associated with and may be even due to an active toxic process involving highly reactive oxygen sp...

E. R. Matarredona, M. Santiago, A. Machado, J. Cano in Neurochemistry (1997)

Article

Gastric duplication cyst: case report

We report a gastric duplication cyst in an undernourished 5-month-old child suffering from anorexia, vomiting, and melena. Clinical presentation was consistent with a Meckel's diverticulum, which, however, was...

L. Cruz, M. Gonçalo, J. Leão, J. Reis, I. Lourenço, A. Machado in European Radiology (1994)

Article

Effects of temperature on a moth auditory receptor

Measurements of the thoracic temperature and recordings of the spike activity of the most sensitive auditory receptor (A1 cell) were made in Empyreuma pugione (Arctiidae, Ctenuchinae). The temperature range teste...

F. Coro, M. Pérez, A. Machado in Journal of Comparative Physiology A (1994)

Article

Effects of neonatal bilateral eye enucleation on postnatal development of the monoamines in posterior thalamus of the rat

Levels of dopamine (DA), noradrenaline (NA) and 5-hydroxytryptamine (serotonin, 5-HT) and their metabolites, and the activities of tyrosine hydroxylase (TH), tryptophan hydroxylase (TPH) and monoamine oxidase ...

M. L. Vizuete, M. Santiago, A. J. Herrera… in Journal of Neural Transmission / General S… (1991)

Article

Hyperoxia and aging increase the guanylate cyclase activity of the rat lung

Age-associated changes on guanylate cyclase activity in the lung were investigated using male Wistar rats of ages ranging from 1 to 24 months. In 3 to 24 month old rats there is an increase about 3–4 fold in t...

C. Santa Maria, E. Revilla, I. Fabregat, A. Machado in AGE (1989)

Article

Ultrafiltration as concentration step in hyaluronate lyase production

Clarification with filter aid and subsequent concentration by ultrafiltration of hyaluronate lyase fermentation broth was studied. Activity recoveries for clarification and concentration were practically 100% ...

J. Bautista, E. Chico, A. Machado in Biotechnology Letters (1986)

Article

Cell removal from fermentation broth by flocculation + sedimentation

Cell separation by flocculation+sedimentation ofStreptoccocus equisimilis cultivation for hyaluronate lyase recovery, was investigated as a function of the pH of the fermentation broth, using three different cati...

J. Bautista, E. Chico, A. Machado in Biotechnology Letters (1986)

Article

Increase of hyaluronate lyase productivity by repeated batch fermentation

The production of hyaluronate lyase (E.C.4.2.2.1.), HL, byStreptococcus equisimilis strain SHL-03 has been studied under repeated batch culture conditions with fixed harvest volume (discharged fraction, α=0.875)....

J. Bautista, E. Chico, A. Machado in Biotechnology Letters (1985)

Article

Intramitochondrial inclusions in maturing and senescent muscle cells of rat myocardium

Intramitochondrial myelin-like structures were found in ventricular myocardial cells of the rat heart. These inclusions were found in both the first 2 postnatal weeks and in senescent stages. The origin of suc...

J. Cano, A. Machado in Experientia (1984)

Article

Age-related quantitative changes in enzyme activities of rat brain

The patterns of brain enzymes linked to energy metabolism have been determined in rats aged between 3 and 21 months and compared to those of the develo** brain as an estimate of the senescent energy capacity...

J. Vitorica, A. Andrés, J. Satrústegui, A. Machado in Neurochemical Research (1981)