28 Result(s)
within
**aosong Gu
Cell Biology
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Article
Open AccessRab8a/Rab11a regulate intercellular communications between neural cells via tunneling nanotubes
Tunneling nanotubes (TNTs) are F-actin-based membrane tubes, and can form between cultured cells and within vital tissues. TNTs mediate intercellular communications that range from electrical signaling to the ...
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Article
MiR-340 Regulates Fibrinolysis and Axon Regrowth Following Sciatic Nerve Injury
After peripheral nerve injury, the degenerative debris and inflammatory alterations at the injury site may block the elongation of regenerating axons to reach target organs. Tissue plasminogen activator (tPA),...
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Article
Open AccessmiR-129 controls axonal regeneration via regulating insulin-like growth factor-1 in peripheral nerve injury
The microenvironment of peripheral nerve regeneration consists of multiple neurotrophic factors, adhesion molecules, and extracellular matrix molecules, secreted by unique glial cells in the peripheral nerve s...
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Open AccessMolecular Regulatory Mechanism and Toxicology of Neurodegenerative Processes in MPTP/Probenecid-Induced Progressive Parkinson’s Disease Mice Model Revealed by Transcriptome
Parkinson’s disease (PD) is a neurodegenerative disease caused by a variety of unclear complex pathogenic factors. The 1-methyl-4-phenyl-1, 2, 3, 6-tetrahydropyridine/probenecid (MPTP/p)-induced progressive PD...
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Article
Open AccessBUB1B and circBUB1B_544aa aggravate multiple myeloma malignancy through evoking chromosomal instability
Multiple myeloma (MM) is an incurable plasma cell malignancy in the bone marrow characterized by chromosome instability (CIN), which contributes to the acquisition of heterogeneity, along with MM progression, ...
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Article
Chitosan Nerve Grafts Incorporated with SKP-SC-EVs Induce Peripheral Nerve Regeneration
Repair of long-distance peripheral nerve defects remains an important clinical problem. Nerve grafts incorporated with extracellular vesicles (EVs) from various cell types have been developed to bridge periphe...
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Article
Open AccessThe impact of the gut microbiome on tumor immunotherapy: from mechanism to application strategies
Immunotherapy is one of the fastest develo** areas in the field of oncology. Many immunological treatment strategies for refractory tumors have been approved and marketed. Nevertheless, much clinical and pre...
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Open AccessThe Transcription Factor Ets1 Influences Axonal Growth via Regulation of Lcn2
Transcription factors are essential for the development and regeneration of the nervous system. The current study investigated key regulatory transcription factors in rat spinal cord development via RNA sequen...
